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04 April 2024 | Story Leonie Bolleurs | Photo Stephen Collett
Prof Frank Zachos
Prof Frank Zachos recently delivered his inaugural lecture on the UFS Bloemfontein Campus.

Prof Frank Zachos, a scientist and Head of the Mammal Collection at the Natural History Museum (NHM) in Vienna – one of the world’s largest natural history museums – recently delivered his inaugural lecture at the University of the Free State (UFS) on the Bloemfontein Campus.

His lecture was titled: Of bat bombs and super moms – the wondrous and wondrously curious world of mammals.

Prof Zachos, an affiliated researcher at the UFS, says he chose mammals as the topic of his lecture because he is a mammalogist and curator of mammals at the Natural History Museum. Additionally, he collaborates with Prof Paul Grobler, Head of the Department of Genetics, on mammal projects.

Exposure to almost unparalleled biodiversity in SA

With a mixture of entertaining fun facts and some proper research results, he presented his lecture, providing an overview of some of the most interesting aspects of mammals. These included their different ways of reproduction: the platypuses laying eggs, the tiny marsupial offspring growing in a pouch, and placental mammals having long gestation times. Furthermore, he compared levels of biodiversity in South Africa and Europe and highlighted some particularly bizarre mammals, such as the aye-aye, naked mole-rat, the platypus, and two extinct South African ungulates from their collection in Vienna – the quagga and the blue antelope.

Prof Zachos also discussed his own research on blue antelope genetics, as well as research on other species, in the context of the detrimental impact humans have on mammals and other wildlife.

Moreover, his lecture included a reference to Project X-Ray, a story of how the US army pursued an unsuccessful plan to use bats as carriers of mini bombs in World War II.

Prof Zachos, who is specifically known for his research on the systematics, biogeography, and genetics of red deer, as well as his theoretical work on the species problem (‘what is a species?’ –  one of the most hotly debated topics in evolutionary biology), is affiliated with the UFS due to his longstanding collaboration with Prof Grobler. He says they have known each other for a long time, have published together, and that he has also served as an external reviewer for several theses coming from the Department of Genetics.

“Apart from this personal connection, what made this collaboration particularly interesting to me from a professional viewpoint, is the rich wildlife biodiversity and the research focus of Prof Grobler’s research group, which overlaps significantly with my own longstanding interests,” adds Prof Zachos.

“Working with Prof Grobler, I am involved in studies on the genetic diversity and structuring of different mammal species occurring in South Africa. The opportunity to spend time in the field for sample collection and other activities is definitely also a highlight,” remarks Prof Zachos.

Ideal combination of academic and personal growth

Regarding his connection with the UFS and its impact on shaping the future direction of his research, he states that he has a strong interest in antelopes – a group of mammals not found in Europe, but very prominent in South Africa. “Apart from that, people in the Department of Genetics have expertise in relevant areas that I personally do not have, for example bioinformatics. For me, it is the ideal combination of academic and personal growth, and I am very grateful to have this unique opportunity.”

He believes that his affiliation with the UFS and its Department of Genetics will continue to provide him with opportunities to expand his research and knowledge to different species and ecosystems.

Beyond science, he says that he has developed an interest in the country as well. “I have been reading books about South Africa, and I consider myself very privileged to have a second academic home here, which gives me the opportunity for exchange with people of different backgrounds,” he comments.

News Archive

Researchers focus on parrots, poultry and phage therapy
2014-10-10

Photo: en.wikipedia

Veterinary biotechnology focuses on microbial and molecular biological approaches to veterinary illnesses. The group working on veterinary biotechnology research at the University of the Free State (UFS) consists of two academic staff members, Prof Rob Bragg and Dr Charlotte Boucher, two post-doctoral fellows, Drs Chris Theron and Arina Hitzeroth, five PhD and three honours students.

The group has three research focus areas.

Dr Boucher says, “Our main focus area is infectious coryza in poultry, caused by the bacterium Avibacterium paragalliarum. The aim is the control of the disease, mainly through improvement of vaccines, understanding the immune response and improved biosecurity. A key objective is improving methods for serotyping; studying of selected surface antigens and investigating the influence recently discovered bacteriophages might have on virulence. We have co-operative projects with research groups in China, India and Israel.

“The second focus area is an expression system co-developed with the National Institute for Agronomic Research (INRA), France. The flagship project is the expression of the coat protein gene of the beak and feather disease virus, a disease affecting parrots, currently threatening the endangered Cape parrot. This system has led to the development of serological tests, currently under patenting. The application of this system has been extended to human-related diseases, with two interdisciplinary projects underway, co-working with Profs Muriel Meiring and Felicity Burt. Prof Meiring is working on diseases causing bleeding disorders, such as blood-clotting impairment, while Prof Burt is working on viral infections causing haemorrhagic (bleeding) disorders.

“We are also researching disease control in a post-antibiotic era, investigating the potential of phage-therapy by targeting and destroying pathogenic islands within a host, with reduced side-effects on the host itself.

“We have smaller projects, including an interdisciplinary project with Zoology, looking at the protein profile of amphibian (frog) secretions with the focus on antimicrobial activity, as these secretions assist with protecting amphibian skin against infections.”  


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