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23 March 2023 | Story Rulanzen Martin | Photo Stephen Collett
From left: Hanlie Grobler, Senior Officer at the CFM; Prof Koos Terblans, Head of the Physics Department; Nonkululeko Phili, Assistant Officer at the CFM; and Edward Lee, Junior Lecturer and Researcher at the CFM. Photo: Stephen Collett

The Centre for Microscopy (CFM) in the Faculty of Natural and Agricultural Sciences at the University of the Free State (UFS) unveiled a sophisticated JEOL High Resolution Transmission Electron Microscope (HRTEM) during a two-day microscopy conference on 14 and 15 March 2023. The microscope is part of a larger investment into research equipment worth R65 million. 

Speaking at the opening of the conference, Prof Corli Witthuhn, out-going Vice-Rector: Research and Internationalisation, said the microscope purchase “is a significant milestone in the university’s bid for cutting-edge research”. The HRTEM is part of a larger consignment of JEOL equipment at the UFS and, according to Dr Sarah Harper from JEOL UK, it places the UFS in a unique position.  

UFS at the forefront in using electron microscopes  

The HRTEM microscope can be utilised across disciplines and will give the UFS an advantage in uncovering new solutions and creating national and international interdisciplinary research collaborations. “The UFS is at the forefront in this field in SA and continues to push the boundaries,” Prof Witthuhn said. This move will also positively impact the training of honours, master’s, and doctoral students. 

Prof Danie Vermeulen, Dean of the Faculty of Natural and Agricultural Sciences, reiterated Prof Witthuhn’s sentiments by saying that this equipment will set the faculty apart from its competitors. “The faculty already reached the goals of Vision 130 by being proactive,” he said. In the past seven years more than R300 million worth of equipment was acquired by the faculty, but he added that to be the best is not just about the best equipment – “the data coming from using this equipment is what will make the real difference”.

Prof Koos Terblans
Prof Koos Terblans opens the conference on 14 March 2023. Photo: Stephen Collett .

Road to the JEOL HRTEM started in 2018

The process of acquiring a HRTEM microscope started in 2018 and was concluded with the purchasing of the JOEL microscopes in March 2020, a few weeks before the first COVID-19 lockdown. The purchase was made possible through the collaboration between the faculties of Natural and Agricultural Sciences and Health Sciences. Thanks to the dedication of staff members in the Centre for Microscopy and Physics, it was possible to accept delivery of the new HRTEM in June 2021. Prof Koos Terblans, Head of the Physics Department and the Centre for Microscopy, who led the entire project, said this was one of the “proudest moments in my career”.  

Installing the equipment involved various university resources, including the University Estates Department, which had to make additional structural changes to the room where the equipment is housed. This included digging two metres into the existing floor and placing the HRTEM on a 70-tonne solid concrete block, to ensure that the equipment was secure and vibration free.

Prof Terblans said now that the HRTEM from JEOL and its supporting equipment – the final piece of the R65 million research investment puzzle – is part of the faculty’s resources, it is up to the scientists and academics to utilise it for innovative research, enhance research productivity, and foster new collaborations. 

Edward Lee
Edward Lee shows the new HRTEM electron microscope to colleagues and conference attendees.Photo: Stephen Collett 

News Archive

UFS scientists involved in groundbreaking research to protect rhino horns
2010-07-27

Pictured from the left are: Prof. Paul Grobler (UFS), Prof. Antoinette Kotze (NZG) and Ms. Karen Ehlers (UFS).
Photo: Supplied

Scientists at the University of the Free State (UFS) are involved in a research study that will help to trace the source of any southern white rhino product to a specific geographic location.

This is an initiative of the National Zoological Gardens of South Africa (NZG).

Prof. Paul Grobler, who is heading the project in the Department of Genetics at the UFS, said that the research might even allow the identification of the individual animal from which a product was derived. This would allow law enforcement agencies not only to determine with certainty whether rhino horn, traded illegally on the international black market, had its origin in South Africa, but also from which region of South Africa the product came.

This additional knowledge is expected to have a major impact on the illicit trade in rhino horn and provide a potent legal club to get at rhino horn smugglers and traders.

The full research team consists of Prof. Grobler; Christiaan Labuschagne, a Ph.D. student at the UFS; Prof. Antoinette Kotze from the NZG, who is also an affiliated professor at the UFS; and Dr Desire Dalton, also from the NZG.

The team’s research involves the identification of small differences in the genetic code among white rhino populations in different regions of South Africa. The genetic code of every species is unique, and is composed of a sequence of the four nucleotide bases G, A, T and C that are inherited from one generation to the next. When one nucleotide base is changed or mutated in an individual, this mutated base is also inherited by the individual's progeny.

If, after many generations, this changed base is present in at least 1% of the individuals of a group, it is described as a single nucleotide polymorphism (SNP), pronounced "snip". Breeding populations that are geographically and reproductively isolated often contain different patterns of such SNPs, which act as a unique genetic signature for each population.

The team is assembling a detailed list of all SNPs found in white rhinos from different regions in South Africa. The work is done in collaboration with the Pretoria-based company, Inqaba Biotech, who is performing the nucleotide sequencing that is required for the identification of the SNPs.

Financial support for the project is provided by the Advanced Biomolecular Research cluster at the UFS.

The southern white rhino was once thought to be extinct, but in a conservation success story the species was boosted from an initial population of about 100 individuals located in KwaZulu-Natal at the end of the 19th century, to the present population of about 15 000 individuals. The southern white rhino is still, however, listed as “near threatened” by the World Wildlife Fund (WWF).

Media Release:
Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za 
27 July 2010



 

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