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Prof Frans Prinsloo takes on new leadership role in the Faculty of Economic and Management Sciences

14 November 2023 | Story Anthony Mthembu | Photo SUPPLIED

The Faculty of Economic and Management Sciences (EMS) at the University of the Free State (UFS) has appointed Prof Frans Prinsloo as the Vice-Dean: Learning, Teaching, Innovation, and Digitalisation. Prof Prinsloo officially started his new role on 1 November 2023. “I am excited at the prospect of being able to support the academics in the faculty, enabling them to develop successful graduates who will not only sustain themselves and their families, but who can also function in and contribute positively to a dynamic world being transformed by technology,” Prof Prinsloo indicated.

What the new role entails

According to Prof Prinsloo, the role includes overseeing and providing strategic leadership regarding the teaching and learning portfolio within the faculty. The portfolio he is responsible for looks at teaching and learning policies as well as the development of new curricula in the faculty, among others. In addition, as part of his work, he indicated that, “I will also have to ensure that the faculty’s teaching approaches remain relevant and responsive to our diverse body of students’ learning needs to ensure their academic success, but also to develop essential graduate attributes. A further focus will be that the curricula of our academic programmes position our graduates to be in demand by employers and enable them to contribute meaningfully to the economy and society.”

Furthermore, Prof Prinsloo is responsible for ensuring that the academic programmes within the faculty are of high quality and accredited by all relevant top industry bodies.

The future of the faculty

As an Auditing academic for more than 25 years and Director of the UFS School of Accountancy for the past five years, Prof Prinsloo plans to use the experience he has acquired, as well as the leadership positions he has held throughout his career, to lead the faculty to new heights. “I look forward to positioning the UFS Faculty of Economic and Management Sciences as a faculty with effective and cutting-edge teaching approaches to ensure our students’ academic success, and to have quality and unique academic programmes that draw top students from across South Africa, Africa, and beyond – in line with the UFS Vision 130,” he said.

In addition, part of what he aims to accomplish in his term as Vice-Dean is working to establish the faculty and its academics as recognised thought leaders and innovators as far as teaching and learning is concerned. Prof Prinsloo also highlighted that, “We also need to ensure that the successes attained by the faculty and its staff are shared within and outside of the UFS, and as such, I will also be responsible for strategically leading the marketing efforts of the faculty.”

However, his efforts to advance the faculty are not only focused on the progress of the staff and their offerings, but also on that of the students. In fact, he indicated that, “I would also like to use this position to explore ways of further supporting our students, particularly recognising the multitude of challenges such as ineffective study skills, financial and mental wellness-related challenges that many of our students face.”

News Archive

UFS study on cell development in top international science journal

2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za
18 September 2008

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