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25 January 2024 | Story Leonie Bolleurs | Photo Sonia Small
Prof Corinna Walsh
Prof Corinna Walsh says the PEA POD Infant Body Composition System works by directly measuring an infant’s body weight and volume, and then uses these measurements to calculate the body fat percentage, fat mass, and fat-free mass.

Nutritional and growth patterns during early life have been associated with health, development, and well-being throughout the life cycle. It is also associated with risks for developing obesity and non-communicable diseases, such as cardiometabolic diseases, later in life. These are the findings of Prof Corinna Walsh, Professor in the Department of Nutrition and Dietetics.

Maternal and child health

”In line with national priorities, a strong research focus area of the Faculty of Health Sciences and the School of Health and Rehabilitation Sciences is maternal and child health,” she says. She goes on to mention that the Department of Nutrition and Dietetics has established a reputable research programme. This programme focuses primarily on the nutritional status of pregnant women and how the early environment to which they are exposed during and after pregnancy affects short- and long-term health outcomes of the offspring.

“In our previous work, the assessment of birth outcomes of infants was, however, limited by the lack of equipment to analyse body composition. The research that we can conduct with the PEA POD® provides us with immense additional potential,” remarks Prof Walsh.

She explains, “The PEA POD Infant Body Composition System is an infant-sized air displacement plethysmography system. It works by directly measuring an infant’s body weight and volume, and then uses these measurements to calculate the body fat percentage, fat mass, and fat-free mass.

According to her, the assessment of body volume takes two minutes. “The PEA POD technique also does not require collection of any fluids and does not expose the infant to radiation. It can be performed as often as required without any risks and be used up to a maximum of 8-10 kg body weight, from birth to about eight months,” she says.

Advanced technology

In the context of research on infant body weight and composition, there is a need for accurate measurement techniques that can differentiate between fat mass and fat-free mass. Prof Walsh is of the opinion that traditional measures such as body mass index (BMI) and weight for length have limitations in this regard, as they do not provide a clear distinction between these components. Furthermore, BMI may not be reliable for assessing adiposity or obesity in paediatric populations, and it can vary significantly with age and gender.

Addressing these challenges, the PEA POD equipment offers advanced technology that allows for highly accurate quantification of infant body composition. This technological capability opens up opportunities to study the effects of early-life nutrition on growth and the developmental mechanisms that may lead to later comorbidities. So, when it comes to researching infant body weight and composition, the PEA POD equipment plays a crucial role in providing precise data and insights.

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Prestige Scholar hosts Prof John Helliwell of Manchester University
2015-12-08

From left is Prof John R. Helliwell (School of Chemistry, University of Manchester), Dr Madeleine Helliwell (School of Chemistry, University of Manchester), Prof Andre Roodt (Department of Chemistry, University of the Free State) and Dr Alice Brink (Department of Chemistry, University of the Free State).
Photo: Steven Collett

At the invitation of Dr Alice Brink of the Department of Chemistry, Prof John Helliwell, the 2015 Max Perutz Prize winner, and his wife, Dr Madeleine Helliwell, visited the University of the Free State (UFS).
The Helliwells, both chemists of note, took part in a series of lectures and exchanges on the Bloemfontein and Qwaqwa Campuses.
This visit from 9-19 November 2015 was the consequence of Dr Brink’s participation in the Vice-Chancellor’s Prestige Scholars Programme (PSP) initiative to encourage the broadening of the international footprint of the next generation of scholars in the academy.

Two year collaboration

Dr Brink and Prof Helliwell from Manchester University have a standing collaboration going back two years. Dr Brink, an NRF Thuthuka grant holder and a member of the PSP since 2013, has spent almost eight months in Manchester, collaborating with Prof Helliwell on her study of the successful interaction of rhenium tricarbonyl complexes with proteins determined via protein crystallography.
Their collaboration resulted from the close association of Prof Helliwell and Prof Andre Roodt from the UFS Department of Chemistry, both former presidents of the European Crystallographic Association.

Sharing academic expertise

Prof Helliwell, the 2014 American Crystallographic Association Patterson Award winner for his “pioneering contributions to the global development of the instrumentation, methods and applications of synchrotron radiation in macromolecular crystallography”, gave three lectures in the Department of Chemistry, two on the Boemfontein Campus, and the other on the Qwaqwa Campus on 13 November 2015.

Dr Helliwell, former co-editor of the Acta Crystallographica Section C: Crystal Structure Communications journal, consulted with postgraduate students from the Departments of Chemistry and Biochemistry.

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