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01 April 2024 | Story Lacea Loader | Photo Sonia Small
Prof John Klaasen, newly appointed Dean: Theology and Religion at the UFS
Prof John Klaasen, newly appointed Dean: Theology and Religion at the UFS.

The University of the Free State (UFS) has appointed Prof John Klaasen as Dean: Faculty of Theology and Religion from 1 April 2024. 

Prof Klaasen is Professor of Theology and has served two terms as Head of the Department of Religion and Theology at the University of the Western Cape. He also served as Professor in the Kjell Nordstokke Chair in Community Development at VID Specialized University in Norway and is Adjunct Professor at VID Specialized University. 

“With his vast experience and involvement in research projects – nationally as well as internationally – Prof Klaasen will make a significant contribution to the Faculty of Theology and Religion and the university in general. This will also be valuable in support of the university’s Vision 130, which is an expression of our strategic intent to position the institution towards 2034 when the UFS will be 130 years old,” says Prof Francis Petersen, Vice-Chancellor and Principal of the UFS.

As a practical theologian, the intersection between praxis and theory has occupied Prof Klaasen’s research for the past decade. He has researched and published extensively within theology, community development, and narrative. Aspects such as narrative, embedded knowledge, participation, reconciliation, and the non-rational tradition of knowledge are some of the areas that occupy his research outputs.

He is involved in numerous international research projects, which include a COST project with 17 European institutions, a project on reconciliation processes with institutions in Canada and Nordic countries, an international initiative on community development with various institutions in Europe, and a NORPART initiative with Norway and Malawi.

Community engaged scholarship forms a central part of his research and work at the intersection of religion and social justice. Prof Klaasen is involved in various community development projects, including homes for the aged, lay training, water issues, and lay theological education.

His teaching is situated within a socially just pedagogy, which puts the students at the centre of knowledge production. This innovative way of knowledge production intersects students, teachers, and the lecture room within a dynamic space of contextualisation.

“I am grateful for the opportunity to join such a prestigious institution and will endeavour to contribute to Vision 130 through commitment, innovation, trust, and ethical leadership – which represents the university’s commitment to be recognised by our peers and society as a top-tier university in South Africa, ranked among the best in the world,” says Prof Klaasen.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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