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10 October 2023 | Story Lacea Loader | Photo SUPPLIED
Prof Paul Oberholster
Prof Paul Oberholster, newly appointed Dean of the Faculty of Natural and Agricultural Sciences.

The University of the Free State (UFS) has appointed Prof Paul Oberholster as Dean: Faculty of Natural and Agricultural Sciences as of 1 January 2024. 

Strong networks and winner of prestigious awards for research, innovation, and leadership 

Prof Oberholster is currently the Director: Centre for Environmental Management at the UFS. He completed his undergraduate and postgraduate degrees at the UFS before obtaining a PhD in water resource management at the University of Pretoria. 

After several years in secondary education, Prof Oberholster started his scientific research career as a Senior Scientist at the Council for Scientific and Industrial Research (CSIR) in 2007. In 2017, he became a Chief Scientist (the highest scientific position at the CSIR, and senior management) managing large multidisciplinary projects on the African continent related to integrated water resource management and natural-based treatment solutions/ecological engineering. 

During his time at the CSIR, he acted as extraordinary professor and lecturer in several academic departments at different institutions, including Stellenbosch University, the University of Pretoria, and the University of the Western Cape. During the same time, he received several prestigious awards for research, innovation, and leadership. 

In 2019, Prof Oberholster joined the UFS as Director of the Centre for Environmental Management and also received the National Science and Technology Foundation (NSTF) award in the category Water Research Commission, with a focus on natural-based passive phyco-remediation and phytoremediation treatment technology. In 2022, he was elected as a member of the Academy of Science of South Africa (ASSAf) in recognition of his academic achievements in South Africa, and in 2023 he was appointed as the Managing Director of the Ecological Engineering Institute of Africa (EEIA). 

Rated among top 2% in the world in the scientific category of engineering/technology, ecological engineering and environmental engineering. 

Currently, Prof Oberholster is rated among the top 2% in the world in the scientific category of engineering/technology, ecological engineering, and environmental engineering. “Prof Oberholster has an extensive and impressive international research standing and has established extensive networks and partnerships. He can lead and manage the faculty in support of the UFS Vision 130’s ultimate intent for the coming years to be a research-led, student-centred, and regionally engaged university,” says Prof Francis Petersen, UFS Vice-Chancellor and Principal. 

“It is a privilege to be part of the leadership team in the Faculty of Natural and Agricultural Sciences – we will ensure that the faculty is known nationally and internationally as an excellent faculty serving our community. We aim to consolidate and build on the strengths of the university in order to extend its excellence in research and teaching and learning, which is imbedded in the UFS Vision 130,” says Prof Oberholster. 

Prof Oberholster will succeed the current Dean, Prof Danie Vermeulen, who will be retiring at the end of December 2023. 

News Archive

New research informs improved treatment of brain inflammation
2017-10-13

Description: Sebolai and Ogundeji Tags: Microbiologist, Dr Adepemi Ogundeji,  

Dr Adepemi Ogundeji, researcher in the Department of Microbial,
Biochemical and Food Biotechnology at the
University of the Free State,
and Dr Olihile Sebolai,
her study leader from the same department.
Photo: Charl Devenish



Microbiologist Dr Adepemi Ogundeji has uncovered a new use for an old medicine that can potentially save lives and money. Under the guidance of her study leader, Dr Olihile Sebolai, Dr Ogundeji set out to fight a fungal disease caused by Cryptococcus neoformans. Drs Ogundeji and Sebolai are from the University of the Free State Department of Microbial, Biochemical and Food Biotechnology. 

Dr Ogundeji is passionate about education. “My aim will always be to transfer knowledge and skills in the microbiology field,” she said. “Dr Ogundeji’s study is celebrated in that it found a new purpose for existing medicines. An advantage of repositioning old medicines is by-passing clinical trials, which sometimes take 20 years, and the safety of such medicines is already known,” Dr Sebolai, explained.

Cryptococcus infections are difficult to control and often lead to brain inflammation. In layman’s terms: “Your brain is on fire”. People with HIV/Aids are especially vulnerable, surviving only about three months without treatment. Such patients may present with a Cryptococcus-emergent psychosis, and some with an out-of-control inflammatory condition when initiated on ARVs. 

Dr Ogundeji found that the clinically recommended dosage of aspirin (anti-inflammatory medicine), and quetiapine (anti-psychotic medicine) is sufficient to control the infection. Her exceptional work was readily published in some of the foremost journals in her field, namely, Antimicrobial Agents and Chemotherapy and Frontiers in Microbiology

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