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Dr Grey Magaiza: passionate about empowering communities

12 January 2024 | Story Nonsindiswe Qwabe | Photo Sonia Small

Dr Grey Magaiza read more — Since joining the UFS in 2008, Dr Grey Magaiza has worked extensively on approaches that can foster the socio-economic transformation of societies.

“The future should be one where communities can decide on their development agenda and futures. That’s the most important for me.” Dr Grey Magaiza, Deputy Director of the Centre for Gender and Africa Studies (CGAS) and Head of the Community Development programme on the Qwaqwa Campus, is passionate about capacitating communities to be agents of change and advancement. His vision for the future emphasises the empowerment of communities to take charge of their development by actively participating in decision making and the implementation of development projects that can improve their lives.

Since joining the UFS in 2008, Dr Magaiza has worked extensively on approaches that can foster the socio-economic transformation of societies. Over the years, he has crafted his research speciality into one that he is most proud of – being an interdisciplinary scientist immersed in the development of communities.

Social entrepreneurship

“I’m in a fortunate position of researching what I like. I say ‘fortunate’, because I’ve taken the time to understand what I’m passionate about, which is the overall field of rural livelihoods and livelihood futures – in short, community development. My research starts from an engaged university, understanding the elements that a university must use to enhance transformation and relevance to its immediate community in terms of development.”

One of the ways he has done this is by looking at social entrepreneurship as a development approach for young people in a rural setting. Through workshops with non-profit and civic organisations in Qwaqwa, Dr Magaiza has been helping these organisations to map out their needs and actively meet them through the involvement and support of external role players.

Community organising

“We understand that communities are part of the national development agenda, but even that national agenda respects community knowledge and intentions and allows communities to shape their identity. A critical enabler of this is community organising. You bring back the capacity in communities to have dialogues on issues affecting them as spaces for engagement, knowledge exchange, and for people to just talk about their way forward.”

By enabling communities to define their development agenda, they can address their specific needs, challenges, and aspirations, he said. “When I look at livelihood futures, it’s quite an exciting aspect of my work – it’s like looking into a fortune tellers’ globe, because you’re not deciding for communities what they should do, but the communities themselves take those decisions.”

News Archive

Nuclear Medicine on the forefront of cancer research

2017-07-10

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma. The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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