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08 May 2024 Photo SUPPLIED
Dirk Opperman

The Dean of the Faculty of Natural and Agricultural Sciences, Prof Paul Oberholster, has the pleasure of inviting you to the inaugural lecture of Prof Dirk Opperman.

Date: 21 May 2024

Time: 17:30

Venue: Equitas

Click to view document Click here to RSVP before Wednesday, 15 May 2024. Alternatively, contact Christelle van Rooyen on +27 51 401 9190.

 

About Prof Dirk Opperman

Prof Dirk Opperman obtained his PhD in Biochemistry at the University of the Free State in 2008. This was followed by postdoctoral research on directed evolution with Prof Manfred T Reetz at the Max Planck Institute for Coal Research (Germany). In 2010, he was appointed in the Department of Microbiology and Biochemistry. He subsequently established structural biology at the UFS, and his current research focus lies at the interface of evolutionary and structure-function relationships of biocatalysts, and their application in green chemistry. He is an NRF B-rated researcher with co-authored papers in Science, Nature Communications, and Angewandte Chemie.

His research has been funded by both local and international organisations, ranging from industries such as SASOL to the Global Challenges Research Fund (GCRF, UK). He has a long-standing collaboration with researchers at the Delft University of Technology (TUDelft, the Netherlands) and is currently part of a European Research Area Network Cofund (ERA-NET Cofund) partnership on Food Systems and Climate (FOSC) that develops biocatalysts for upcycling waste.

News Archive

Medical team performs first hybrid procedure in the Free State
2014-12-08

The days when a heart operation meant hours in an operating theatre, with weeks and even months of convalescing, will soon be something of the past.

A team of cardiologists from the University of the Free State’s (UFS) Faculty of Health Sciences once again made medical history when they performed the first hybrid procedure in the Free State.

The Department of Paediatric Cardiology, in conjunction with the Department of Cardiothoracic Surgery, performed this very successful procedure on a 45-year-old woman from Kuruman.

During the procedure of 30 minutes, the patient’s thorax was opened up through a mini thoracotomy to operate on the beating heart.

“The patient received an artificial valve in 2011. Due to infection, a giant aneurism developed from the left ventricle, next to the aorta. Surgery would pose a very high risk to the patient. Furthermore, her health was such that it would contribute to problems during open-heart surgery,” explains Prof Stephen Brown, Head of the UFS’s Department of Paediatric Cardiology.

“After the heart was opened up through a mini thoracotomy, the paediatric cardiologists performed a direct puncture with a needle to the left ventricle cavity. A Special sheath was then placed in the left ventricle to bypass the catheters. Aided by highly advanced three-dimensional echocardiography and dihedral X-ray guidance, the opening to the aneurism, located directly below the artificial aorta valve, was identified and the aneurism cannulated.”
 
During the operation, a special coil, called a Nester Retractor, was used for the first time on a patient in South Africa to obtain stasis of extravasation and ensure the stability of devices in the aneurism.

“This is highly advanced and specialist work, as we had to make sure that the aneurism doesn’t rupture during manipulation and the devices had to be positioned in such a way that it doesn’t cause obstruction in valve function or the coronary artery. The surgical team was ready all the time to switch the patient to the heart-lung machine should something go wrong, but the procedure was very successful and the patient was discharged after a few days.”

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