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Prof Hendrik Swart
Prof Hendrik Swart’s prolific publication record, the high impact of his work, and the outstanding quality of his scholarly contributions have placed him among the top 0,05% of all scholars worldwide.

ScholarGPS awarded Prof Hendrik Swart, Senior Professor in the Department of Physics at the University of the Free State (UFS), Highly Ranked Scholar status.

ScholarGPS celebrates Highly Ranked Scholars™ for their performance in various fields, disciplines, and specialties. Prof Swart’s prolific publication record, the high impact of his work, and the outstanding quality of his scholarly contributions have placed him among the top 0,05% of all scholars worldwide.

Prof Swart received Highly Ranked Scholar status (Lifetime) for ranking 16th in the discipline of Phosphor. Highly Ranked Scholars™ – Lifetime refers to distinguished authors, including those who are currently active, retired, or deceased. These scholars are recognised for their exceptional lifetime scholarly contributions, placing them in the top 0,05% of all scholars. Their achievements are evaluated across four categories: overall (across all fields), within their specific field of study, within their particular discipline, and across all specialties they are associated with.

Additionally, Prof Swart received Highly Ranked Scholar status (prior five years) for ranking first in Condensed Matter Physics, 42nd in Physics, 155th in Sensor, 207th in Physical Science and Mathematics, and 969th in all fields.

Scientific profile and credibility

ScholarGPS is a California-based company that applies artificial intelligence, data mining, machine learning, and other data science techniques to its massive database of more than 200 million publications and 3 billion citations to rank more than 30 million scholars and 55 000 institutions worldwide. They categorise more than 200 million scholarly publications into specific academic specialties. These specialties are further organised into 177 disciplines and 14 overarching fields. As a result of this extensive classification effort, scholars who are considered highly ranked within their respective fields can now be identified with greater precision. This identification is done not only within each academic specialty, but also across disciplines and fields, providing a comprehensive view of scholarly achievement and expertise. This system allows for the identification of top scholars within various areas of academic research in a way that was not possible before.

Prof Swart, who is an NRF B1-rated researcher, currently also holds the SARChI Research Chair: Solid-state Luminescent and Advanced Materials (2023-2027). On receiving this award from ScholarGPS, he says it is always a privilege to be recognised as one of the top scholars in your specific field, especially at this late stage of his career.

Professionally, Prof Swart says this award may boost his scientific profile and credibility in the academic community, potentially leading to more collaborations and partnerships.

In the field of condensed matter physics, the impact of his work is specifically noteworthy in the study of defects and impurities within semiconductors, along with their practical applications in optoelectronic devices. Moreover, his significant contributions extend to understanding optical and electronic properties at the nanoscale, bearing implications for the development of semiconductor technology, including light-emitting diodes (LEDs), photovoltaic cells, and quantum dots.

Primarily focused on mentorship

He believes his successes in physics and advances in understanding the universe are the result of a combination of variables, including innovative research, collaboration and networking, mentorship, effective communication, persistence, and resilience. “I am primarily focused on mentorship, which is critical to developing the next generation of physicists and creating a supportive environment for learning and discovery, as well as conducting groundbreaking research and making novel discoveries that are critical to pushing the boundaries of physics. I am always searching for opportunities to collaborate with other scholars, both inside and outside my discipline, which will result in constructive exchange of ideas, interdisciplinary discoveries, and collective problem solving.”

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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