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16 January 2024 | Story Leonie Bolleurs
Scie-Ed building

The university is transforming its campus with state-of-the-art infrastructure development. We are creating spaces that foster learning, empower groundbreaking research, and offer an enriching university experience.

UFS Sasol Library

The UFS has been hard at work to move away from traditional library spaces towards creating tech-enhanced, flexible environments that are dynamic for teaching and learning. According to Jeannet Molopyane, Director of Library and Information Services, they strive to align their spaces with global best practices with the infrastructure changes.

Centre for Mineral Biogeochemistry

The Centre for Mineral Biogeochemistry – completed in February 2023 – integrates seamlessly with its surrounding environment, while also providing a new collaborative workspace for the centre’s personnel. This state-of-the-art facility boasts various laboratories which were mainly funded by the Department of Science and Innovation (DSI). The CMBG includes, among other initiatives, the Mineral Node of the Biogeochemistry Research Infrastructure Platform (BIOGRIP), an initiative of the DSI. This space is situated next to the existing Microbiology Building on the Bloemfontein Campus. 

University Estates Building

For this repair and renovation project, with a construction theme, internal and external materials were selected for their low-maintenance qualities. The first office, located opposite the entrance door, features cladding with exposed galvanised corrugated iron. A new steel mezzanine level was installed and painted in ‘CAT’ yellow and black. All pipes, including plumbing and electrical, are exposed on wall surfaces. The use of internal exposed brickwork, concrete floors, and oriented strand board in ceilings and cupboards further accents this quality in the completed project. 

Animal Research Centre

The Animal Research Centre on the Qwaqwa Campus, replaced the temporary structure that previously served as animal housing. The new structure complies with the requirements and standards for a research facility and caters to the needs of researchers and animals, including small and large rodents. The exterior materials used complement those of the surrounding buildings, providing a low-maintenance profile. The building, accessible to persons with disabilities, contains two research laboratories, an ecotoxicology laboratory, a veterinarian’s office, and a procedure room.

South Campus 24/7 Study Space

The shift to extended programmes and dramatic increase in student enrolment on the South Campus created the need for additional study areas. Considering the steep site outcrop and the existing pedestrian routes from the lower campus, the design explored building blocks that progressively staggered up the hill to accommodate a small amphitheatre study area, maximising seating capacity. This allows the building to accommodate the site’s steepness rather than ignore it. The final design provides study spaces on three levels, all accessible via a ramp, with the main functions situated on the primary level. This design also ensures accessibility for all users, including those with disabilities.

KovsieGear

Incline Architects has designed a new innovative space on the Thakaneng Bridge on the Bloemfontein Campus to accommodate the expansion of the KovsieGear outlet. This new design incorporates extra retail space along with additional room for administration work. The KovsieGear shop now features a new aesthetic, created with natural materials to complement the UFS colours.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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