Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
19 April 2024 | Story André Damons | Photo Supplied
Dr Milton Mogotsi
Dr Milton Mogotsi graduated on Thursday with the degree Doctor of Philosophy with specialisation in Virology during the Faculty of Health Sciences at the University of the Free State (UFS) autumn graduation ceremonies.

A pilot study for his master’s degree not only ignited Dr Milton Mogotsi’s passion but he was also inspired by the fact that this was a newly emerging field of research in the discipline of virology at the time. This eventually led to him pursuing a PhD and ing on his research.

Dr Mogotsi graduated on Thursday (18 April) with the degree Doctor of Philosophy with specialisation in Virology during the Faculty of Health Sciences at the University of the Free State (UFS) autumn graduation ceremonies. Prof Martin Nyaga, Head of the Next Generation Sequencing Unit (UFS-NGS) and an associate professor in the Division of Virology, was his promotor and Prof Trudi O’Neill from the Department of Microbiology and Biochemistry his co-promotor.

“It feels great! It was exhausting and overwhelming at times, but that light at the end of the tunnel will start to be brighter. I feel so proud of myself and very free. Nothing beats that liberating feeling that I have successfully completed a doctoral degree and now a new chapter of my life begins. I believe this post-PhD period is an excellent time for reflecting on my attributes and revising my CV, and with a PhD degree under my belt, I look forward to an abundance of opportunities that will soon open up,” says Dr Mogotsi after graduating.

Research

According to him, he was first introduced into this research concept when he was doing his master’s degree in microbiology. “Although it was more of a pilot study aiming to assess the feasibility of conducting this type of research on a larger scale, we made some interesting findings which we published in an international journal.

“I obtained my degree with distinction, receiving an award for Best Master’s Dissertation in Microbiology. The findings of this research really ignited my passion, and I was also inspired by the fact that this was a newly emerging field of research in the discipline of virology at the time, and of course in my master’s research there were some gaps and limitations which needed to be addressed. I then took a decision to pursue a PhD and expand on that research, and working with new-born babies is always enjoyable,” says Dr Mogotsi. 

With his thesis titled “Longitudinal characterisation of the enteric virome of infants from the Free State, South Africa, using viral metagenomics”, Dr Mogotsi’s research aimed to characterise the total assemblage of all viruses that colonise the gastrointestinal tract of newborns, often referred to as the gut virome, using metagenomics.

“We know that the human gut undergoes some changes as the new-born baby becomes exposed to the numerous microorganisms, such as viruses, from the immediate environment. This once-in-a-lifetime occurrence can have life-long effects on the health and disease state of humans. Viral intestinal infections are among the leading causes of childhood hospitalisations and deaths, especially in Africa, and infants are at a greater risk of suffering severe illnesses due to their immature immune system,” he explains.

According to him, previous research had focused more on the investigating the population of bacteria present in the gut of new-borns, therefore, there’s a huge knowledge gap about viruses colonising this part of the human body. In South Africa, more attention has been on assessing the effectiveness of currently available vaccines and surveillance of specific disease-causing viruses such as rotavirus.

The research he was conducting, he continues, therefore, sought to characterise all intestinal viruses in healthy new-borns individuals, their source of origin, the changes in diversity and composition occurring over time, as well as their potential implications on the health of infants. “The findings of my study have provided more insights into what is known or new viruses are colonising the infants’ gut, as well as their evolution over time”, he adds.

PhD journey

Even though he had to put his PhD on hold for a year due to COVID-19, but with the resilience, persistence, and his ability to clear the roadblocks that were in his way, he managed to complete it. He also credits his supportive mentors and a community of colleagues and friends for their unwavering support throughout his academic journey.

“After a year-long delay, I was able to go ahead with the project and everything went well from sample collection and sample processing in the lab. The challenging part was analysing and interpreting the data as this involved advanced bioinformatics, but in the end, I was able to find solutions and make sense out of the results I got. The study was a great success with two publications in peer-reviewed international journals emanating from this study.

“Furthermore, I had an opportunity to present my research in local and international conferences. I have been to Ghana, Nigeria and Indonesia. Locally, I presented in a conference in Johannesburg and in Cape Town. More exciting was participating in the Three Minute Thesis (3MT) competition in which I emerged victorious, winning the National 3MT competition. The other award I received was from the Faculty of Health Sciences Research Forum, winning the Dr Lehlohonolo Mathengtheng Trophy for best PhD presentation”, says Dr Mogotsi.

