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23 March 2023 | Story Rulanzen Martin | Photo Stephen Collett
From left: Hanlie Grobler, Senior Officer at the CFM; Prof Koos Terblans, Head of the Physics Department; Nonkululeko Phili, Assistant Officer at the CFM; and Edward Lee, Junior Lecturer and Researcher at the CFM. Photo: Stephen Collett

The Centre for Microscopy (CFM) in the Faculty of Natural and Agricultural Sciences at the University of the Free State (UFS) unveiled a sophisticated JEOL High Resolution Transmission Electron Microscope (HRTEM) during a two-day microscopy conference on 14 and 15 March 2023. The microscope is part of a larger investment into research equipment worth R65 million. 

Speaking at the opening of the conference, Prof Corli Witthuhn, out-going Vice-Rector: Research and Internationalisation, said the microscope purchase “is a significant milestone in the university’s bid for cutting-edge research”. The HRTEM is part of a larger consignment of JEOL equipment at the UFS and, according to Dr Sarah Harper from JEOL UK, it places the UFS in a unique position.  

UFS at the forefront in using electron microscopes  

The HRTEM microscope can be utilised across disciplines and will give the UFS an advantage in uncovering new solutions and creating national and international interdisciplinary research collaborations. “The UFS is at the forefront in this field in SA and continues to push the boundaries,” Prof Witthuhn said. This move will also positively impact the training of honours, master’s, and doctoral students. 

Prof Danie Vermeulen, Dean of the Faculty of Natural and Agricultural Sciences, reiterated Prof Witthuhn’s sentiments by saying that this equipment will set the faculty apart from its competitors. “The faculty already reached the goals of Vision 130 by being proactive,” he said. In the past seven years more than R300 million worth of equipment was acquired by the faculty, but he added that to be the best is not just about the best equipment – “the data coming from using this equipment is what will make the real difference”.

Prof Koos Terblans
Prof Koos Terblans opens the conference on 14 March 2023. Photo: Stephen Collett .

Road to the JEOL HRTEM started in 2018

The process of acquiring a HRTEM microscope started in 2018 and was concluded with the purchasing of the JOEL microscopes in March 2020, a few weeks before the first COVID-19 lockdown. The purchase was made possible through the collaboration between the faculties of Natural and Agricultural Sciences and Health Sciences. Thanks to the dedication of staff members in the Centre for Microscopy and Physics, it was possible to accept delivery of the new HRTEM in June 2021. Prof Koos Terblans, Head of the Physics Department and the Centre for Microscopy, who led the entire project, said this was one of the “proudest moments in my career”.  

Installing the equipment involved various university resources, including the University Estates Department, which had to make additional structural changes to the room where the equipment is housed. This included digging two metres into the existing floor and placing the HRTEM on a 70-tonne solid concrete block, to ensure that the equipment was secure and vibration free.

Prof Terblans said now that the HRTEM from JEOL and its supporting equipment – the final piece of the R65 million research investment puzzle – is part of the faculty’s resources, it is up to the scientists and academics to utilise it for innovative research, enhance research productivity, and foster new collaborations. 

Edward Lee
Edward Lee shows the new HRTEM electron microscope to colleagues and conference attendees.Photo: Stephen Collett 

News Archive

Small things matter
2017-01-17

 Description: Prof Felicity Burt  Tags: Prof Felicity Burt

Prof Felicity Burt (right) and Dr Dominique Goedhals
from the Department of Medical Microbiology and
Virology at the University of the Free State.
Photo: Anja Aucamp



The newly established virology section at the University of the Free State (UFS) boasts world class expertise. Not only are they one of just five laboratories in the country tasked with specialised HIV testing, but current research generates publications and subsidised funding.

The driving force behind this initiative is passionate and dedicated people who invest long hours into vital research. One such person is Prof Felicity Burt, who eloquently guides her students while making impressive progress within her own field of interest: vector-borne and zoonotic diseases. Prof Burt was recently awarded a research chair (2016-2020) to, among other areas, investigate medically significant vector-borne and zoonotic viruses currently circulating.

That means that her research focus is mainly on viruses transmitted by mosquitoes and ticks, and viruses transmitted from animals to humans. “Yes,” she laughs, “I catch mosquitoes and check them for viruses.”

Becoming familiar with different viruses
As if big screen moments like Outbreak and Contagion did not create enough virus paranoia, the world was recently bombarded by real world Ebola and Zika outbreaks. But awareness, Prof Burt says, is not a bad thing. “Years ago, when people heard that I did Ebola research, they got that distant look in their eyes, and changed the subject. One outbreak later, backed by many media reports, and Ebola is almost a household name. The same goes for the recent Zika virus outbreak in South America.”

The more familiar people become with these types of viruses, the better, Prof Burt feels. However, getting the right message across is not always that easy. The Zika virus outbreak, for example, was a very large outbreak and therefore presented large numbers of affected people. Generally, not everyone infected with an arbovirus will necessarily present with symptoms. But because vector-borne viruses can spread to new areas, surveillance and awareness is important. Here in Bloemfontein, Prof Burt and her team are establishing surveillance programmes.

Gaining knowledge and preventative measures
So, next time you get all wound up about a “biological disaster”, rest assured that competent people like Prof Burt and her colleagues continuously scan the environment to gain knowledge and develop preventive measures should any risks be looming. For example, developing next-generation vaccines that are very effective, but without risk – since they are not built on the virus itself, but only on the part of the virus that will induce an immune response.

Currently, Prof Burt is also looking into the relationship between the Sindbis virus and arthritis. It is clear that we can expect many exciting findings from the UFS’s new virology unit.

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