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17 May 2023 | Story NONSINDISO QWABE | Photo SUPPLIED
Matsimela Setenane
Matsimela Setenane speaking about his book Haeso ke Naheng at the launch event on the Qwaqwa Campus.

In celebration of African linguistic diversity and the power of indigenous creative expression, the UFS African Languages Press, in collaboration with the Academy for Multilingualism on the Qwaqwa Campus, kick-started Africa Month with the launch of the African Languages Press on the campus, as well as the Multilingual Hub, and finally, its first product, a book titled Haeso ke Naheng by former UFS Qwaqwa Campus student Matsimela Setenane.

The African Languages Press was launched on the Bloemfontein Campus in May 2022.

In her opening remarks, Dr Tholani Hlongwa, Deputy Director of the Academy of Multilingualism, said the Languages Press and Multilingual Hub would work together to publish high-quality original content in African languages. “We will promote writing in African languages and position the UFS as a hub, promoter, and preserver of African languages in South Africa. We want to support upcoming authors by providing high-quality editorial services and bridge the gap left by the mainstream publishing industry by increasing the publication of African languages, among other things.” 

A creative expression of the Sesotho language

Haeso ke Naheng, a fictional Sesotho novel, looks at the life of Thabo, an orphan who witnessed the takeover of his place of birth. He grows up to be a revolutionary Sesotho warrior who fights to reclaim his birthplace. His story resonates with his life; the author told the audience during the book launch. “Through writing this book, I discovered a lot about my origins as a Mosotho man. It is our responsibility as young people to continue digging to discover who we are so that we, too, will have knowledge to pass on to our children”, he said.

Setenane was born and bred in Qwaqwa and obtained his BSc degree majoring in Physics and Chemistry qualification from the Bloemfontein Campus in 2019. His love for Sesotho literature has grown over the years, and he hopes to produce more literature that celebrates the creative expression of his culture. He is currently busy with his first poetry anthology, which is also in Sesotho.

A platform to reignite free expression in indigenous languages

The guest speaker for the launch was Dr Edwin Mohatlane, who praised the UFS for the strides it's taking towards preserving and promoting African indigenous languages. “This is a milestone in the development of our languages. Our languages are doomed to extinction because of our attitudes towards them. I hope that the African Languages Press and the Multilingual Hub will be used to promote the literary and aesthetic talents in our languages”, he said.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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