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01 March 2024 Photo Unsplash
Africa
Collaborating across continents, the Centre for Gender and Africa Studies at the University of the Free State (UFS), alongside the Centre for African Studies at Jawaharlal Nehru University (JNU) in India and the African Studies Association of India (ASA India), held a pivotal international webinar titled 'Africa’s Global Engagements: Opportunities and Challenges,' on 27 and 28 January 2024.

In the midst of a global landscape marked by rapid changes, Africa finds itself at the epicentre of a new wave of international interest. This intrigue stems from a myriad of factors, ranging from the continent’s abundant natural resources to its strategic geopolitical positioning. However, amidst this renewed attention, questions arise regarding Africa’s agency and its place in the evolving global order.

In recent times, there has been a notable surge in global actors vying for influence in Africa. From former colonial powers to emerging economies like China and India, various stakeholders seek to engage African nations on multiple fronts, spanning from economic cooperation to security collaborations. Against this backdrop, it becomes imperative to delve into Africa’s international engagements to grasp the nuances of its evolving role on the global stage.

Addressing this imperative, the Centre for Gender and Africa Studies at the University of the Free State (UFS), in collaboration with the Centre for African Studies at Jawaharlal Nehru University (JNU) in India and the African Studies Association of India (ASA India), convened an international webinar titled, Africa’s Global Engagements: Opportunities and Challenges. Held on 27 and 28 February 2024, the event was jointly opened by Prof Vasu Reddy, Deputy Vice-Chancellor of Research and Internationalisation at the UFS and Prof Ajay Dubey, former Pro Vice-Chancellor at JNU and currently a professor in the Centre for Africa Studies at JNU. The conference brought together scholars and policymakers from diverse backgrounds and regions, united in their quest to comprehensively understand Africa’s evolving position in the global arena.

In his opening remarks, Prof Vasu Reddy, underscored the timeliness of the conference aligning it to the institution’s visionary framework, Vision 130. He highlighted the centering of Africa as a focal point for addressing broader global challenges emphasising the interconnectedness of Africa’s experiences with broader global narratives. Prof Reddy articulated how Africa serves as a nexus for transnational interactions, intertwining diverse histories, politics, and socio-economic dynamics with the larger global discourse.

Moreover, the conference shed light on the concept of the “Global South” and its implications in the contemporary global order. Participants deliberated on the complexities of African agency within this framework, examining how African states navigate their engagements with a myriad of international actors while asserting their own interests and priorities.

The event not only symbolised a collaboration between the UFS and JNU, as outlined in their Memorandum of Understanding (MoU), but also signified a shared commitment towards prioritising engagements within the Global South. Through platforms like these, institutions like UFS and JNU demonstrate their dedication to fostering meaningful dialogues and scholarly exchanges that transcend geographical borders.

As Africa continues to navigate its place in the fast-changing global landscape, initiatives such as this webinar serve as critical platforms for fostering mutual understanding and cooperation among scholars and policymakers worldwide. By engaging in nuanced discussions and collaborative efforts, stakeholders can collectively contribute to shaping a more inclusive and equitable global order.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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