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10 June 2024 | Story Precious Shamase | Photo Supplied
Prof Richard Ocaya
Prof Richard Ocaya, Associate Professor from the Physics Department.

Prof Richard Ocaya from the Faculty of Natural and Agricultural Sciences at the University of the Free State (UFS) Qwaqwa  Campus has achieved a significant milestone with a newly patented invention. This patent, developed in collaboration with researchers from Turkey and Saudi Arabia, is the result of work that began in 2017, focusing on a special material known as graphitic carbon nitride.

This breakthrough in temperature measurement technology aligns perfectly with the university's Vision 130 commitment to innovation and addressing global challenges. The new device offers a unique solution to a longstanding issue in the field, providing accurate temperature measurements across an extremely wide range. Existing solutions often require multiple devices, leading to increased costs and reduced accuracy, but this invention simplifies the process.

The device, based on a combination of graphitic carbon nitride and silicon, can measure temperatures from -250°C to 250°C with exceptional consistency and linearity. This range and accuracy set it apart from current technologies, making it suitable for various applications, from standard temperature measurement to specialized settings involving extreme temperatures. It could be especially valuable in deep-space exploration, where equipment faces drastic temperature fluctuations.

The patent underscores the university's commitment to fostering collaborative research, a key aspect of Vision 130. Prof Ocaya attributes the success of the invention to the robust nature of the team, established in 2015. The team is now seeking to commercialize the technology by licensing it to a suitable partner, with organizations like NASA expected to show significant interest.

Prof Ocaya advises other academics considering patenting their inventions to ensure the patent solves a real problem uniquely and is based on sound principles. This makes the invention reproducible and protects it from being copied, assigning exclusive rights to the patent holder. Patenting allows for either manufacturing the devices or licensing them to third parties for royalties and profit. He notes that the main consideration is that the innovation must be practical and solve a specific problem in a novel and commercially viable way. He also acknowledges the challenge many academics face, as the "publish or perish" mentality often leads to choosing scientific articles over patents.

Despite securing the patent, Prof Ocaya and his team continue their research efforts, exploring new possibilities while balancing practical research with academic pursuits. He believes the invention will significantly impact the field of temperature measurement, being integrated into many new designs requiring such measurements.

The university proudly supports this innovative research and anticipates its real-world impact, furthering Vision 130's commitment to increasing UFS's research capacity and capability.

News Archive

Collaboration between UFS and Mayo Clinic to revolutionise cancer treatment
2014-06-27



Attending the lecture were, from the left: Dr Chantel Swart, Prof Lodewyk Kock, Prof Debabrata Mukhopadhyay, Prof James du Preez; back: Prof Pieter van Wyk.
Dr Swart, Profs Kock and Du Preez are from the Department of Microbial, Biochemical and Food Biotechnology. Prof Mukhopadhyay is from the Mayo Clinic (US) and Prof Van Wyk is from the Centre for Microscopy at the UFS.
Photo: Supplied
The UFS made a discovery that may have enormous implications for the treatment of diseases in humans.

Since the discovery, the UFS joined forces with the Mayo Clinic in Rochester, US, in the fight against cancer.

In this collective effort, UFS researchers would be able to assist the Mayo team to:
• see how treatment in cancer patients is progressing,
• target treatments more effectively,
• reduce dosages in order to make treatment gentler on the patient,
• track the effectiveness of the chemotherapy drugs used, and
• gain an accurate view of how the cancer is being eliminated.

Prof Lodewyk Kock, Outstanding Professor at the Department of Microbial, Biochemical and Food Biotechnology, and his team incidentally created a technique to use argon gas particles for the first time on biological material to slice open cells to look inside.

The team that supported Prof Kock includes Dr Chantel Swart, Khumisho Dithebe (PhD student), Prof Hendrik Swart (Department of Physics) and Prof Pieter van Wyk (Centre for Microscopy).

Prof Debabrata Mukhopadhyay from the Mayo Clinic in Rochester, US, got to hear about this breakthrough at the UFS and a collaboration between the two institutions was established.

During a visit to the Bloemfontein Campus, Prof Mukhopadhyay explained novel techniques that make use of gold nanoparticles. These particles attach to chemotherapeutic drugs to selectively target cancer cells – dramatically decreasing the side effects to normal human cells.

For these new drugs (coupled to gold nanoparticles) to be accepted into clinical practice, visual and chemical proof is needed, though. This is where the technique developed by the UFS will play a vital role.

With the technique to look inside cells, the composition, location and metabolism of these drugs can be determined. This will aid in a proof of concept for the application of the nano-drugs. Furthermore, it will enable approval for use of these drugs in clinical trials and eventually could revolutionise cancer treatment as a whole.

For video lectures on the technique used, as well as its findings, follow these links:

1. http://vimeo.com/63643628 (Comic version for school kids)

2. http://vimeo.com/61521401 (Detailed version for fellow scientists)

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