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23 March 2023 | Story Rulanzen Martin | Photo Stephen Collett
From left: Hanlie Grobler, Senior Officer at the CFM; Prof Koos Terblans, Head of the Physics Department; Nonkululeko Phili, Assistant Officer at the CFM; and Edward Lee, Junior Lecturer and Researcher at the CFM. Photo: Stephen Collett

The Centre for Microscopy (CFM) in the Faculty of Natural and Agricultural Sciences at the University of the Free State (UFS) unveiled a sophisticated JEOL High Resolution Transmission Electron Microscope (HRTEM) during a two-day microscopy conference on 14 and 15 March 2023. The microscope is part of a larger investment into research equipment worth R65 million. 

Speaking at the opening of the conference, Prof Corli Witthuhn, out-going Vice-Rector: Research and Internationalisation, said the microscope purchase “is a significant milestone in the university’s bid for cutting-edge research”. The HRTEM is part of a larger consignment of JEOL equipment at the UFS and, according to Dr Sarah Harper from JEOL UK, it places the UFS in a unique position.  

UFS at the forefront in using electron microscopes  

The HRTEM microscope can be utilised across disciplines and will give the UFS an advantage in uncovering new solutions and creating national and international interdisciplinary research collaborations. “The UFS is at the forefront in this field in SA and continues to push the boundaries,” Prof Witthuhn said. This move will also positively impact the training of honours, master’s, and doctoral students. 

Prof Danie Vermeulen, Dean of the Faculty of Natural and Agricultural Sciences, reiterated Prof Witthuhn’s sentiments by saying that this equipment will set the faculty apart from its competitors. “The faculty already reached the goals of Vision 130 by being proactive,” he said. In the past seven years more than R300 million worth of equipment was acquired by the faculty, but he added that to be the best is not just about the best equipment – “the data coming from using this equipment is what will make the real difference”.

Prof Koos Terblans
Prof Koos Terblans opens the conference on 14 March 2023. Photo: Stephen Collett .

Road to the JEOL HRTEM started in 2018

The process of acquiring a HRTEM microscope started in 2018 and was concluded with the purchasing of the JOEL microscopes in March 2020, a few weeks before the first COVID-19 lockdown. The purchase was made possible through the collaboration between the faculties of Natural and Agricultural Sciences and Health Sciences. Thanks to the dedication of staff members in the Centre for Microscopy and Physics, it was possible to accept delivery of the new HRTEM in June 2021. Prof Koos Terblans, Head of the Physics Department and the Centre for Microscopy, who led the entire project, said this was one of the “proudest moments in my career”.  

Installing the equipment involved various university resources, including the University Estates Department, which had to make additional structural changes to the room where the equipment is housed. This included digging two metres into the existing floor and placing the HRTEM on a 70-tonne solid concrete block, to ensure that the equipment was secure and vibration free.

Prof Terblans said now that the HRTEM from JEOL and its supporting equipment – the final piece of the R65 million research investment puzzle – is part of the faculty’s resources, it is up to the scientists and academics to utilise it for innovative research, enhance research productivity, and foster new collaborations. 

Edward Lee
Edward Lee shows the new HRTEM electron microscope to colleagues and conference attendees.Photo: Stephen Collett 

News Archive

UFS doctors fight childhood cancer
2016-09-02

Description: Childhood cancer  Tags: Childhood cancer

Prof David Stones and Dr Jan du Plessis of the
University of Free State’s paediatric oncology ward
are helping little lives, one patient at a time.
Photo: Nonsindiso Qwabe

Of 23 paediatric oncology specialists nationally, Prof David Stones and Dr Jan du Plessis of the University of Free State are the only ones in the province.

Committed to giving holistic care to their patients, the two doctors specialise in all types of childhood cancers, the most common being leukaemia, brain tumour, and nephroblastoma.

They describe the childhood malignancy as a lethal disease, unpredictability being its harshest trait. “With cancer, you can just never know. It precipitates and multiplies, and leads to the failure of other organs. You can just always hope, and keep trying,” said Du Plessis.

The paediatric oncology unit of the Universitas Academic Hospital, their unit, is the liveliest floor in the entire building. It is also the third busiest in South Africa, serving a demographic that spans the Free State and Northern Cape, as well as parts of North West, Eastern Cape and Lesotho.

Each year, the unit receives more than 100 new childhood cancer patients. In 2015, the unit had 113 newly diagnosed patients, an increase from 93 in 2014.

Lack of knowledge poses a serious challenge
According to the two experts, the lack of insight and awareness of the disease remain a big challenge to fighting it. “It is frustrating. Parents and family members don’t know anything about it. Nurses and doctors aren’t always clinically trained to pick up the early warning signs. By the time a diagnosis is made, life and death is on a 50% margin,” Stones said.

Poverty, a lack of resources, overcrowding and a range of health issues are other factors that have a profound effect on the diagnosis and treatment of the disease.

Making a contribution that will last
With a desire to see an improvement on life outcomes in the health sector, the team is focusing on educating the country’s doctors of tomorrow. Their unit is the only one in the country that actively involves medical students in an oncology unit, giving them practical experience and exposure to the individual cases each patient presents. They have also produced a substantial amount of research literature on childhood malignancies in South Africa as a developing country.

Driven by passion to see a better South Africa
The doctors are passionate about the work they do, and remain hopeful there will be a change in the incidence of childhood cancer   not just in decreased levels of the disease, but also in the overall state of well-being of young South Africans.

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