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UFS appoints Prof Paul Oberholster as Dean: Faculty of Natural And Agricultural Sciences

10 October 2023 | Story Lacea Loader | Photo SUPPLIED

The University of the Free State (UFS) has appointed Prof Paul Oberholster as Dean: Faculty of Natural and Agricultural Sciences as of 1 January 2024.

Strong networks and winner of prestigious awards for research, innovation, and leadership

Prof Oberholster is currently the Director: Centre for Environmental Management at the UFS. He completed his undergraduate and postgraduate degrees at the UFS before obtaining a PhD in water resource management at the University of Pretoria.

After several years in secondary education, Prof Oberholster started his scientific research career as a Senior Scientist at the Council for Scientific and Industrial Research (CSIR) in 2007. In 2017, he became a Chief Scientist (the highest scientific position at the CSIR, and senior management) managing large multidisciplinary projects on the African continent related to integrated water resource management and natural-based treatment solutions/ecological engineering.

During his time at the CSIR, he acted as extraordinary professor and lecturer in several academic departments at different institutions, including Stellenbosch University, the University of Pretoria, and the University of the Western Cape. During the same time, he received several prestigious awards for research, innovation, and leadership.

In 2019, Prof Oberholster joined the UFS as Director of the Centre for Environmental Management and also received the National Science and Technology Foundation (NSTF) award in the category Water Research Commission, with a focus on natural-based passive phyco-remediation and phytoremediation treatment technology. In 2022, he was elected as a member of the Academy of Science of South Africa (ASSAf) in recognition of his academic achievements in South Africa, and in 2023 he was appointed as the Managing Director of the Ecological Engineering Institute of Africa (EEIA).

Rated among top 2% in the world in the scientific category of engineering/technology, ecological engineering and environmental engineering.

Currently, Prof Oberholster is rated among the top 2% in the world in the scientific category of engineering/technology, ecological engineering, and environmental engineering. “Prof Oberholster has an extensive and impressive international research standing and has established extensive networks and partnerships. He can lead and manage the faculty in support of the UFS Vision 130’s ultimate intent for the coming years to be a research-led, student-centred, and regionally engaged university,” says Prof Francis Petersen, UFS Vice-Chancellor and Principal.

“It is a privilege to be part of the leadership team in the Faculty of Natural and Agricultural Sciences – we will ensure that the faculty is known nationally and internationally as an excellent faculty serving our community. We aim to consolidate and build on the strengths of the university in order to extend its excellence in research and teaching and learning, which is imbedded in the UFS Vision 130,” says Prof Oberholster.

Prof Oberholster will succeed the current Dean, Prof Danie Vermeulen, who will be retiring at the end of December 2023.

News Archive

Nuclear Medicine on the forefront of cancer research

2017-07-10

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma. The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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