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UFS student thrives in exchange programme with the University of Debrecen

14 June 2024 | Story Anthony Mthembu | Photo Suplied

As part of an exchange initiative facilitated by the Erasmus+ Mobility Programme, Jeremiah Hlahla, a student at the University of the Free State (UFS), is nearing the completion of his PhD studies at the University of Debrecen in Hungary. Hlahla’s journey, which began in February 2024 and is set to conclude in July 2024, has been a remarkable learning opportunity. “As a first time-traveller to Europe, I have thoroughly enjoyed engaging with people from different countries and cultures,” he said.

The benefits of international collaboration

Hlahla is currently pursuing a PhD in Botany, focusing on plant stress physiology. “My current PhD project investigates the physiological, biochemical and morphological responses of vegetable-type soybean, or edamame, to combined drought and heat stress,’’ he explained. He considers the University of Debrecen the ideal institution to complete his research due to its extensive expertise and resources in similar projects. He noted that his colleagues at Debrecen conduct significant work on plant protection against biotic and abiotic stresses, including salt and drought stress, as well as proteins and amino acids in barley and other legumes.

Given the vast knowledge available on similar projects, Hlahla has found substantial engagement with his work at the University of Debrecen. “Upon arrival, I delivered an introductory lecture presenting my UFS project on the synergistic effects of combined drought and heat stress on the physiology and biochemistry of edamame. It was an engaging session as everyone could relate to my work and asked many questions,’’ he said.

Insights gained from the exchange

Hlahla has also gained valuable lessons that will assist him in his research career, including biotechnology and physiology tools. “I learned how to prepare samples and use high-performance liquid chromatography (HPLC) and reversed-phase ultra-high-performance liquid chromatography (UHPLC) to quantify proteins and amino acids,’’ he said. These techniques are beneficial not only for his current work but will also support future soybean research.

As his experience at the University of Debrecen nears its end, Hlahla reflects on the collaborations and friendships he has formed, which stand out as a significant highlight.

News Archive

UFS boasts with most advanced chemical research apparatus in Africa

2005-11-23

Celebrating the inauguration of the NMR were from the left Prof Frederick Fourie (Rector and Vice-Chancellor of the UFS), Dr Detlef Müller (Development Scientist and Manager: Africa and Asia of Bruker in Germany, the supplier of the NMR), Prof Jannie Swarts (head of the head of the Division Physical Chemistry at the UFS) and Prof Herman van Schalkwyk (Dean: Faculty of Natural and Agricultural Sciences at the UFS). Photo: Lacea Loader

UFS boasts with most advanced chemical research apparatus in Africa

The University of the Free State’s (UFS) Department of Chemistry now boasts with some of the most advanced chemical research apparatus in Africa after the latest addition, a nuclear magnetic resonance (NMR) spectrometer, was inaugurated today by the Rector and Vice-Chancellor, Prof Frederick Fourie. The NMR is used to analyse molecular structures.

Last month the Department of Chemistry celebrated the installation of the most advanced single crystal X-ray diffractometer in Africa. The diffractometer provides an indispensable technique to investigate among others the solid state of compounds for medicinal application.

“Three years ago the UFS executive management realised that, if we want to build a university of excellence, we should invest in research. We started to think strategically about chemistry and decided to bring the apparatus at the Department of Chemistry on a more competitive standard. Strategic partnerships were therefore secured with companies like Sasol,” said Prof Fourie during the inauguration ceremony.

“The installation of the NMR symbolises the ability of the UFS to turn academic areas around. I hope that this is the beginning of a decade of excellence for chemistry at the UFS,” said Prof Fourie.

”The catalogue value of the Bruker 600 MHz NMR is approximately R11 million. With such an advanced apparatus we are now able to train much more post-graduate students,“ said Prof Jannie Swarts, head of the Division Physical Chemistry at the UFS.

”The NMR is the flagship apparatus of the UFS Department of Chemistry that enables chemists to look at compounds more easily at a molecular level. Research in chemistry is critically dependent on NMR, which is a technique that can determine the composition of reactants and products in complicated chemical reactions, with direct application is most focus areas in chemistry,“ said Prof Swarts.

”Parts of the spectrometer consists of non-commercial items that were specifically designed for the UFS Department of Chemistry to allow the study of unique interactions in e.g. rhodium and platinum compounds,” said Prof Swarts.

According to Prof Swarts the NMR enables chemists to conduct investigations on the following:

To evaluate for example the complex behaviour of DNA in proteins as well as the analysis of illegal drugs sometimes used by athletes.
It provides an indispensable technique to investigate compounds for medicinal application for example in breast, prostate and related bone cancer identification and therapy, which are currently synthesised in the Department of Chemistry.
It can also be applied to the area of homogeneous catalysis where new and improved compounds for industrial application are synthesized and characterised, whereby Sasol and even the international petrochemical industry could benefit. This analytical capacity is highly rated, especially in the current climate of increased oil prices.
The NMR can detect and identify small concentrations of impurities in feed streams in the petrochemical industry, e.g. at Sasol and also the international petrochemical industry. These minute amounts of impurities can result in metal catalyst deactivation or decomposition and can cause million of rands worth in product losses.
It is indispensable for studying the complexity of samples that is non-crystalline. These materials represent the vast majority of chemical compounds such as solvents, gasoline, cooking oil, cleaning agents and colorants as examples.

According to Prof Swarts the general medical technique of MRI (magnetic resonance imaging) in use at larger hospitals, is based on NMR technology.

”The NMR apparatus enabled the Department of Chemistry to characterise complex molecules that were synthesised for the multi-national company, FARMOFS-PAREXEL, and to negotiate research agreements with overseas universities,” said Prof Swarts.

Media release
Issued by: Lacea Loader
Media Representative
Tel: (051) 401-2584
Cell: 083 645 2454
E-mail: loaderl.stg@mail.uovs.ac.za
22 November 2005

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