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18 June 2024 | Story André Damons | Photo Suplied
SADoCoL
Betsie Human and Elandré Williams, analysts at the South African Doping Control Laboratory (SADoCoL) at the University of the Free State (UFS), will be involved in sample preparation, analysis and data processing at the upcoming Olympic and Paralympic Games in Paris, France.

Two staff members from the South African Doping Control Laboratory (SADoCoL) which is housed at the University of the Free State (UFS), have been selected to work at the upcoming Olympic and Paralympic Games, in Paris, France.

Elandré Williams and Betsie Human will support the Paris laboratory during both games. The Olympic Games will take place from 26 July to 11 August 2024 and the Paralympic Games from 28 August to 8 September 2024.

Williams will be involved in steroid profile analysis, which includes sample preparation, analysis and data processing by Gas Chromatography (GC) and Isotope Ratio Mass Spectrometry (GC-C-IRMS).

Part of the fight against doping 

“I am excited, optimistic and privileged to have been given this opportunity, but I have to say that I am also quite nervous as this is most probably the biggest sporting event of the year. Being a part of the fight against doping in sport remains a great responsibility as what we do directly impacts the athletes,” says Williams.

She says is looking forward to the entire experience, from doing what she loves on an international level, meeting other analysts in the field and being part of the fight against doping in sport on an Olympic level.

This is her first big international sporting event.

“I am also looking forward to learning from other experts in the field who have more experience and to witness the procedures and the manner in which the laboratory operates at this time where the sample numbers are extremely high with the added pressure to finalise results in short turn-around times. This is a great opportunity for growth, both individually and in my field of expertise, in the scientific and the doping control field.

“It will definitely be an advantage for me as an analyst to get exposure to how the entire analytical procedure is executed in another laboratory, as well as insight into possible new techniques and advancements that I will be able to apply back at SADoCoL. I also think this is a great way to improve my ideas, perspectives and level of expertise as I will be working and witnessing other scientific experts in the doping control field.”

Managing workflow and logistics at the Games

Human, who was an analyst at the 2010 Soccer World Cup in South Africa, says she is both nervous and excited for this experience. 

“I was a junior analyst at SADoCoL during the 2010 Soccer World Cup, but you cannot compare a single-sport discipline with a multisport discipline like the Olympic Games – The Games will be exponentially bigger.

“In the past 14 years doping control as a whole has grown significantly. New technologies, updated requirements, more sensitive testing methods have emerged – this will be a new experience,” says Human.

She will also be involved with sample preparation/analysis/data processing and says she is looking forward to seeing how the work-flow and logistics associated with the Games (massive amounts of samples/tight deadlines etc) is managed in a high through-put laboratory.

“I am of course also looking forward to meeting analysts from other labs – we are a bit secluded here at the southern tip of Africa. Collaboration between labs is tricky when your closest neighbour is in Europe.

“It is always eye-opening to see how other labs manage similar situations (even though an Olympics is quite different from normal routine days) – exposure to new techniques and alternative thinking has a way of elevating your own thought processes and it promotes growth – both as an individual and as a doping control analyst.”

Immensely proud

Hanno du Preez, Director of SADoCoL, says the laboratory personnel are immensely proud that two of their staff members were chosen to participate in this international event, which for many scientists is the peak of their career. Similarly, this provides acknowledgement to the staff members for the area in which they have been working.

“It is only a select few who are requested to provide service at the Olympic Games. The work conducted in an Olympic laboratory provides experience which cannot be gained elsewhere. The workload and fast-paced analysis is something which the personnel are used to, but the Olympics will bring a different dimension to the processes. 

“We are excited to see what Betsie and Elandré bring back, with regards to new viewpoints on processes which are similar in all anti-doping laboratories. Individual experiences uplift everyone in a regulated business unit such as SADoCoL and also ensures improved relationships between laboratories, as other anti-doping laboratories will be represented at the Games as well. We wish them all the best for the experience, and we thank them for being dedicated ambassadors for SADoCoL and the UFS.”

News Archive

Newly operational sequencing unit in genomics at UFS
2016-09-09

Description: Next Generation Sequencing  Tags: Next Generation Sequencing

Dr Martin Nyaga and his research assistant,
Tshidiso Mogotsi in the Next Generation
Sequencing Laboratory.
Photo: Charl Devenish

The Next Generation Sequencing (NGS) unit at the UFS was established as an interdisciplinary facility under the Directorate for Research Development, Faculty of Health Sciences and Faculty of Natural and Agricultural Sciences.

The aim of the NGS facility is to aid internal and external investigators undertaking studies on Deoxyribonucleic acid (DNA) sequencing, assembly and bioinformatics approaches using the more advanced Illumina MiSeq NGS platform.

The NGS unit became operational in 2016 and is managed by Dr Martin Nyaga and administered through the office of the Dean, Faculty of Health Sciences, under the leadership of Prof Gert Van Zyl. Dr Nyaga has vast experience in microbial genomics, having done his PhD in Molecular Virology.

He has worked and collaborated with globally recognised centres of excellence in Prokaryotic and Eukaryotic genomics, namely the J. Craig Venter Institute and the Laboratory of Viral Metagenomics, Rega Institute, among others.

The unit has undertaken several projects and successfully generated data on bacterial, viral and human genomes. Currently, work is ongoing on bacterial and fungal metagenomics studies through 16S rRNA sequencing.

In addition, the unit is also working on plasmid/insert sequencing and whole genome sequencing of animal and human rotaviruses. The unit has capacity to undertake other kinds of panels like the HLA, Pan-cancer and Tumor 15 sequencing, among others.

Several investigators from the UFS including but not limited to Prof Felicity Burt, Prof Wijnand Swart, Dr Frans O’Neil, Dr Trudi O'Neill, Dr Charlotte Boucher, Dr Marieka Gryzenhout and Dr Kamaldeen Baba are actively in collaboration with the NGS unit.

The unit has also invested in other specialised equipment such as the M220 Focused-ultrasonicator (Covaris), 2100 Bioanalyzer system (Agilent) and the real-time PCR cycler, the Rotor-Gene Q (Qiagen), which both the UFS and external investigators can use for their research.

Investigators working on molecular and related studies are encouraged to engage with Dr Nyaga on how they would like to approach their genomics projects at the UFS NGS unit. 

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