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08 May 2024 Photo SUPPLIED
Dirk Opperman

The Dean of the Faculty of Natural and Agricultural Sciences, Prof Paul Oberholster, has the pleasure of inviting you to the inaugural lecture of Prof Dirk Opperman.

Date: 21 May 2024

Time: 17:30

Venue: Equitas

Click to view document Click here to RSVP before Wednesday, 15 May 2024. Alternatively, contact Christelle van Rooyen on +27 51 401 9190.

 

About Prof Dirk Opperman

Prof Dirk Opperman obtained his PhD in Biochemistry at the University of the Free State in 2008. This was followed by postdoctoral research on directed evolution with Prof Manfred T Reetz at the Max Planck Institute for Coal Research (Germany). In 2010, he was appointed in the Department of Microbiology and Biochemistry. He subsequently established structural biology at the UFS, and his current research focus lies at the interface of evolutionary and structure-function relationships of biocatalysts, and their application in green chemistry. He is an NRF B-rated researcher with co-authored papers in Science, Nature Communications, and Angewandte Chemie.

His research has been funded by both local and international organisations, ranging from industries such as SASOL to the Global Challenges Research Fund (GCRF, UK). He has a long-standing collaboration with researchers at the Delft University of Technology (TUDelft, the Netherlands) and is currently part of a European Research Area Network Cofund (ERA-NET Cofund) partnership on Food Systems and Climate (FOSC) that develops biocatalysts for upcycling waste.

News Archive

HIV Cure – Just another fantasy?
2016-07-27

Description: HIV Cure – Just another fantasy? Tags: HIV Cure – Just another fantasy?

Dr Dominique Goedhals, Prof John Frater,
Dr Thabiso Mofokeng and Dr Jacob Jansen van Vuuren,
attended the lecture. Prof Frater has been working in
collaboration with the UFS Department of Internal
Medicine on HIV resistance and HIV immunology
since 2007.

Photo: Nonsindiso Qwabe

Twenty-years ago, after a person had been diagnosed with HIV, their lifespan did not exceed three years, but thanks to the success of antiretroviral therapy programmes, life expectancy has risen by an average of ten years. However, is antiretroviral therapy always going to be for life? This is the societal issue that Professor John Frater, addressed in his talk at the University of the Free State. He is an MRC Senior Clinical Fellow, Associate Professor and Honorary Consultant Physician in Infectious Diseases at  Oxford University.

Antiretroviral medicine therapeutic

The discovery of antiretroviral therapy - the use of HIV medicines to treat the virus - has had a positive effect on the health and well-being of people living with it, improving their quality of life. Unfortunately, if treatment is stopped, HIV rebounds to the detriment of the patient. Now, research has shown that some patients, who are treated soon after being infected by HIV, may go off treatment for prolonged periods. Work is being done to predict who will be able to stop treatment.

“The difference made by starting treatment earlier is enormous. Delaying treatment is denying yourself the right to health,” Professor Frater says. However, this does not mean that the virus is cured. “A person can live for ten years without being on HIV treatment, but is that enough?” he went on to ask.

Healthy lifestyles encouraged

The National Department of Health will adopt a test and treat immediately strategy later this year to improve patient health and curb the spread of HIV. ,This is another reason why everybody should know their status and start treatment as soon as possible.

Search for a cure continues

More research is being conducted to establish whether HIV can be eradicated. Remission gives hope that a permanent cure may be found eventually. “Will a cure for HIV ever be found? Time will tell,” he concluded.

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