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08 May 2024
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The Dean of the Faculty of Natural and Agricultural Sciences, Prof Paul Oberholster, has the pleasure of inviting you to the inaugural lecture of Prof Dirk Opperman.
Date: 21 May 2024
Time: 17:30
Venue: Equitas
Click here to RSVP before Wednesday, 15 May 2024. Alternatively, contact Christelle van Rooyen on +27 51 401 9190.
About Prof Dirk Opperman
Prof Dirk Opperman obtained his PhD in Biochemistry at the University of the Free State in 2008. This was followed by postdoctoral research on directed evolution with Prof Manfred T Reetz at the Max Planck Institute for Coal Research (Germany). In 2010, he was appointed in the Department of Microbiology and Biochemistry. He subsequently established structural biology at the UFS, and his current research focus lies at the interface of evolutionary and structure-function relationships of biocatalysts, and their application in green chemistry. He is an NRF B-rated researcher with co-authored papers in Science, Nature Communications, and Angewandte Chemie.
His research has been funded by both local and international organisations, ranging from industries such as SASOL to the Global Challenges Research Fund (GCRF, UK). He has a long-standing collaboration with researchers at the Delft University of Technology (TUDelft, the Netherlands) and is currently part of a European Research Area Network Cofund (ERA-NET Cofund) partnership on Food Systems and Climate (FOSC) that develops biocatalysts for upcycling waste.
Fighting the tuberculosis battle as a collective
2015-09-28

The team hard at work making South Africa a healthier place |
Tuberculosis (TB) is second only to HIV/AIDS as the greatest killer worldwide due to a single infectious agent. More than 95% of TB deaths occur in low- and middle-income countries. Despite being more prevalent among men than women, TB remains one of the top five causes of death amongst women between the ages of 15 and 44 years. While everyone is at risk for contracting TB, those most at risk include children under the age of five and the elderly. In addition, research indicates that individuals with compromised immune systems, household contacts with pulmonary TB patients, and healthcare workers are also at increased risk for contracting TB.
According to the Deputy Director of the Centre for Health Systems Research and Development (CHSR&D) at the UFS, Dr Michelle Engelbrecht, research has found that healthcare workers may be three times more likely to be infected by TB than the general population.
The unsettling fact
“Research done in health facilities in South Africa has found that nurses do not often participate in basic prevention acts, such as opening windows and wearing respirators when attending to infectious TB patients,” she explained.
In response to this concern, CHSR&D, which operates within the Faculty of Humanities at the the University of the Free State (UFS) Bloemfontein Campus has developed a research project to investigate TB prevention and infection control in primary healthcare facilities and households in Mangaung Metropolitan.
Action to counter the statistics
A team of four researchers and eight field workers from CHSR&D are in the process of gathering baseline data from the 41 primary healthcare facilities in Mangaung. The baseline comprises a facility assessment conducted with the TB nurse, and observations at each of the facilities. Individual interviews are also conducted with community caregivers, as well as TB and general patients. Self-administered questionnaires on knowledge, attitudes, and practices about TB infection control are completed by all nurses and facility-based community caregivers.
Healthcare workers are the main focus of this research, given their increased risk of acquiring TB in healthcare settings. At clinics, interventions will be developed to improve infection control practices by both healthcare workers and patients. TB patients’ households are also visited to screen household contacts for TB. Those found to have symptoms suggesting TB infection are referred to the clinics for further assessment and treatment.
The findings of this study will serve to inform the development of an intervention to address TB prevention and infection control in primary healthcare facilities. Further funding will be sought to implement and evaluate the intervention.
Curbing future infections and subsequent deaths as a result of TB is the priority for the UFS. The cooperation and collaboration of the community, government, and sponsors will ensure that this project is a success, hence prolonging life expectancy.