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25 January 2024
EASA conference

The University of the Free State’s Bloemfontein campus played host to the English Academy of Southern Africa’s (EASA) annual international conference on 7-8 December 2023.  Attracting 35 delegates from Canada, the UK, Nigeria, Botswana, and South Africa, the two-day conference delved into the theme, “Ways of Reading: Literature and Literacy,” with a diverse group seeking to unravel the intricate relationship between literature and literacy.

The proceedings were inaugurated by Prof Vasu Reddy, emphasising the importance of exploring how literacy shapes our modes of attention, both culturally and socially. He expressed his faith that the conference would be “generatively disruptive,” noting that “where there is disruption, there is also growth.”

Featuring two eminent keynote speakers, the conference saw Prof David Attwell, Emeritus Professor at the University of York (UK), discussing the connection between translingualism and creativity in a lecture titled, “A Ventriloquial Literature: The Art of ‘Throwing the Voice’ in the South African Canon. On the second day, Dr Karen Jennings, author of the Booker Prize longlisted novel An Island, reflected on “how place and identity are crucial to the act of creation,” with her talk whimsically titled, “Bums in the Ground.”

Delegates approached the conference theme in various ways, with some exploring how specific writers or critical movements have shaped scholarly reading habits. Others highlighted the significance of literacy for social justice. This diversity extended to the interdisciplinary nature of the conference, bringing together scholars working in language practice, literary studies and even the medical humanities.

Convened by Dr Rick de Villiers, a senior lecturer in the Department of English and the regional vice-president of EASA, the conference delighted in attracting scholars from different backgrounds and stages of their careers. “We had a wonderful mix of established and early-career scholars. The atmosphere was rigorous and robust but collegial throughout.”

Speaking on behalf of EASA, Dr De Villiers extended gratitude for the financial and administrative support from the UFS, particularly the Department of English.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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