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18 May 2023 | Story André Damons | Photo Supplied
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South Africa is facing increasing water stress due to a variety of factors.

South Africa, like the rest of Africa, is facing increasing water stress due to a variety of factors, including inadequate maintenance and investment in water and sanitation infrastructure, unequal access to water, poor water quality, and increasingly unsustainable water demand. Flooding and drought disasters and disruptions in water and sanitation services have become more frequent in recent years amidst a growing population in a semi-arid country.

In addition to the ongoing load shedding crisis we are facing, South Africa is rapidly approaching a situation where “water shedding” is becoming a tangible issue. Although it hasn’t reached a nationwide scale yet, the occurrence of disruptions in water supply systems due to shortages and a combination of other factors is growing significantly.

This situation is detrimental, not only to South Africa’s developmental goals but also to its socio-economic position within the Southern African development community region and the continent as a whole.

This is according to academics from the University of the Free State (UFS) and the University of Pretoria (UP) who were part of a group of academics and industry experts who did an independent assessment of Operation Vulindlela’s impact on South Africa. Pres Cyril Ramaphosa unveiled Operation Vulindlela – a joint initiative of the Presidency and National Treasury that aims to modernise and transform network industries – in 2020 as the vehicle to “fast-track the delivery of economic reforms”.

Prof Paul Oberholster, Director of the UFS Centre for Environmental Management and an expert in wastewater treatment, and Dr Yolandi Schoeman, his Postdoctoral Fellow, together with Prof Emma Archer, Professor in Geography and Environmental Studies at the University of Pretoria were asked by Rand Merchant Bank (RMB) to focus on water.

Bring about the structural change

RMB states in the report that it commissioned a body of work by academics and industry experts to independently evaluate whether the execution of policy initiatives set out by Operation Vulindlela, would bring about the structural change that is necessary to accelerate SA’s growth and employment. The subsequent parts of this report focus on three of the five network industries identified by Operation Vulindlela – electricity, water and transport (ports and rail).

“It was an honour to have been part of this project with RMB and to unpack and strategically assess the water sector in South Africa. We know that there are plenty of challenges, but there are also remarkable opportunities where we can implement solutions and demonstrate impact, bring about change and work hard in turning the situation around as a joint constructive collaborative approach.

“They are very keen on working with leaders in the water space with qualities of strategic thinking, innovation, collaboration, inclusivity, and a strong commitment to sustainable development. It is an impactful contribution indeed,” says Prof Oberholster.

In their sections of the report, under heading South Africa's Blue Revolution: Investing in a thriving water future South Africa, Prof Oberholster, Dr Schoeman and Prof Archer, focused on five themes, namely Water for planetary health, Water for development, Water for climate, resilience and the environment, Water for cooperation and The Water Decade of Action.

“We were asked to evaluate the viability of what is still left to be done in the water sector in South Africa. We were asked to contribute our thinking to the RMB handbook for the purpose of distribution to corporate and institutional clients. As part of our outcome we provided clear and unbiased direction to RMB’s clients on the joint initiative the likely impact of Operation Vulindlela on economic growth and what still needs to be done to turn the water sector around,” according to Prof Oberholster.

Guidelines to improve the country’s water situation

He says their aim was to give guidelines on how to improve the country’s water situation. He believes the work they have done with this assessment and on other occasions, will help the UFS in its goal to be a university that impactfully supports societal development as set out in Vision 130, which states: Our knowledge will continue to contribute to the development of the Free State, South Africa, and the African continent and to advance global knowledge and understanding.

As clean water and sanitation is Goal 6 of the 17 Sustainable Development Goals (SDGs), it is a further indication of the importance of this research and work.

According to Dr Schoeman, reports like these are important because they help raise awareness of the challenges and opportunities for achieving water security and sustainable development. They identify problems and bottlenecks within the industry, helping to target areas that require immediate attention and action. They provide potential solutions and enable dialogue to the problems identified, giving stakeholders a roadmap for action and providing essential background that can enable investment and further inform investment priorities.

“Such reports help to inform planning and decision-making processes by providing data, evidence, and recommendations based on research and analysis.  They encourage collaboration and coordination among stakeholders by providing a common understanding of the issues and potential solutions.

“They also provide guidance and recommendations for decision-makers to improve water resources management and governance. Water is a vital resource for human health, food security, energy production, environmental protection and more, so it is essential to recognise its worth and incorporate it into planning and policies,” says Dr Schoeman.

Blue Revolution

The academics also talks about the Blue Revolution – essential blue solutions – in supporting Operation Vulindlela which can enable a sustainable future for South Africa's water management system. The Blue Revolution in South Africa, write the academics, refers to a comprehensive strategy and functional implementation for modernising and transforming the country’s water sector. It aims to improve water management practices and enhance the water sector’s overall efficiency, effectiveness, and sustainability in enabling planetary health.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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