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05 September 2023 | Story Leonie Bolleurs | Photo Supplied
Prof Lesley Green
Prof Lesley Green was announced the winner of the 2023 ASSAf Humanities Book Award in the category ‘Established Researcher’. She delivered a lecture on her book: Rock. Water. Life: Ecology and Humanities for a Decolonial South Africa.

A group of more than 100 academics and students from universities across South Africa and abroad attended the virtual lecture by Prof Lesley Green, winner of the 2023 ASSAf Humanities Book Award in the category ‘Established Researcher’, who discussed her cross-cutting book, titled: Rock. Water. Life: Ecology and Humanities for a Decolonial South Africa. 

The lecture is part of a series focused on the Humanities Book Awards, offering award recipients a platform to discuss the motivation behind their books, the societal impact of their work, and the personal influences that shaped their text. Prof Reddy said that academics and students can anticipate a series of humanities book award lectures in the coming months. 

Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation at the University of the Free State (UFS), member of the Academy of Science of South Africa (ASSAf), and member of the Book Award adjudication panel, facilitated the recent (29 August 2023) online 2023 ASSAf Humanities Book Award Lecture. 

Prof Green, Professor of Anthropology and the Director of Environmental Humanities South (EHS) at the University of Cape Town, was announced the winner of the 2023 ASSAf Humanities Book Award in the category ‘Established Researcher’, for which ASSAf received 31 nominations. She received the award at the end of March this year during a ceremony at the Vineyard Hotel in Cape Town.

The first ASSAf Book Prize was awarded in 2017, and since then ASSAf has conferred the award on an individual every two years to recognise and celebrate the significance and impact of well-written scholarly writings on human knowledge and intellectual efforts in South Africa. 

Prof Reddy characterised Prof Green's specific work as an outstanding book that makes a formidable contribution to the field.

Justice-based environmental sciences 

Prof Green’s research centres on justice-based environmental sciences in South Africa, with a particular focus on the relationship between knowledge and democracy in the Global South – a central theme in her award-winning text.

In the three parts of her book, ‘Past Present’, ‘Present Futures’, and ‘Futures Imperfect’, Prof Green explores the interwoven nature of the past, present, and future. Within these three parts, she delves into the fascinating array of identity markers, inequality, racism, colonialism, and environmental destruction in South Africa. 

Prof Reddy noted that the text asserts a need for environmental research and governance to evolve, contributing to addressing South Africa’s deep history of racial oppression and environmental exploitation. “The book also offers an in-depth engagement of environmental conflict, shedding light on matters often overshadowed by daily concerns in contemporary South Africa,” he added. 

The book, linking the humanities and social sciences with the natural sciences and applied sciences, touched on an array of important topics, including the history of contested water access in Cape Town, struggles over fracking in the Karoo, the call for the decolonisation of science (#ScienceMustFall), land restitution versus the politics of soil, contests over baboon management, and the consequences of sending sewage to urban oceans. 

Prof Green has observed the landscape of environmentalism for a couple of years and noticed a series of struggles. “Typically, these conflicts were being presented in highly polemic ways, often showcasing tremendous tension between academic environmentalism and activists on the ground. I noticed recurring patterns – what was being presented as the preferred form of environmentalism was not something I could support. For example, the frack-free Karoo campaign. It left me quite uncomfortable due to the erasure of Khoi and San presence in the Karoo,” she added. 

“So, what kind of environmentalism could I get behind? Questions around a just environmental governance begin to arise for me.”

Property, #ScienceMustFall, and black environmentalism 

During the discussion, Prof Green shared particular images from each section of her book that caused her to pause and reconsider her stance on the type of environmentalism she could support.

“We inherited a way of thinking about the world that was separated from nature and society. We have challenged that division of nature and society in respect of race and racism and sex and sexism, but we have not brought that critique to bear on how we relate to the world. Somehow, under neo-liberal governance, we find ourselves in this space where economics and finance are seen as the hero that will bring it all together. 

These comments merely scratched the surface of Prof Green’s insights into her book – which Prof John Higgins, Emeritus Professor who formerly held the Arderne Chair in Literature at the University of Cape Town (now Senior Research Scholar at UCT), referred to in his closing remarks as a rich description of a magnificent book. According to him, this scholarly book not only circulates and makes knowledge public, but also provides an opportunity to question that very knowledge. 

This marked the first instance where ASSAf combined book selection with a discussion on the chosen book, underscoring the value of scholarly literature.

- In the Emerging Researcher category, Dr Rick de Villiers from the UFS Department of English was a shortlisted candidate for his book, titled: Eliot and Beckett’s Low Modernism: Humility and Humiliation. 

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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