Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
12 December 2024 | Story André Damons | Photo André Damons
Dr Innocensia Mangoato
Dr Innocensia Mangoato graduated on Tuesday (10 December 2024) with degree Doctor of Philosophy with specialisation in pharmacology at the Faculty of Health Sciences’ December graduation ceremony. Here she is with her supervisor and mentor Prof Motlalepula Matsabisa, Director of the University of the Free State (UFS) Department of Pharmacology.

A lecturer and researcher from the University of the Free State (UFS) Department of Pharmacology hopes her research into the use of cannabis in reversing anticancer drug resistance is a step forward into treating various cancers especially in Southern Africa.

Dr Innocensia Mangoato graduated on Tuesday (10 December 2024) with the degree Doctor of Philosophy with specialisation in pharmacology at the Faculty of Health Sciences’ December graduation ceremony. She started her career as a research scientist in the area of African traditional medicines in 2018 and her research received both national and international recognition.

“It’s an amazing (feeling to graduate today). My PhD journey was smooth and beautiful and with mentorship of Prof (Motlalepula) Matsabisa, who groomed me well, I did not shed a tear,” said Dr Mangoato. Dr Gudrun S Ulrich-Merzenich from the University of Bonn in Germany, was her co-supervisor with Prof Matsabisa.

According to the graduation programme, Dr Mangoato, Lecturer and Researcher in the UFS Department of Pharmacology, with her thesis titled Investigating the anticancer and possible resistant reversal effects of cannabis sativa l. extracts in cervical cancer cell lines and modulation of ABC transporters comprehensively explored the therapeutic potential of Cannabis sativa L. in overcoming drug resistance in cervical cancer using in vitro and network pharmacology approaches.

A step forward for treating various cancers

The research looked at the chemical fingerprints and pharmacological targets of C. sativa L. extracts, highlighting its antiproliferative properties against normal non-cancerous cells, cervical cancer cells and the cisplatin-resistant cervical cancer cells. Through PCR analysis, distinct gene expression profiles were identified, revealing the potential effects of combination treatments to counteract cisplatin resistance by downregulating genes associated with drug transporters and crucial signalling pathways. This work provides valuable insights into innovative therapeutic strategies for improving cervical cancer treatment, highlighting new avenues for overcoming resistance and enhancing treatment efficacy though the possible use of plant extracts.

“I hope my research takes a step forward in treating various cancers – especially gynaecology cancers in the Southern Hemisphere in Africa. Hopefully the research can later transcend into clinical trials and hopefully influence more policymakers. We also hope to further develop cannabis to be used as an adjuvant therapy for those drugs that are failing to treat cancer,” says Dr Mangoato, who was the recipient of the Women in Science Master’s Student in 2018.

Her graduation was also a proud moment for Prof Matsabisa, an expert in traditional African medicine, who was like a father to her during her studies. “Prof identified me from my honours degree and walked this journey with me. He has been a great mentor, a father and an amazing supervisor.”

Dr Mangoato says she will for now focus on research only and helping and monitoring upcoming researchers, especially female researchers as there is a scarcity of them her field. 

News Archive

Future Leader’s Award 2017 goes to UFS Quantity Surveying student
2017-08-11

Description: Future Leader’s Award 2017 goes to UFS Quantity Surveying student Tags: Future Leader’s Award 2017 goes to UFS Quantity Surveying student 

Celebrating big achievements in the construction
sector at the recent Association of South African
Quantity Surveyors (ASAQS) conference are, from
the left: Cameron Ferreira, junior lecturer in the
UFS Department of Quantity Surveying,
Jhon Thatcher, former UFS student in the same
department who was the second runner-up for the
Gold Medal Award, Dr Stephan Ramabodu, President
of ASAQS, Gerné Bothma, former student in the
department and winner of the Future Leaders’
Award 2017, and Pierre Oosthuizen, UFS lecturer in
the same department.
Photos: Supplied


The Department of Quantity Surveying and Construction Management at the University of the Free State (UFS) made good on its promise to develop independent and critical-thinking graduates who will become leaders in their field. At the recent Association of South African Quantity Surveyors (ASAQS) conference and gala dinner, two students from the department, Gerné Botma and Jhon Thatcher, received awards for their outstanding performance.

Best of the best
Botma received the ASAQS Future Leaders’ Award (2017), an award based on academic achievement in the first three years of study. He competed with nominees from universities across South Africa offering Quantity Surveying programmes, and was the winner in this category.

Thatcher was a second runner-up for the ASAQS Gold Medal Award (being in the top three Quantity Surveying students in South Africa). This is awarded on a number of criteria, including academic achievement. Fourth-year students from all the universities in South Africa offering Quantity Surveying programmes compete for this award, and must display achievement in categories such as academia, leadership, community engagement, and general interests.  In 2016, the Gold Medal Award was won by the UFS student, Kamogelo Leeuw.

Keeping abreast of developments
Today, organisations are relying on its members to stay ahead of issues, technologies, innovations and trends. In Quantity Surveying, to keep abreast of developments in the built environment, ASAQS was established as a voluntary association, with one of its goals being advancing and promoting the science and practice of Quantity Surveying.  ASAQS works in close collaboration with its member firms, tertiary institutions, and the South African Council for Quantity Surveying Professions (SACQSP), a statutory body that oversees and regulates the profession, and accredit Quantity Surveying programmes in South Africa.

Two staff members from the UFS Department of Quantity Surveying and Construction Management, Cameron Ferreira and Pierre Oosthuizen, attended the recent ASAQS annual conference. Ferreira, a junior lecturer in the department, is the current Chapter Chairperson of the Free State for ASAQS and Oosthuizen, a lecturer in the department, is the former Chapter Chairperson.

According to Ferreira, they attended the conference to keep abreast of the latest development within the industry. “The event also served as a great networking opportunity for the UFS to build partnerships with other industry pioneers,” she said. Making use of opportunities such as these is in line with the UFS’s pursuit of lifelong learning.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept