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09 November 2023 | Story André Damons | Photo SUPPLIED
Prof Atangana
Prof Abdon Atangana, a professor of Applied Mathematics at the University of the Free State (UFS), is the highest-ranked UFS scientist included in Stanford University’s World’s Top 2% Scientists list.

A professor of Applied Mathematics at the University of the Free State (UFS) is again the highest-ranked scientist from the institution included in Stanford University’s annual ranking of the top 2% of scientists in the world. 

Prof Abdon Atangana from the UFS’s Institute for Groundwater is ranked number one in applied mathematics, mathematical physics, mathematics, and statistics in the world, and number 260 in all of science, technology, and engineering in the Stanford University World’s Top 2% Scientists list. He is also ranked highest (5 620) of all the UFS scientists included in the career-long data set. 

‘Africans in Africa can impact the world’

“The ranking provides us with the impact of our outputs, and it shows that Africans can contribute to the development of science, technology, engineering, and mathematics while still in Africa,” Prof Atangana said. “This also shows that Africans in Africa can have impact on the world. My motivation is to tell the next generation that Africans do not always need to graduate from the top universities of the global North to make a global impact.  

“We must work hard to make our African universities reach the same level of those from the global North, such that a student from the global North will wish to enroll in our universities. The development of our continent does not rest on sport, music, and so forth alone, but on science, technology, engineering, and mathematics. Having the best scientists, mathematicians, and engineers in the world in Africa should be the strive of all Africans.” 

Three of the UFS’s SARChI Research Chairs have also been included in this list: Prof Hendrik Swart, Chair: Solid-state Luminescent and Advanced Materials (Applied Physics, ranked 40 269 in the single-year dataset); Prof Melanie Walker, Chair: Higher Education and Human Development (ranked 68 337); and Prof Maryke Labuschagne, Chair: Disease Resistance and Quality in Field Crops (Plant Sciences, 165 780).  

Other UFS scientists included in the single-year data set are: Prof John M. Carranza (Geology, 4 837); Prof Muhammad Altaf Khan ( Applied Mathematics, 6 366); Prof Maxim Finkelstein (Statistics/ Mathematical Statistics, 63 394); Prof Marianne Reid (School of Nursing, 72 861); Prof John Owen (Centre for Development Support, 103 368); Prof Brownhilder Neneh (Department of Business Management, 73 635); Prof Jorma Hölsä (Research Fellow: Department of Physics, 88 833); Prof Johann Beukes (Philosophy & Classics, 6 547 764); Rian Venter, (829 709); Dr Yuri Marusik (Zoology and Entomology, 553 619); Prof Robert Schall (Department of Mathematical Statistics and Actuarial Science, 276 681); Prof Deborah Posel (Department of Sociology, 275 535); Dr Vijay Kumar (Physics, 274 541); Dr Abhay Prakash Mishra (Pharmacology, 229 625); Prof RE Kroon (Physics, 226 554); Dr Krishnan Anand (Chemical Pathology, 235 300); Prof Andrew Marston (Chemistry, 147 147); Dr Seda Igret Araz (Applied Mathematics,125 824); Prof Jeanet Conradie (Chemistry, 106 521); Prof Louis Scott (Plant Sciences, 73 874); Prof Johan Grobbelaar (Plant Sciences, 97 722); Prof David Motaung (Physics, 53 553); Dr Samuel Nambile Cumber (Health Systems Research and Development, 555 563). 

Career-long data set 

The Stanford University rankings also include a list of the top 2% of world-class researchers based on citations over their full careers. Scientists are classified into 22 scientific fields and 174 sub-fields. Field- and subfield-specific percentiles are also provided for all scientists with at least five published papers. Career-long data is updated to the end of 2021, and single recent-year data pertain to citations received during calendar year 2021. The selection is based on the top 100 000 scientists by C-score (with and without self-citations) or a percentile rank of 2% or above in the sub-field.

The career-long data set includes the names of:

Prof Carranza (17 466); Prof Scott (55 882); Prof Reid (57 173); Prof Hölsä (64 402); Prof Grobbelaar (71 094); Prof Walker (78 239); Prof Andrew Marston (Chemistry, 84 484); Prof Schall (90 268); HA Snyman (Animal, Wildlife and Grassland Sciences, 96 374); Prof Swart (103 895); Robert WM Frater Cardiovascular Research Centre (111 896); Prof Frederick Kruger (Centre for Environmental Management,117 971); Prof Finkelstein (124 118); Prof Johan Visser (Geology, 125 331); Prof James C du Preez (Biotechnology, 168 841); Prof Posel (172 295); Prof Conradie (178 157); Prof Michael D MacNeil (Dairy and Animal Science, 184 193); Prof Khan (201 101); Prof Owen (262 897). 

“The representation of our researchers from a variety of disciplinary domains in this prestigious ranking, is confirmation of their excellence, impact, and the global esteem they hold. UFS is proud to be a home to scholars in our midst who take us incrementally forward as an institution because of their cutting-edge research,” said Prof Vasu Reddy, UFS Deputy Vice-Chancellor: Research and Internationalisation. 

  • Prof Atangana has also been shortlisted as one of the finalists for the prestigious Alkebulan Immigrants Impact Awards (AIIA) 2023, in the South African Flag Carrier category. Voting started on 1 November, and the award ceremony is set to take place on 23 November in Johannesburg. 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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