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High Court Tour
The Free State High Court hosted a Women's Month educational tour for UFS female students.

"It is significant to reflect that it was just more than 100 years since women were allowed to practice law. The first female legal practitioners being admitted in the early 1920s. A celebration of Women's Month acknowledges the many victories for equality and social justice that women practising in the legal profession have contributed and continue to contribute," said Dr Anthea-Lee September-Van Huffel, Private Law Lecturer in the University of the Free State (UFS) Faculty of Law, as she reflected on the importance of commemorating Women's Month.

To conclude the celebration, the faculty collaborated with the Free State High Court to organise a tour, affording a group of UFS female students the opportunity to immerse themselves in the practical aspects of civil litigation by observing court proceedings in the Free State High Court.

A glimpse into the legal world

The students engaged with judges, advocates, and attorneys, addressing challenges confronting the legal profession, including issues related to mental health post-qualification. Judge Nokuthula Daniso emphasised during the proceedings, "A career in the legal profession is highly demanding. Your passion, proficiency, and diligence are your armour."

Salomie Kichele, a third-year Law student, was among the participants of the tour. She described the experience as the highlight of her year, saying, "Observing the intricacies of the legal system, from courtroom processes to the dynamics between judges, attorneys, and others, was truly fascinating. However, what truly stood out was gaining access to the judge's chamber, a privilege that is usually restricted. Being able to engage the judge with questions about her journey to becoming a judge, especially as a woman, was inspirational. Being inside the judge's chamber, surrounded by South African law books, highlighted the level of expertise required of our judges when dealing with cases. This experience further motivated me to continue nurturing my passion for reading."

Bridging the Gap Between Theory and Practice

For Kichele, this exposure to the High Court and interaction with judges, advocates, and attorneys provided clarity regarding the expectations placed upon her as a future legal practitioner. It bridged the gap between theoretical knowledge acquired in the classroom and the practical application of the law. By witnessing real cases and observing legal professionals in action, Law students gain a deeper understanding of the legal system's intricacies and the nuances of courtroom dynamics.

"Such exposure helped me identify the specialisation I would like to pursue in the legal field and fuelled my determination to pursue it. Furthermore, being within the High Court environment highlighted the need for more female judges. Experiencing this can serve as a motivating force for women aspiring to become judges one day," Kichele added. 

Bloemfontein's legal legacy

The UFS Faculty of Law enjoys an advantageous location in Bloemfontein, renowned as a central hub for numerous high-profile legal cases, primarily because it houses the Supreme Court of Appeal. Furthermore, the faculty takes pride in the fact that several of its academic staff members have, over the years, served as acting judges in the Bloemfontein High Court. Consequently, the Faculty of Law remains dedicated to nurturing and fortifying its ties within the legal profession. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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