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29 February 2024 | Story Leonie Bolleurs | Photo SUPPLIED
Dr Lindie von Maltitz
Dr Lindie von Maltitz spoke at DESTEA’s Free State Investment Conference (27 February), which was hosted on the UFS Bloemfontein Campus. In her presentation, she highlighted, among other points, the advantages of the UFS as a strategic partner in the agricultural sector.

Dr Lindie von Maltitz, a Lecturer in the Department of Agricultural Economics at the University of the Free State (UFS), contributed to the programme of the Free State Investment Conference (27 February), which was presented by the Department of Economic, Small Business Development, Tourism, and Environmental Affairs (DESTEA).

The primary objective of the conference, held in the Centenary Complex on the UFS Bloemfontein Campus, was to promote the province as an investment destination of choice and to showcase strategic investment projects across different municipalities. Additionally, the conference sought to connect local businesses with local and international investors and opportunities.

Representatives from financial institutions, academic institutions, national and provincial government departments, chambers of commerce, corporates, investors, and embassies attended the conference, which was opened by Councillor Gregory Nthatisi, the Executive Mayor of the Mangaung Metropolitan Municipality. The honourable Mxolisi Dukwana, the Premier of the Free State, delivered the keynote address.

The sectors covered by the presentations at this conference included mining and gas extraction, transport and logistics, energy, infrastructure, tourism, and the agriculture and agro-processing sector. Dr Von Maltitz’s presentation, ‘Required investment to improve the performance of the agricultural sector in the Free State’, focused on the latter sector.

Representing the UFS in the session ‘Driving Inclusive Growth and Food Security: Agriculture’ – Dr Von Maltitz first focused on what agriculture in the Free State entails, and how it relates to the rest of the country. She then provided a brief overview of the role and importance of agriculture in the South African and Free State economy, adding to that the advantages that investment in the agricultural sector in the Free State will bring.

Numerous possibilities for investment in the sector

According to Dr Von Maltitz, the agricultural sector in the Free State is of vital importance to its economy. “Our income from agriculture and its related industries is the second largest in the country, after the Western Cape. There are numerous possibilities for investment in the sector, not limited to production, but expanded to the entire agricultural value chain. Connecting with the right strategic partners can ensure the success of investment projects. The UFS can contribute as a strategic partner, bringing knowledge, expertise, research, and local and global networking to the table,” she stated.

The importance of investing in the agricultural sector, according to Dr Von Maltitz, is linked to two of South Africa’s biggest challenges: unemployment and poverty. “Investing in agriculture addresses both of these issues. Jobs are created for both unskilled and skilled labour while producing and processing food. The higher agricultural investment is on the agenda, the better for economic growth in our province and country,” said Dr Von Maltitz.

"With food security for a global population that has expanded from 2,5 billion in 1950 to 7,9 billion in 2021, agriculture and its related industries are the sector that will remain important until time immemorial,” remarked Dr Von Maltitz.

She is of the opinion that the Free State presents many opportunities for this sector. Dr Von Maltitz believes there are very few agricultural products that cannot be produced in the Free State. “For example, fruit produced in our province is market-ready before that of the Western Cape. This allows us to access local and international markets early, when prices are higher due to a supply shortage. Because we have cold temperatures in winter, our area has fewer livestock diseases than those found in other parts of the country,” she added.

“Assured by a supportive policy environment, functional infrastructure, and expert knowledge base, investors can be encouraged to invest in the agricultural sector in the Free State,” said Dr Von Maltitz.

In the Free State, however, the development of the agricultural sector is facing several challenges. In her view, failing infrastructure and load shedding are the biggest problems. “Our roads are among the worst in the country, making timely access to markets more difficult. Load shedding has an enormous impact on any processing facility. Climate change is something we need to incorporate into our planning process, continuously developing new risk management strategies for the sector,” she elaborated.

Advantages of the UFS as a strategic partner

She stated that the Free State is an agricultural hub open to many more possibilities. “Speaking as a representative of the UFS, I want to highlight the advantages for investors of the UFS as a strategic partner. Our Faculty of Natural and Agricultural Sciences is one of the best in the country and offers knowledge, skills, and expertise in every field related to agriculture, including soil scientists, animal scientists, climate scientists, crop scientists, wildlife and grassland scientists, plant breeders and pathologists, agronomists, agrometeorologists, and agricultural economists. The value we offer can be attractive to investors who will be reassured by our competence, as supported in the university’s Vision130, which defines our values, namely excellence, innovation and impact, accountability, care, social justice, and sustainability,” Dr Von Maltitz said.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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