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19 October 2023 | Story Samkelo Fetile | Photo Stephen Collett
Public Management Memorial Lecture
From left; Prof Philippe Burger, Prof Francis Petersen, Premier Mxolisi Dukwana, and Dr Mareve Biljohn.

The University of the Free State (UFS), Department of Public Administration and Management recently hosted its Public Management Memorial Lecture, which was delivered by the Honourable Mxolisi Dukwana, the Premier of the Free State. This year's Public Management Memorial Lecture, titled 'Public Administration and Management as a Method and Tool of Delivering an Ethical, Capable, and Developmental State,' delved into crucial aspects of governance.

In his welcoming address, Prof Francis Petersen, Vice-Chancellor and Principal of the UFS, provided insight into the university's Vision 130 and the university’s strategy, emphasising values such as accountability, social justice, and care. The university’s commitment to engaging on matters of public significance was also highlighted.

Fostering collaboration

Prof Petersen emphasised the importance of collaboration and co-creation – particularly in the post-COVID-19 era – to achieve optimal outputs and outcomes. “The Public Management Memorial Lecture aims to foster collaboration between academia, students, and practitioners in the field of public administration and management.”

In his introduction of Premier Dukwana, Prof Philippe Burger, Dean of the Faculty of Economic and Management Sciences, highlighted Dukwana's role in various government positions, including as the ANC provincial treasurer and, more recently, as the Premier of the Free State.

Addressing challenges and opportunities

In his address, Premier Dukwana acknowledged the need for a collective effort to ensure an ethical, capable, and developmental state, emphasising the challenges faced in the current socio-political landscape. Premier Dukwana acknowledged the need for introspection regarding the state's foundations, values, and mechanisms of service delivery. “Understandably, this is quite an involved and extensive subject that interrogates not only the ethical and capable attributes of the democratic state, but also whether the democratic state is itself developing and evolving towards a horizon that is developmental in outlook.” He stressed the importance of upholding constitutional values and principles, accentuating the need for accountability, transparency, and adherence to the Batho Pele principles.

Premier Dukwana outlined key interventions in the Medium-Term Strategic Framework (MTSF), emphasising the need for a capable and honest government, improved leadership, good governance, and accountability. He called for modernised business processes, improved financial management capability, and participatory local governance mechanisms.

The importance of a social compact was also highlighted, as well as the need to set aside narrow interests for the common goal of long-term growth and development. He stressed the need for a vibrant civil society and underscored the role of public servants in effecting positive change in service delivery.

Reducing bureaucratic red tape

The Premier concluded his address by emphasising the importance of reducing bureaucratic red tape and initiating programmes to streamline service delivery. He expressed optimism for further collaboration with the UFS in strengthening governance and public administration practices. “I am looking forward to having further discussions with the UFS as it relates to the MOU between the UFS and the Free State Provincial Government. The UFS can play a crucial role in helping us to strengthen governance, and specifically improve on public administration and management approaches and practices with the aim of accelerated and improved service delivery.”

The Public Management Memorial Lecture served as a platform for robust discussions on the challenges and opportunities in public administration and management. Premier Dukwana's insights underscored the imperative for ethical, capable, and developmental governance, setting the stage for continued collaboration and engagement on these critical issues.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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