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29 March 2023
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Story Samkelo Fetile
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Photo Simba Matema
From left to right: Prof Jean Bernard Lekana-Douki, Director General at the CIRMF; Prof Francis Petersen, Rector and Vice-Chancellor of the UFS; and Prof Jean-Fabrice Yala, Scientific and Technical Director at the CIRMF.
The University of the Free State (UFS) recently welcomed senior members from the International Centre for Medical Research in Franceville (CIRMF), Gabon to sign a Memorandum of Understanding (MoU) between the two entities.
CIRMF is a non-profit medical research centre that was established in 1974. Its primary focus is on diagnosing infectious diseases that pose immediate problems in Gabon and the Central African sub-region. The centre is dedicated to improving public health through various initiatives, including the training of Gabonese health executives in doctoral and post-doctoral education.
“The signing of the MoU with CIRMF is a step in the right direction as the UFS continues to strengthen its footprint on the African Continent. This is seminal in driving the university’s internationalisation processes and opening an avenue to expanding research networks, especially in the African continent,” said Bonolo Makhalemele, Coordinator of strategic projects at the Office for International Affairs, UFS.
In the interest of developing broader research collaborations, the CIRMF delegation met with some UFS academics in a series of engagements, particularly in the Health Sciences Faculty and the Natural and Agricultural Sciences Faculty. “The integration of knowledge and practices that emanate from the continent provides opportunities for the co-creation of knowledge that can be shared with the rest of the world,” said Kagiso Ngake, Coordinator for Partnerships, Collaborative Degrees, and Outgoing Mobility at the Office for International Affairs, UFS.
A concrete roadmap was established to formalise the collaborations that resulted from these engagements and will commence as soon as April 2023. “We have laid a solid foundation and are on the way to a strong and rich partnership!” exclaimed Prof Jean Bernard Lekana-Douki, Director General at the CIRMF.
Prof Francis Petersen, Rector, and Vice-Chancellor of the UFS, further highlighted how the newly established partnership with the CIRMF aligns with the mandate of the UFS Vision 130 of expanding the UFS Africa research network.
New research informs improved treatment of brain inflammation
2017-10-13
Dr Adepemi Ogundeji, researcher in the Department of Microbial,
Biochemical and Food Biotechnology at the
University of the Free State,and Dr Olihile Sebolai,
her study leader from the same department.
Photo: Charl Devenish
Microbiologist Dr Adepemi Ogundeji has uncovered a new use for an old medicine that can potentially save lives and money. Under the guidance of her study leader, Dr Olihile Sebolai, Dr Ogundeji set out to fight a fungal disease caused by Cryptococcus neoformans. Drs Ogundeji and Sebolai are from the University of the Free State Department of Microbial, Biochemical and Food Biotechnology.
Dr Ogundeji is passionate about education. “My aim will always be to transfer knowledge and skills in the microbiology field,” she said. “Dr Ogundeji’s study is celebrated in that it found a new purpose for existing medicines. An advantage of repositioning old medicines is by-passing clinical trials, which sometimes take 20 years, and the safety of such medicines is already known,” Dr Sebolai, explained.
Cryptococcus infections are difficult to control and often lead to brain inflammation. In layman’s terms: “Your brain is on fire”. People with HIV/Aids are especially vulnerable, surviving only about three months without treatment. Such patients may present with a Cryptococcus-emergent psychosis, and some with an out-of-control inflammatory condition when initiated on ARVs.
Dr Ogundeji found that the clinically recommended dosage of aspirin (anti-inflammatory medicine), and quetiapine (anti-psychotic medicine) is sufficient to control the infection. Her exceptional work was readily published in some of the foremost journals in her field, namely, Antimicrobial Agents and Chemotherapy and Frontiers in Microbiology