Motivation

Dr Mogotsi says the fact that he comes from the township and received his secondary education from a township school always kept him motivated. He is well aware that there are many who look up to him, who are also inspired by what he has achieved.

“More importantly, my supervisor, Prof Nyaga, was very supportive and he is very active in his research field with genuine interest in student projects, while making time to provide adequate supervision and mentorship. His high standards of ensuring that students graduate with a strong publication record is commendable.”

As a coordinator of wet lab activities at the UFS-NGS Unit, Dr Mogotsi is currently involved in several projects as the unit is a World Health Organisation Collaborating Center for Vaccine Preventable Diseases and Pathogen Genomics. They are doing collaborative projects with several partners across the continent on the genomic surveillance of enteric viruses such as rotavirus, norovirus, sapovirus, astrovirus and adenoviruses. 

News Archive

Founding meeting of the Advisory Panel of the International Institute of Diversity
2008-11-21

The University of the Free State (UFS) today (20 November 2008) successfully convened and hosted the founding meeting of the Advisory Panel of the International Institute of Diversity.

In the wake of the Reitz video incident, the UFS wishes to establish an institute that will study and promote transformation on the campus as a microcosm of the much broader socio-political challenges facing South Africa. It is hoped that in due course the UFS and the institution will develop the expertise and experience to help other organisations and societies in transition.

The institute will work closely with the Transformation Cluster – one of six strategic academic clusters already created as part of the university’s long-term strategic plans.

Given the transformation climate in which it finds itself, the university recognises that the guidance, support and direct involvement of thought leaders and other specialists in the field of transformation are critical to the design and operation of the proposed institute. To this end, the university has established an advisory panel for the institute. The Advisory Panel will give guidance to the Executive Director (to be appointed) in helping with the conceptualisation, design, and development of the institute, and the compilation of its business plan.

Brian Gibson Issue Management facilitated the meeting and is also responsible for the reporting on the meeting. The International Institute for Development and Ethics (IIDE) co-hosted and provided the secretarial support for the meeting.

 


The members of the advisory panel:  

(Click here to read more about the Panel Members)

External panel members:

Dr Clint Le Bruyns, Senior Lecturer in Public Theology and Ethics at the University of Stellenbosch .

Dr Sebiletso Mokone-Matabane, Chief Executive Officer, Sentech Limited.

Dr Andries Odendaal works in the field of conflict transformation with international agencies such as the United Nations, DANIDA and GTZ.

Prof. Lungisile Ntsebeza, National Research Foundation (NRF) Research Chair in Land Reform and Democracy in South Africa in the Department of Sociology, University of Cape Town.

Mr Roger Crawford, Executive Director for Government Affairs and Policy South Africa, Johnson & Johnson.

Prof. Jonathan Jansen, Dean of the Faculty of Education, University of Pretoria 2001 to 2007.

Ms Zandile Mbele, Director of Plessey (PTY) Ltd. and the Transformation Executive for Dimension Data.

Dr André Keet, Director: Transdisciplinary Programme at the University of Fort Hare in October 2008 and part-time Commissioner with the Commission for Gender Equality.


Dr Reitumetse Obakeng Mabokela is an associate professor in the Higher, Adult, and Lifelong Education Program in the Department of Educational Administration at Michigan State University.

Dr Mpilo Pearl Sithole is a senior research specialist in the Democracy and Governance Research Programme at the Human Science Research Council.

Professor Steven Friedman, D.Litt. is Director of the Centre for the Study of Democracy at Rhodes University and the University of Johannesburg.

Representatives from UFS:

Prof. Teuns Verschoor, Vice-Rector: Academic Operations at the University of the Free State, and currently Acting Rector and Vice-Chancellor.

Prof. Piet Erasmus, Interim Co-ordinator for the Cluster Transformation in Highly Diverse Societies.

Prof. Lucius Botes, Director of the Centre of Development Support and Programme Director of the Postgraduate Programme in Development Studies.

Prof. Philip Nel, Former Director of the Centre for Africa Studies at the UFS.
 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept