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18 June 2024 | Story André Damons | Photo Suplied
SADoCoL
Betsie Human and Elandré Williams, analysts at the South African Doping Control Laboratory (SADoCoL) at the University of the Free State (UFS), will be involved in sample preparation, analysis and data processing at the upcoming Olympic and Paralympic Games in Paris, France.

Two staff members from the South African Doping Control Laboratory (SADoCoL) which is housed at the University of the Free State (UFS), have been selected to work at the upcoming Olympic and Paralympic Games, in Paris, France.

Elandré Williams and Betsie Human will support the Paris laboratory during both games. The Olympic Games will take place from 26 July to 11 August 2024 and the Paralympic Games from 28 August to 8 September 2024.

Williams will be involved in steroid profile analysis, which includes sample preparation, analysis and data processing by Gas Chromatography (GC) and Isotope Ratio Mass Spectrometry (GC-C-IRMS).

Part of the fight against doping 

“I am excited, optimistic and privileged to have been given this opportunity, but I have to say that I am also quite nervous as this is most probably the biggest sporting event of the year. Being a part of the fight against doping in sport remains a great responsibility as what we do directly impacts the athletes,” says Williams.

She says is looking forward to the entire experience, from doing what she loves on an international level, meeting other analysts in the field and being part of the fight against doping in sport on an Olympic level.

This is her first big international sporting event.

“I am also looking forward to learning from other experts in the field who have more experience and to witness the procedures and the manner in which the laboratory operates at this time where the sample numbers are extremely high with the added pressure to finalise results in short turn-around times. This is a great opportunity for growth, both individually and in my field of expertise, in the scientific and the doping control field.

“It will definitely be an advantage for me as an analyst to get exposure to how the entire analytical procedure is executed in another laboratory, as well as insight into possible new techniques and advancements that I will be able to apply back at SADoCoL. I also think this is a great way to improve my ideas, perspectives and level of expertise as I will be working and witnessing other scientific experts in the doping control field.”

Managing workflow and logistics at the Games

Human, who was an analyst at the 2010 Soccer World Cup in South Africa, says she is both nervous and excited for this experience. 

“I was a junior analyst at SADoCoL during the 2010 Soccer World Cup, but you cannot compare a single-sport discipline with a multisport discipline like the Olympic Games – The Games will be exponentially bigger.

“In the past 14 years doping control as a whole has grown significantly. New technologies, updated requirements, more sensitive testing methods have emerged – this will be a new experience,” says Human.

She will also be involved with sample preparation/analysis/data processing and says she is looking forward to seeing how the work-flow and logistics associated with the Games (massive amounts of samples/tight deadlines etc) is managed in a high through-put laboratory.

“I am of course also looking forward to meeting analysts from other labs – we are a bit secluded here at the southern tip of Africa. Collaboration between labs is tricky when your closest neighbour is in Europe.

“It is always eye-opening to see how other labs manage similar situations (even though an Olympics is quite different from normal routine days) – exposure to new techniques and alternative thinking has a way of elevating your own thought processes and it promotes growth – both as an individual and as a doping control analyst.”

Immensely proud

Hanno du Preez, Director of SADoCoL, says the laboratory personnel are immensely proud that two of their staff members were chosen to participate in this international event, which for many scientists is the peak of their career. Similarly, this provides acknowledgement to the staff members for the area in which they have been working.

“It is only a select few who are requested to provide service at the Olympic Games. The work conducted in an Olympic laboratory provides experience which cannot be gained elsewhere. The workload and fast-paced analysis is something which the personnel are used to, but the Olympics will bring a different dimension to the processes. 

“We are excited to see what Betsie and Elandré bring back, with regards to new viewpoints on processes which are similar in all anti-doping laboratories. Individual experiences uplift everyone in a regulated business unit such as SADoCoL and also ensures improved relationships between laboratories, as other anti-doping laboratories will be represented at the Games as well. We wish them all the best for the experience, and we thank them for being dedicated ambassadors for SADoCoL and the UFS.”

News Archive

Mathematical methods used to detect and classify breast cancer masses
2016-08-10

Description: Breast lesions Tags: Breast lesions

Examples of Acho’s breast mass
segmentation identification

Breast cancer is the leading cause of female mortality in developing countries. According to the World Health Organization (WHO), the low survival rates in developing countries are mainly due to the lack of early detection and adequate diagnosis programs.

Seeing the picture more clearly

Susan Acho from the University of the Free State’s Department of Medical Physics, breast cancer research focuses on using mathematical methods to delineate and classify breast masses. Advancements in medical research have led to remarkable progress in breast cancer detection, however, according to Acho, the methods of diagnosis currently available commercially, lack a detailed finesse in accurately identifying the boundaries of breast mass lesions.

Inspiration drawn from pioneer

Drawing inspiration from the Mammography Computer Aided Diagnosis Development and Implementation (CAADI) project, which was the brainchild Prof William Rae, Head of the department of Medical Physics, Acho’s MMedSc thesis titled ‘Segmentation and Quantitative Characterisation of Breast Masses Imaged using Digital Mammography’ investigates classical segmentation algorithms, texture features and classification of breast masses in mammography. It is a rare research topic in South Africa.

 Characterisation of breast masses, involves delineating and analysing the breast mass region on a mammogram in order to determine its shape, margin and texture composition. Computer-aided diagnosis (CAD) program detects the outline of the mass lesion, and uses this information together with its texture features to determine the clinical traits of the mass. CAD programs mark suspicious areas for second look or areas on a mammogram that the radiologist might have overlooked. It can act as an independent double reader of a mammogram in institutions where there is a shortage of trained mammogram readers. 

Light at the end of the tunnel

Breast cancer is one of the most common malignancies among females in South Africa. “The challenge is being able to apply these mathematical methods in the medical field to help find solutions to specific medical problems, and that’s what I hope my research will do,” she says.

By using mathematics, physics and digital imaging to understand breast masses on mammograms, her research bridges the gap between these fields to provide algorithms which are applicable in medical image interpretation.

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