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22 March 2023 | Story Mariette Joubert | Photo Unsplash
Social work

South Africa celebrated Human Rights Day and World Social Work Day on 21 March 2023. Social work is a profession that advocates for the human rights of people as well as focuses on the responsibility that comes with these rights. Just as the Bill of Rights is the cornerstone of democracy and protects our rights, the social work code of ethics is the cornerstone that ensures quality social work services. 

The University of the Free State (UFS) second-year social work students took an oath on 22 March which binds them to the social work code of ethics. Social workers have the Global Agenda for Social Work and Social Development which consists of four pillars. Focus is drawn to the last pillar, Strengthening Recognition of the Importance of Human Relationships. Human relationships are the core of social work and social development. These relationships take various forms, including social, personal, interpersonal, and therapeutic relationships, among various people and in various settings. In relationships where people flourish, trust is crucial. In contrast, mistrust skews relationships in a negative way. 

Respecting diversity through joint social action

The Ubuntu pan-African philosophical framework is the greatest place to understand the significance of human relationships. To promote and strive for the strengthening of relationships, this year’s theme for Social Work Day is “Respecting Diversity Through Joint Social Action”. If we can stop criticising people that do not live, believe, or think according to our constructed standards of being, we will be able to do so much more as humanity. If we start embracing peoples’ diversities and take time to start building relationships with various people and bridge any existing gaps, we will realise that diversity is an integral aspect of changing the world in a positive manner. Corresponding to human rights and the theme of World Social Work Day, is the theme “Destigmatising intellectual disability through shifting attitudes” for Intellectual Disability Awareness Month [IDAM] which also takes place later in March. Another way through which we can start building relationships and embrace diversity is by participating in this year’s South African Federation for Mental Health challenge where CEOs of different institutions are challenged to spend one day in a wheelchair as part of an awareness-raising campaign to destigmatise intellectual disabilities.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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