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22 September 2023 | Story Supplied | Photo Supplied
Mogotsi
Milton Mogotsi, a PhD student in Medical Virology, won the Dr Lehlohonolo Mathengtheng Trophy at the Faculty of Health Sciences’ Faculty Research Forum.

Milton Mogotsi, a PhD student in Medical Virology, was awarded the Dr Lehlohonolo Mathengtheng Trophy at the recently held Faculty of Health SciencesFaculty Research Forum

Mogotsi was the recipient of the trophy for best presentation by a PhD student in the laboratory category. He is supervised by Prof Martin Nyaga, Associate Professor in the Division of Virology and Head of UFS-NGS Unit, and co-supervised by Prof Trudi O’Neill, Professor in the Department of Microbiology and Biochemistry.

The Research Forum offers staff members and postgraduate students an opportunity to present the results of their research. The Faculty Research Forum aims to provide a platform to disseminate outputs and findings of all the research conducted in the faculty, and to also provide junior researchers/postgraduate students exposure.

Results of his study 

Mogotsi presented the results of his PhD study titled “Longitudinal gut virome analysis provides insights into early gut colonisation and temporal dynamics in paediatric subjects from the Free State Province, South Africa”. His research sought to understand the longitudinal evolution of viruses colonising the gastrointestinal tract of infants during their first year of life. In this study, metagenomic next generation sequencing was performed on faecal specimens collected longitudinally from a cohort of 17 infants during their first six months. These infants were recruited from three public hospitals around Bloemfontein after consent was attained from the mothers. 

The results of this study revealed that the guts of infants are highly colonised by diverse and dynamic viral communities, formed by a richness of different viruses infecting humans, predominantly those that are associated with gastroenteritis in children. These pathogenic agents were detected as early as one day old and increasing in abundance and diversity over time, even in the absence of clinical manifestations. 

The detection of such pathogenic viruses highlights the importance of screening for intestinal pathogens at an early age to close existing gaps and enhance the effectiveness of current treatment. In addition, the detection of viruses of unknown origin in faeces of infants underscores the need to extend sampling to mothers to better understand transmission patterns of such pathogens. Importantly, interventions to improve water quality, sanitation, and hygiene at the household level would be very impactful in minimising viral transmissions to infants and reducing the high childhood morbidities and mortalities in Africa.

A great honour

“As an emerging research virologist, presenting at such forums provides me with a platform to introduce my research, but also presents the opportunity to initiate discussions with other researchers, and exchange ideas that can help improve my future scientific approaches,” says Mogotsi. 

“Being awarded the Dr Lehlohonolo Mathengtheng Trophy is such a great honour, and it came at the right time when I’m near completion of my PhD. It has really motivated me to work even harder and make sure I obtain this qualification. However, this would not have been possible without the guidance and support from my supervisor, Prof Nyaga. I want to thank him for giving me the opportunity to conduct this research project under his supervision. The continued support and encouragement from my colleagues in the UFS-Next Generation Sequencing Unit is also highly appreciated,” he concludes.

Mogotsi is finalising the write-up of his PhD thesis which he will be submitting in November 2023 for examination and is also preparing manuscripts for submission in high-impact internationally recognised peer-review journals. 

Other winners:

  • John van der Riet Medal Winners

Robyn Smith, Veronica Ntsiea, Stephen Brown, and Joanne Potterton, Department of Physiotherapy, School of Health and Rehabilitation Sciences, UFS.

Pre-operative neurodevelopmental assessment in young children undergoing cardiac surgery in central South Africa: feasibility and clinical value.

  • Muller Potgieter Medal Winners

Johannes van den Heever, Christiaan Jordaan, Angelique Lewies, Dreyer Bester, Jacqueline Goedhals, Lezelle Botes, Pascall Dohmen, and Francis Smit, Department of Cardiothoracic Surgery, School of Clinical Medicine, UFS.

Comparison of the function and structural integrity of cryopreserved pulmonary homografts versus decellularised pulmonary homografts after 180 days implantation in the juvenile ovine model.

