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18 April 2024 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Nkosingiphile Zondi
Nkosingiphile Zondi graduated with a BAgric Mixed Farming degree. In March, he also released his first music album, Ngingohlakaniphile.

If you have ever browsed music on YouTube, Spotify, or Apple Music and came across the 15-track album, Ngingohlakaniphile, you would never have guessed that the young man on the cover – dressed in light colours of grey and white – has another passion: farming.

Nkosingiphile Zondi, hailing from a small rural area called Tugela Ferry in KwaZulu-Natal, graduated with a Bachelor of Agriculture, majoring in Mixed Farming Management, at the April graduation ceremonies of the University of the Free State (UFS).

According to Zondi, his love for nature, animals, and their well-being motivated him to pursue a degree in mixed farming.

Two milestone events in one month

Zondi, who describes himself as open to new ideas, hardworking, and someone who values respect (something his parents taught him), says he is excited and grateful for achieving two milestones: obtaining his degree and releasing his first album, both within a month's time (his album was released on 22 March 2024). “I have never been so happy in my life,” he remarks.

Regarding balancing farming and music in the future, he says it won't be a problem because he managed to do both in the past few years. Dr Phumudzo Tharaga, Lecturer in Agrometeorology in the Department of Soil, Crop, and Climate Sciences, says that Zondi managed to graduate in record time while pursuing his music career. “This is a unique talent,” he comments.

He believes that his music will help people see life from a different perspective. “Life is not only about struggles. There's also happiness after struggling. I hope that my music can heal people, ease the pain at times, and bring them happiness,” he says.

People to relate to the messages in his songs

On the other hand, he hopes that his music can generate income, which he believes will be helpful if he wants to own a farm. He looks forward to his music bringing him a better life.

Zondi describes his music as maskanda (traditional), representing the Zulu culture. “Those interested in the culture can gain something through this music. When I compose or write a song, I ensure that people can relate to the message being delivered,” he says, adding that his songs reflect people’s lives, often his own, as well as everyday occurrences.

He features as the lead guitarist and also handles vocals and composition. Zondi is accompanied by other musicians on bass guitar, keyboard, and concertina. 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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