Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
12 December 2024 | Story André Damons | Photo André Damons
Dr Innocensia Mangoato
Dr Innocensia Mangoato graduated on Tuesday (10 December 2024) with degree Doctor of Philosophy with specialisation in pharmacology at the Faculty of Health Sciences’ December graduation ceremony. Here she is with her supervisor and mentor Prof Motlalepula Matsabisa, Director of the University of the Free State (UFS) Department of Pharmacology.

A lecturer and researcher from the University of the Free State (UFS) Department of Pharmacology hopes her research into the use of cannabis in reversing anticancer drug resistance is a step forward into treating various cancers especially in Southern Africa.

Dr Innocensia Mangoato graduated on Tuesday (10 December 2024) with the degree Doctor of Philosophy with specialisation in pharmacology at the Faculty of Health Sciences’ December graduation ceremony. She started her career as a research scientist in the area of African traditional medicines in 2018 and her research received both national and international recognition.

“It’s an amazing (feeling to graduate today). My PhD journey was smooth and beautiful and with mentorship of Prof (Motlalepula) Matsabisa, who groomed me well, I did not shed a tear,” said Dr Mangoato. Dr Gudrun S Ulrich-Merzenich from the University of Bonn in Germany, was her co-supervisor with Prof Matsabisa.

According to the graduation programme, Dr Mangoato, Lecturer and Researcher in the UFS Department of Pharmacology, with her thesis titled Investigating the anticancer and possible resistant reversal effects of cannabis sativa l. extracts in cervical cancer cell lines and modulation of ABC transporters comprehensively explored the therapeutic potential of Cannabis sativa L. in overcoming drug resistance in cervical cancer using in vitro and network pharmacology approaches.

A step forward for treating various cancers

The research looked at the chemical fingerprints and pharmacological targets of C. sativa L. extracts, highlighting its antiproliferative properties against normal non-cancerous cells, cervical cancer cells and the cisplatin-resistant cervical cancer cells. Through PCR analysis, distinct gene expression profiles were identified, revealing the potential effects of combination treatments to counteract cisplatin resistance by downregulating genes associated with drug transporters and crucial signalling pathways. This work provides valuable insights into innovative therapeutic strategies for improving cervical cancer treatment, highlighting new avenues for overcoming resistance and enhancing treatment efficacy though the possible use of plant extracts.

“I hope my research takes a step forward in treating various cancers – especially gynaecology cancers in the Southern Hemisphere in Africa. Hopefully the research can later transcend into clinical trials and hopefully influence more policymakers. We also hope to further develop cannabis to be used as an adjuvant therapy for those drugs that are failing to treat cancer,” says Dr Mangoato, who was the recipient of the Women in Science Master’s Student in 2018.

Her graduation was also a proud moment for Prof Matsabisa, an expert in traditional African medicine, who was like a father to her during her studies. “Prof identified me from my honours degree and walked this journey with me. He has been a great mentor, a father and an amazing supervisor.”

Dr Mangoato says she will for now focus on research only and helping and monitoring upcoming researchers, especially female researchers as there is a scarcity of them her field. 

News Archive

UFS Safety Awareness March set to create a safe space for students
2017-07-27

 Description: Suspicious behavior Tags: safety, campaign, SRC, communication, awareness


The University of the Free State (UFS), in collaboration with various stakeholders, has dedicated the week of 24 to 28 July 2017 to creating awareness for the safety of students on and around its campuses.

UFS and CUT unite for safety
The highlight of the week will be on Thursday 27 July 2017 when a safety awareness march will take place from the Main Building on the Bloemfontein Campus to the Bram Fischer Building, where a memorandum will be handed over to Mr Sam Mashinini, MEC for Police, Roads, and Transport in the Free State. The march is a partnership between the UFS Student Representative Council (SRC) and the Central University of Technology (CUT).

 During a meeting on 24 July 2017, the Executive Committee of Senate granted formal approval for students and staff of the Bloemfontein Campus to take part in the safety march on 27 July 2017. For this reason, all lectures will be suspended from 11:00 to 13:00 on 27 July 2017 in order to give the campus community the opportunity to participate in the march. Academic staff, as well as staff in the administrative support services, are encouraged to join the march.

Programme for the safety march:


11:00: Marchers gather in front of the Main Building

11:15: Marchers depart from the Main Building to the Main Gate

11:30: Marchers exit the Main Gate and move towards the Central University of Technology (CUT). Students and staff who are unable to participate in the rest of the march, return to their work places or classes.

12:20: UFS and CUT marchers will gather at the Bram Fischer Building, situated on the corner of Nelson Mandela Avenue and Markgraaff Street. Here, the Rector and Vice-Chancellor of the UFS, Prof Francis Petersen, and the Vice-Chancellor and Principal of CUT, Prof Henk de Jager, will address the marchers, after which the memorandum will be read by the respective SRC Presidents and handed to Mr Mashinini.

Activities underway to raise safety awareness
During the week, the Student Representative Council (SRC), together with other stakeholders, have been involved in several activities on and off the Bloemfontein Campus, including door-to-door visits to student homes and residences on and around campus, awareness campaigns at all the gates of the campus, and a Safety Dialogue that will be held on Wednesday 26 July 2017 at the Equitas Auditorium. The aim of the Safety Week is to focus on informing, educating, and encouraging students as well as the Mangaung community at large, in order to work together in creating a safe environment for students.

The week started with the roll-out of an awareness campaign titled Reach Out, which is set to bring students and the community of Mangaung together to help decrease the number of violent crimes faced by students off campus. The communication plan includes safety messages, using outdoor billboards, posters on lampposts around the residential student areas, local community radio stations, campus media, and the university’s social media platforms.

A similar student safety awareness campaign will take place on the university’s Qwaqwa Campus during the week of 31 July 2017.



We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept