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19 April 2024 | Story André Damons | Photo Stephen Collett
Prof Salim Karim
Prof Francis Petersen, Vice-Chancellor and Principal of the University of the Free State (left) and Prof Gert Van Zyl, Faculty of Health Sciences Dean (right) conferred Prof Salim S Abdool Karim honorary doctorate for his ground-breaking research in AIDS and COVID-19. He received the degree PhD in Medical Virology (h.c.) during the Faculty of Health Sciences graduation ceremony.

With the case study of Caprise 256, a young woman in his AIDS study, and her potent antibody that kills HIV, Prof Salim S Abdool Karim, honorary doctorate recipient, conveyed the message of the power of science, knowledge and discovery to motivate the graduates from the Faculties of Health Sciences and Theology and Religion at the University of the Free State (UFS).

Prof Karim, renowned for his ground-breaking research in AIDS and COVID-19, received the degree PhD in Medical Virology (h.c.) during Thursday’s (18 April 2024) graduation ceremony.

From humble beginnings

“It is great honour and privilege to be here and accept this honorary doctorate. I first went to university in 1978 and wanted to study engineering but did not have the money to pay for registration as I come from a poor background. So, I attended classes anywhere. But then I was accepted to study medicine at the University of Natal with a full scholarship and that was the end of my career in engineering.

“From that humble beginning to today where you might have watched me on TV trying to share with you what we know about COVID-19 and other infectious diseases, is a great culmination of a career and I am deeply honoured and privileged to receive this honorary doctorate”, he said shortly after accepting his fifth honorary degree.

Prof Abdool Karim, a clinical infectious disease epidemiologist who is widely recognised for scientific contributions to AIDS and COVID-19, also shared with graduates the last 20 years of his academic journey with an example to illustrate how exciting the acquisition of knowledge and thrill of discovery can be. He talked about his work with AIDS and says it remains one of the world’s greatest challenges. Last year, he said, there were 1.3 million new infections and over 700 000 deaths as a result of AIDS.

Caprisa 256’s antibody

“I have devoted almost 40 years of research to looking for solutions for the AIDS problem and one of the biggest problems we are dealing with is the high rate of HIV, particularly in young girls. In 2003 we started a study to begin to understand why young women are at such a high risk of HIV.

“We enrolled hundreds of young women without HIV. We provided them with all kinds of knowledge to try and keep them HIV-free. Amongst those women we enrolled was participant 256, a young lady and she acquired HIV infection two years later in 2005.”

It would later turn out that this young woman, codename Caprisa 256, has a very special antibody – the kind that can kill a wide range of HIV – which is referred to as a broadly neutralising antibody. It is an antibody researchers tried to ellicit in making vaccine.

It turned out that not only is her antibody able to kill a wide range of HIV, it is a highly potent antibody. After testing and cloning a cell in the blood and growing it in a culture and harvesting the antibody, it was genetically manipulated to get a better antibody.

The Director of the Centre for the AIDS Programme of Research in South Africa (Caprisa), explained that it took two-and-a-half years to manufacture this antibody in the US and the first South African was injected with it in 2020. They enrolled over 1 000 women in a study with half of the women receiving the placebo and half the antibody. The question whether it works, or protects humans from the HIV will only be answered next year, Prof Abdool Karim explained. 

The 3 Ps

“What I am trying to convey to you, it’s the power of science, the power of knowledge, the power of discovery and when each of you goes out into the world, I want to leave you with the message that there are three valuable lessons that I have learned in this 20-year journey of Caprisa 256.

“The first one is find your passion, find something that excites you when you wake up in the morning. There will be people that would want to pull you down, you will have to stand firm. You have to show that you are passionate and committed and regardless of the obstacles, you will persevere. Find your passion and persevere. And as you do that, always remember the pursuit of excellence. I know that each of you will bring to this world your own humanity, your own values, and we are in this world, in a situation where we are in desperate need of people who will bring their humanity and their wisdom to bear.”

