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26 April 2024 | Story Athembele Yangaphi | Photo Supplied
Dr Tafadzwa Maramura and Christopher Strydom
Dr Tafadzwa Maramura and Christopher Strydom at 2024 ASSADPAM Ceremony at the University of Pretoria's Future Africa Campus.

A trio of 2024 University of the Free State (UFS) honours-degree graduates recently represented the UFS at the 2024 Association of Southern African Schools and Departments of Public Administration and Management (ASSADPAM) Conference.

Nameera Bade, Christopher Strydom, and Thato Tshabalala’s presentation was based on their 2023 honours research titled ‘Exploring the Influence of Loadshedding on Water Governance: A Case of the Mangaung Metropolitan Municipality’, which earned them each a distinction on their honours degree completion.

The 2024 ASSADPAM Conference was held at the University of Pretoria's Future Africa Campus and brought together academics and practitioners in the field of public administration and management.

The three graduates are currently continuing their studies by taking on master’s degrees in administration – Bade and Strydom at the UFS and Tshabalala at the University of South Africa.

“Presenting our study at the ASSADPAM Conference was an absolute honour,” Strydom said. “However, I did experience some imposter syndrome, because usually it is only PhD candidates and tenured academics that present their work at the conference, [not a] first-year master’s student presenting out of his honours mini-dissertation. But I quickly got over my imposter syndrome by reframing the situation.”

The trio’s conference presentation was preceded by their recognition for Best Presentation at the UFS second Library and Information Services Honours and Undergraduate Seminar (LISHURS) Symposium on 5 April 2024.

“Being awarded the best presentation at the second LISHURS confirmed how impactful our research is, how it resonates with people. And it was also satisfying to get credit for the hard work we have put in,” said Strydom, who also received two awards at the 2024 Faculty of Economic Management Sciences (EMS) Prize Function: Best Honours Student in the Department of Public Administration and Management, and Best Honours Student in the EMS Faculty – prizes sponsored by the Kovsie Alumni Trust.

Dr Tafadzwa Maramura, Senior Lecturer in the UFS’s Department of Public Administration and Management, co-presented the research with the students at the conference. “Working with Nameera, Chris, and Thato has been a great experience. All of them are talented and unique individuals,” Dr Maramura said.

Impactful research in public governance

He highlighted the significance of the students' research, stating, “[Their paper] has certainly had a profound impact on the EMS Faculty.”

Dr Maramura further emphasised the department's commitment to addressing real-world challenges through rigorous academic inquiry, praising the students for engaging in relevant and timely research initiatives.

The collaboration between the three students and Dr Maramura extends beyond conference presentations: they are set to write an article based on their honours research for publication in a journal, which will further establish their names within the water-energy sphere and contribute to ongoing discussions in public governance.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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