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10 June 2024 | Story Precious Shamase | Photo Supplied
Prof Richard Ocaya
Prof Richard Ocaya, Associate Professor from the Physics Department.

Prof Richard Ocaya from the Faculty of Natural and Agricultural Sciences at the University of the Free State (UFS) Qwaqwa  Campus has achieved a significant milestone with a newly patented invention. This patent, developed in collaboration with researchers from Turkey and Saudi Arabia, is the result of work that began in 2017, focusing on a special material known as graphitic carbon nitride.

This breakthrough in temperature measurement technology aligns perfectly with the university's Vision 130 commitment to innovation and addressing global challenges. The new device offers a unique solution to a longstanding issue in the field, providing accurate temperature measurements across an extremely wide range. Existing solutions often require multiple devices, leading to increased costs and reduced accuracy, but this invention simplifies the process.

The device, based on a combination of graphitic carbon nitride and silicon, can measure temperatures from -250°C to 250°C with exceptional consistency and linearity. This range and accuracy set it apart from current technologies, making it suitable for various applications, from standard temperature measurement to specialized settings involving extreme temperatures. It could be especially valuable in deep-space exploration, where equipment faces drastic temperature fluctuations.

The patent underscores the university's commitment to fostering collaborative research, a key aspect of Vision 130. Prof Ocaya attributes the success of the invention to the robust nature of the team, established in 2015. The team is now seeking to commercialize the technology by licensing it to a suitable partner, with organizations like NASA expected to show significant interest.

Prof Ocaya advises other academics considering patenting their inventions to ensure the patent solves a real problem uniquely and is based on sound principles. This makes the invention reproducible and protects it from being copied, assigning exclusive rights to the patent holder. Patenting allows for either manufacturing the devices or licensing them to third parties for royalties and profit. He notes that the main consideration is that the innovation must be practical and solve a specific problem in a novel and commercially viable way. He also acknowledges the challenge many academics face, as the "publish or perish" mentality often leads to choosing scientific articles over patents.

Despite securing the patent, Prof Ocaya and his team continue their research efforts, exploring new possibilities while balancing practical research with academic pursuits. He believes the invention will significantly impact the field of temperature measurement, being integrated into many new designs requiring such measurements.

The university proudly supports this innovative research and anticipates its real-world impact, furthering Vision 130's commitment to increasing UFS's research capacity and capability.

News Archive

Link between champagne bubbles and the UFS?
2012-11-16

Prof. Lodewyk Kock with an example of a front page of the publication FEMS Yeast Research, as adapted by F. Belliard, FEMS Central Office.
Photo: Leatitia Pienaar
15 November 2012

What is the link between the bubbles in champagne and breakthrough research being done at the Mayo Clinic in America? Nano research being done at our university.

Prof. Lodewyk Kock of Biotechnology says a human being consists of millions of minute cells that are invisible to the eye. The nano technology team at the UFS have developed a technique that allows researchers to look into such a cell, as well as other microorganisms. In this way, they can get an idea of what the cell’s “insides” look like.

The UFS team – consisting of Profs. Kock, Hendrik Swart (Physics), Pieter van Wyk (Centre for Microscopy), as well as Dr Chantel Swart (Biotechnology), Dr Carlien Pohl (Biotechnology) and Liza Coetsee (Physics) – were amazed to see that the inside of cells consist of a maze of small tunnels or blisters. Each tunnel is about 100 and more nanometres in diameter – about one ten thousandth of a millimetre – that weaves through the cells in a maze.

It was also found that these tunnels are the “lungs” of the cells. Academics doing research on yeast have had to sit up and take notice of the research being done at the UFS – to the extent that these “lungs” will appear on the front page of the highly acclaimed FEMS Yeast Research for all of 2013.

The Mayo Clinic, in particular, now wants to work with the UFS to study cancer cells in more detail in order to fight this disease, says Prof. Kock. The National Cancer Institute of America has also shown interest. This new nano technology for biology can assist in the study and development of nano medicine that can be used in the treatment of cancer and other life threatening diseases. Nano medicine uses nano metal participles that are up to one billionth of a metre in size.

Prof. Kock says laboratory tests indicate that nano medicine can improve the efficacy of anti-cancer medicine, which makes the treatment less toxic. “According to the Mayo Clinic team, nano particles are considered as a gold cartridge which is being fired directly at a cancer tumour. This is compared to fine shot that spreads through the body and also attacks healthy cells.”

“This accuracy implies that the chemotherapy dose can be lowered with fewer side effects. The Mayo Clinic found that one-tenth of the normal dosage is more effective against pancreas cancer in this way than the full dosage with a linkage to nano particles. According to the clinic, this nano medicine could also delay the spread of cancer,” says Prof. Kock.

The nano particles are used as messengers that convey anti-cancer treatment to cancer cells, where it then selectively kills the cancer cells. The transport and transfer of these medicines with regard to gold nano particles can be traced with the UFS’s nano technology to collect more information, especially where it works on the cell.

“With the new nano technology of the UFS, it is possible to do nano surgery on the cells by slicing the cells in nanometre thin slices while the working of the nano medicine is studied. In this way, it can be established if the nano medicine penetrates the cells or if it is only associated with the tiny tunnels,” says Prof. Kock.

And in champagne the small “lungs” are responsible for the bubbles. The same applies to beer and with this discovery a whole new reach field opens for scientists.

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