Prof Francis Petersen, Vice-Chancellor and Principal of the UFS, congratulated Prof Abdool Karim on his honorary degree and praised his groundbreaking research on Aids and COVID-19, as well as his exceptional work in medical virology over the years. “Prof Abdool Karim led the South African response to COVID-19, providing us as the public, as well as the government with scientific advice on the virus, new variants, and flattening the curve. Prof Abdool Karim has the ability to easily explain complex science to members of the general public in such a way that they are able to understand it. He played a critical role during the pandemic, and for this as well as for his research on Aids, South Africa is indebted to him.

News Archive

Unique programme for next generation of professors launched
2010-11-19

Some of the scholars taking part in the Vice-Chancellor's Prestige Young Scholars Programme are, from the left: Dr Andréhette Verster, Ms Liezel Kotzé and Dr Nthabeleng Rammile.
Photo: Stephen Collett

The University of the Free State (UFS) has launched a programme that will provide an accelerated pathway to 25 young scholars with recent PhDs and teach them how to become professors through intensive local and international mentorship, research support and academic training.

The Vice-Chancellor’s Prestige Programme for Young Scholars focuses on the next generation of top researchers in South Africa who will fill the gap left by retiring academics. It will also add significantly to the diversity of the professoriate at the UFS.

No other university in the country has a programme of such scale and intensity for building excellence and diversity through young scholars.

“The programme is highly selective and limited to the most promising young scholars at the university. It will also contribute towards establishing an international reputation for the university and positioning the UFS as one of the best research institutions in the country,” said Prof. Neil Roos, Director of the Postgraduate School at the UFS. He will manage the programme together with Prof. Jackie du Toit, also from the university.

Running for the next three years, the programme will put the 25 scholars through an intensive programme of academic and scholarship support which includes advanced theoretical and methodological training and exposure to leading international scholars in their fields. They will also be exposed to intensive reading and writing programmes, high-level seminar and conference participation and presentation, accelerated publication schedules and personal mentoring and advising plans.

“Scholarship will only grow if there is a critical mass – and this is what we want to achieve at the UFS. We want to create a pool of young scholars, develop and connect them with international scholars and place them at top universities in the world where they can be mentored by the best in their respective fields,” said Prof. Jonathan Jansen, Vice-Chancellor and Rector of the UFS at the launch of the programme.

According to Prof. Jansen, the UFS aims to draw public intellectuals and A-rated scientists to the campus and make academic work attractive to academics at the university and countrywide.

The group of scholars has a good academic record, with 69% of them completing their PhDs within the last five years. The group is well represented in terms of race and gender; the majority are in the 26 to 30-year age group and specialisations include the social sciences (including education, the humanities and arts) as well as the natural sciences.

“Scholarship develops over time. We are proud and extremely honoured to be selected for this prestigious programme. With this scholarship we acknowledge the responsibility of building the UFS and of extending our knowledge across disciplines. We will establish a scholarly advancement for our university that will enable it to compete with the best in the world,” said Dr Nalize Marais, one of the prestige scholars.

The launch was also attended by members of the university’s International Advisory Council (IAC). This council, which visited the university the past week to advise the leadership on its future positioning strategies, especially in relation to its international aspiration to become a place of scholarship and service among the leading universities in the world, congratulated the UFS on this groundbreaking programme.

“You are lucky to have a leadership that dares to dream and that can act the dream. You are fortunate that your leadership wants to take this university forward and explore new horizons,” said Prof. Aki Saweyrr, former Secretary-General of the Association of African Universities in Ghana and member of the IAC.

Ending the evening’s programme was Dr Gansen Pillay, Vice-President of the National Research Foundation. Prof. Gansen also congratulated the UFS on its visionary and inspirational leadership. “It is a privilege to make a life-changing contribution to research in the world. Universities must take ownership of their own development – which is exactly what the UFS is doing. And, although this is a truly South African programme, it could have an impact on the rest of the world,” he said.
 

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