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18 April 2024 | Story Leonie Bolleurs | Photo Stephen Collett and Leonie Bolleurs
Left: Wikus Vorster is the Dean’s Medal winner in the final-year third-year curriculum. He completed his BSc Actuarial Science degree. Pictured with him is the Dean of the Faculty of Natural and Agricultural Sciences, Prof Paul Oberholster. Right: Mienke Botha completed the BScAgric Animal Science programme. She received the Dean’s Medal for the best grades in the final-year fourth-year curriculum.

A total of 1 582 students graduated in the Faculty of Natural and Agricultural Sciences at the April graduation ceremonies of the University of the Free State (UFS). The faculty honoured four students for achieving the best results in respectively the third-year curriculum, the fourth-year curriculum, final-year honours, and final-year master’s.

Dr Snowy Khoza, a seasoned non-executive, senior adviser, acknowledged strategist, and development activist in the infrastructure development space, addressed the graduates in the first two sessions of the day.

She urged graduates to remember that graduation is not just an end, but a new beginning – a launching pad for future endeavours and aspirations. “Whether you choose to pursue further studies, embark on a career in research, industry, or entrepreneurship, or devote yourself to making a difference in your community, know that the world is ripe with possibilities waiting to be explored.”

Dr Khoza sponsored R50 000 to each Dean’s Medal recipient from the first two graduation ceremonies of the day.

Actuarial Science right up my alley

Wikus Vorster, who completed his BSc Actuarial Science degree, received the Dean’s Medal in the final-year third-year curriculum in the Faculty of Natural and Agricultural Sciences. He was also awarded the Senate Medal for achieving the highest weighted average across all undergraduate and postgraduate qualifications in all faculties of the UFS. Vorster, who has always had a love for numbers and programming, says it is truly an honour to see his hard work recognised in this way.

“Actuarial Science always seemed to be right up my alley since it combines all my favourite academic interests,” he says. According to him, every module had something to offer.

His strategy for academic success was to put in an enormous amount of hard work and sacrifice. The support from family and friends also helped him to perform at his best.

Vorster aspires to become the best-qualified actuary he can by continuing to develop his understanding of risk, programming, and statistics.

Give your best at all times

Mienke Botha, who grew up on a farm in an agriculturally driven community, surrounded by truly passionate farmers, completed the BScAgric Animal Science programme. She received the Dean’s Medal for the best grades in the final-year fourth-year curriculum. About receiving this honour, Botha says, “I never really worked that hard just for the recognition; on the contrary, I truly enjoyed it.”

She continues, “I find my Animal Nutrition, Animal Physiology, and Animal Breeding subjects rewarding in my third and fourth year. I love how they all integrate into each other and how they can be applied together in the practical industry. It also helps to fully understand the science and to base farming decisions on this.”

Her approach to success is to give her best at all times. She believes that discipline is one aspect of life that will carry over to all others. Moreover, she states, “I always strived to use the abilities and talents I have received from the Lord to the fullest.”

Having experienced the satisfaction and happiness that work in this field can bring, Botha comments that she would like to quality as a ruminant nutritionist, focusing on the dietary needs and feeding management of animals, such as cattle, sheep, and goats.

The little we know about the small things in life

Rinus Behrens completed his BSc Honours in Food Science and was awarded the Dean’s Medal for achieving the best results in the final-year honours class. He says that with the talents that God gave him, he aimed from the beginning to do only his best.

He believes that if one truly has an interest in the work you are doing, you should be excited to talk about it. “You will not only gain more knowledge; studying will also become easier.” During his studies, the subjects of Food Microbiology and Meat Science specifically stood out for Behrens. “My research on crocodile meat – regarding the microbial and physio-chemical aspects thereof – required me to use the knowledge obtained from those subjects as a whole to fully understand what may have led to the results I obtained. Both of these subjects opened my eyes in terms of how little we really know about the small things in life. Something as small as the smallest bacteria can have such a major influence on our lives. As scary as it seems, it excites me!”

Behrens is of the opinion that Food Science influences everyone, even if you don’t know it. “We all eat food, and getting behind the science of it all is what truly excites me. This is where I feel I can have the greatest impact on many people's lives while enjoying every moment of what I am doing.”

Future steps for him after completing his PhD are to pursue a career in research microbiology, food auditing, or further research based on the microbiology of crocodile meat.

Theory of Architecture – changing the way I see and think about architecture

The Dean’s Medal for the final-year master’s class went to an Architecture student, Arran Wood. It is the role his lecturers played in his success that stood out to him. “I am grateful for the amazing support and encouragement I’ve received over the years from my lecturers, who spent so much of their own effort into teaching me what I know about architecture,” he comments.

Both of his parents are in the building industry; his father worked in construction and design and his mother as a civil engineer. “Even though it was always my decision, growing up I gained a passion to work in these fields and that is why I chose architecture,” he says.

During his studies, it was especially Theory of Architecture that fascinated him. “It changed the way I see and think about architecture and even about life,” he remarks.

Just like the other medal winners, Wood also believes that hard work played a key role in his success. Hard work, late nights, and never giving up was his strategy when studying. 

For the future, he hopes to make a difference and bring meaning to the work he does. “I care deeply about South Africa and the people in it,” he concludes. 

NAS Medalists 2024

Left to right: Rinus Behrens completed his BSc Honours in Food Science and was awarded the Dean’s Medal for achieving the best results in the final-year honours class, while an Architecture student, Arran Wood, received the Dean’s Medal for the final-year master’s class.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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