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19 June 2024 | Story André Damons | Photo Suplied
Quality of Life and Wellbeing Book Launch 2024
Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation (second from the left), was the lead editor with Profs Narnia Bohler-Muller and Prof Zitha Mokomane (left). With them is Dr Derek Davids (right), research director in the HSRC's Developmental, Capable and Ethical State research division and an advisory member at the Department of Applied Legal Studies at Cape Peninsula University of Technology.

The Human Sciences Research Council Press (HSRC Press) launched its latest book in the flagship publication State of the Nation series, titled Quality of Life and Wellbeing at the University of the Free State (UFS).

The launch took place on Thursday, 13 June in the Equitas Auditorium on the Bloemfontein Campus. Prof Vasu Reddy, Deputy Vice-Chancellor: Research and Internationalisation of the UFS, was the lead editor, with Profs Narnia Bohler-Muller, divisional executive in the HSRC’s Developmental, Capable and Ethical State research division; and acting Group Executive; Zitha Mokomane, a professor in the Department of Sociology at the University of Pretoria; and Prof Crain Soudien, Chief Executive Officer of the HSRC. Prof Soudien was not at the launch.

The discussion was facilitated by Dr Molapo Qhobela, Deputy Vice-Chancellor: Institutional Change, Strategic Partnerships and Societal Impact.

Celebrating its 20th year of existence, the State of the Nation volume, one of the HSRC’s flagship publications, serves as an invaluable, independent scholarly resource offering insights into the current state of South Africa. The 2024 edition explores themes such as the environment, quality of life and wellbeing, an open economy, mental health, the arts, human security, gender and wellbeing, vaccinations, wellbeing and happiness, and inequality in South Africa.

The state in which the nation finds itself 

In his welcome remarks, the Vice-Chancellor and Principal, Prof Francis Petersen, said two decades ago when the State of the Nation series began, South Africa was attempting to come to terms with the complex legacies of colonialism and apartheid and was contending with the post-apartheid reconstruction, development and reconciliation.

“I think there was a sense of optimism during that time for the future and a collective sense that the country’s challenges, however deep and multifaceted, those challenges were and are, could be overcome in time.

“Two decades later South Africa finds itself at a political watershed and having to deal with many of the same challenges as from 2004, such as economic inequality, social justice and effective government,” said Prof Petersen.

According to him, it is welcome to note that this volume brings to the fore new, fresh and relevant directions that address issues relating to quality of life and notions of wellbeing. Key questions that are inferred and that underpin much of the scholarship on offer, said Prof Petersen, is what is the state? Where is the state? Where does the state begin and where does it end?

“The editors offer compelling analyses that it is in the complex act of making lives of individuals acting in their own interest and the government articulating an agenda for the nation that we are able to discern the outlines of the state in which the nation finds itself.”

The scope and drivers

Prof Reddy, in his short introductory remarks, provided descriptive comments and focused on the background, the concept, the process, and some of the scope and drivers informing the text and context shaping the volume.

The latest book which took two-and-half years to produce, has two predecessor volumes published in the 2019 and 2021 respectively, with poverty and inequality and an ethics of care being a strong thematic.

“What is the importance of the scope of the volume and what makes the book unique. With this volume, thematising quality of life and wellbeing, we have seen some very interesting work being developed in the country. This particular volume is the first fully dedicated edition in the State of the Nation series dealing with this issue. We felt it was timely, we felt that this issue of Quality of Life and Wellbeing that were kind of completely interrelated,” said Prof Reddy.

According to him, some of the drivers that shaped this volume included the spectre of poverty and inequality which is an underlying implicit theme. Their implication for human wellbeing and human conditions in several different ways remains key.

Prof Reddy said the book is divided into four parts that deal with quality of life, politics and the state; economics; society, culture, identity and the public good; and looking at South Africa and beyond, including issues such as human security, gender and peace.

“The big issue with the volume’s theorical and conceptual framework is about building theory as well as much as it is also about dealing with the empirical and material realities facing citizens. The volume is predicated on quality of life and wellbeing, asking whether standards of living and styles of living lead us to a good life. And the questions we pose include: What is a good life? What are the attributes and elements of such a life? What are the conditions that need to be met to meaningfully improve quality of life and wellbeing?”

Environmental wellbeing

Talking about her chapter which addresses environmental and human health, Prof Narnia Bohler-Muller stated that the constitution was the starting point as what is embedded in the constitution is the recognition of the importance of wellbeing although the word is seldom used in the constitution.

“The first time ‘wellbeing’ is used is in Section 24 which deals with environmental rights. We thought this is a complex intersection – law, human rights, constitutionalism, health and wellbeing, and quality of life, so let’s explore it.

“We all know that the environment is extremely important. We cannot live without it. We are in a massive crisis in the world when it comes to the environment and climate change. There is an intersectionality between environment, climate, health, and wellbeing. Other issues also include clean water and the risk of extreme weather events as a result of climate change.”

Dissatisfied by the status quo in Soutth Africa

Prof Mokomane said two questions drove her co-authored chapter titled Quality of Life and political support in SA – resilient nation. The first question is: Do peoples’ perception of quality of governance influence their quality of life? And the second question was: Which aspects of government quality signify as important contributors to quality of life?

“This chapter reaffirms the notion that was held by many that the general public has become increasing dissatisfied by the status quo in South Africa over the past decade. We concluded that the political and economic crises of the past decade have perhaps begun to create a scenario in which personal fear is gaining traction over the hope that South Africans are known for.

“The overall conclusion is that for many South Africans resilience has been displaced by resignation which has introduced the risk of further disability and fragility in the country in the future.”

Profs Hussein Solomon from the Centre for Gender and African Studies and Philippe Burger, Dean of the Faculty of Economic and Management Sciences, were respondents to the text. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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