  • Kerneels Nel Medal Winners 

Lizemari Hugo-Van Dyk, Champion Nyoni, Margaret Williams, and Benjamin Botha, School of Nursing, UFS.

Preceptor support during the COVID-19 pandemic: Recommendations for continuing development.

News Archive

The failure of the law
2004-06-04

 

Written by Lacea Loader

- Call for the protection of consumers’ and tax payers rights against corporate companies

An expert in commercial law has called for reforms to the Companies Act to protect the rights of consumers and investors.

“Consumers and tax payers are lulled into thinking the law protects them when it definitely does not,” said Prof Dines Gihwala this week during his inaugural lecture at the University of the Free State’s (UFS).

Prof Gihwala, vice-chairperson of the UFS Council, was inaugurated as extraordinary professor in commercial law at the UFS’s Faculty of Law.

He said that consumers, tax payers and shareholders think they can look to the law for an effective curb on the enormous power for ill that big business wields.

“Once the public is involved, the activities of big business must be controlled and regulated. It is the responsibility of the law to oversee and supervise such control and regulation,” said Prof Gihwala.

He said that, when undesirable consequences occur despite laws enacted specifically to prevent such results, it must be fair to suggest that the law has failed.

“The actual perpetrators of the undesirable behaviour seldom pay for it in any sense, not even when criminal conduct is involved. If directors of companies are criminally charged and convicted, the penalty is invariably a fine imposed on the company. So, ironically, it is the money of tax payers that is spent on investigating criminal conduct, formulating charges and ultimately prosecuting the culprits involved in corporate malpractice,” said Prof Gihwala.

According to Prof Gihwala the law continuously fails to hold companies meaningfully accountable to good and honest business values.

“Insider trading is a crime and, although legislation was introduced in 1998 to curb it, not a single successful criminal prosecution has taken place. While the law appears to be offering the public protection against unacceptable business behaviour, it does no such thing – the law cannot act as a deterrent if it is inadequate or not being enforced,” he said.

The government believed it was important to facilitate access to the country’s economic resources by those who had been denied it in the past. The Broad Based Economic Empowerment Act of 2003 (BBEE), is legislation to do just that. “We should be asking ourselves whether it is really possible for an individual, handicapped by the inequities of the past, to compete in the real business world even though the BBEE Act is now part of the law?,” said Prof Gihwala.

Prof Gihwala said that judges prefer to follow precedent instead of taking bold initiative. “Following precedent is safe at a personal level. To do so will elicit no outcry of disapproval and one’s professional reputation is protected. The law needs to evolve and it is the responsibility of the judiciary to see that it happens in an orderly fashion. Courts often take the easy way out, and when the opportunity to be bold and creative presents itself, it is ignored,” he said.

“Perhaps we are expecting too much from the courts. If changes are to be made to the level of protection to the investing public by the law, Parliament must play its proper role. It is desirable for Parliament to be proactive. Those tasked with the responsibility of rewriting our Companies Act should be bold and imaginative. They should remove once and for all those parts of our common law which frustrate the ideals of our Constitution, and in particular those which conflict with the principles of the BBEE Act,” said Prof Gihwala.

According to Prof Gihwala, the following reforms are necessary:

• establishing a unit that is part of the office of the Registrar of Companies to bolster a whole inspectorate in regard to companies’ affairs;
• companies who are liable to pay a fine or fines, should have the right to take action to recover that fine from those responsible for the conduct;
• and serious transgression of the law should allow for imprisonment only – there should be no room for the payment of fines.
 

Prof Gihwala ended the lecture by saying: “If the opportunity to re-work the Companies Act is not grabbed with both hands, we will witness yet another failure in the law. Even more people will come to believe that the law is stupid and that it has made fools of them. And that would be the worst possible news in our developing democracy, where we are struggling to ensure that the Rule of Law prevails and that every one of us has respect for the law”.

 

 

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