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03 October 2023 | Story André Damons | Photo André Damons
Dr Asha Malan
Dr Asha Malan, Head of Vascular Surgery in the Faculty of Health Sciences at the University of the Free State (UFS), was elected as the President-elect for the Vascular Society of Southern Africa – the first woman in South Africa to be elected for this position in the Society’s 40-year existence.

Dr Asha Malan, the Head of Vascular Surgery in the Faculty of Health Sciences at the University of the Free State (UFS), has made history by being elected as the President-elect for the Vascular Society of Southern Africa. This milestone marks the first time a woman in South Africa has attained this prestigious position in the Society’s 40-year existence.

Dr Malan, an exemplary surgeon and a trailblazer, is not only one of the seven qualified female vascular surgeons in the country but also holds the distinction of being the youngest and first female to head an academic unit in South Africa. Her election took place at the recently concluded 2023 Vascular Society of Southern Africa (VASSA) Congress, a significant event for the UFS Division of Vascular Surgery, under her leadership as the congress chairperson. The Congress was hosted at the Lord Charles Hotel in Somerset West, Cape Town, in collaboration with the World Federation of Vascular Societies (WFVS) and the European Society of Vascular Surgery (ESVS).

Reflecting on her achievement, Dr Malan remarked, “It is not only an honour to be the first woman in 40 years to lead this Society, but an honour to be elected for this role.  VASSA has established a well-recognised international footprint and has invested significantly in promoting the growth of vascular surgery as a specialised surgical field in South Africa.” 

She added, “Representing the Society in this capacity allows me to continue serving its members and the Southern African community, creating awareness not only about the growing burden of vascular diseases but also the advancements in the field to address these challenges.” 

First gathering since 2018

The 2023 VASSA Congress marked the first gathering of Vascular Surgery specialists in South Africa since 2018, a gap caused by the pandemic. The event was attended by approximately 300 delegates, including nursing staff, radiographers, vascular technologists and other allied health professionals with a keen interest in Vascular Surgery. VASSA sponsored nursing staff, a radiographer and a vascular technologist from Universitas Academic Hospital to attend the meeting. 

The high-quality, four-day programme featured talks from local and international experts covering various aspects of vascular surgery, such as aortic surgery, peripheral arterial disease, carotid pathology, dialysis access and venous disease.  Notably, the academic programme saw the participation of 32 international speakers. Guest speaker, Dr Imtiaz Sooliman, the founder of the Gift of the Givers Foundation, delivered an inspiring talk during the ethics session titled “Humanitarian efforts within the Healthcare Sector – Sharing the Responsibility”.  

Presentations

During the Congress, Dr Malan and several Vascular Surgeons from the Department of Surgery represented the UFS. Dr Malan shared her experiences in developing a dedicated unit for the management of complex thoraco-abdominal aneurysmal disease, a talk that garnered significant interest and applause from both local and international experts. 

In her presentation, Dr Malan took the audience through her journey to several different international units to gain expertise in open thoraco-abdominal aortic surgery. She also highlighted the UFS Division of Vascular Surgery’s achievement of being the first academic Vascular Surgery unit in South Africa to perform a complex endovascular aortic aneurysm repair.  In addition, Dr Sam Letsoara and Dr Wikus Mulder, Vascular Surgery Fellows in training, presented the local evolution of endovascular therapy as well as an audit of endovascular management of blunt thoracic aortic injury at Universitas Academic Hospital, respectively.  Dr Sam Agbo, a registrar in the Department of Surgery, also presented his MMed research, evaluating the cost of open versus endovascular management of abdominal aortic aneurysms.

The Congress significantly contributed to the promotion of Vascular Surgical awareness and care, not only in South Africa, but across Africa and globally. It stands as a testament to the dedication and expertise of the Division of Vascular Surgery at the University of the Free State.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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