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12 November 2024 | Story Jacky Tshokwe | Photo Supplied
Dr Mariana Erasmus
Dr Mariana Erasmus (Vice Director, CMBG) demonstrates some of the equipment in the newly established, state-of-the-art laboratories at the Centre for Mineral Biogeochemistry.

The University of the Free State (UFS) recently hosted a landmark event-the national launch of the South African Biogeochemistry Research Infrastructure Platform (BIOGRIP) - in the Centenary Complex on its Bloemfontein Campus. This significant occasion marked the establishment of the Centre for Mineral Biogeochemistry at the UFS and underscored South Africa’s growing commitment to biogeochemistry research.

Prof Anthea Rhoda welcomed the distinguished gathering of scientists, students, industry leaders, and stakeholders, highlighting the launch as a collaborative milestone in South Africa's scientific journey. In her address, Prof Rhoda emphasised the importance of the interdisciplinary nature of biogeochemistry, where biology, geology, and chemistry converge to offer insights into critical issues such as climate change, water quality, and soil health. She remarked on the necessity of collaboration, explaining that BIOGRIP’s platform, built on shared resources and expertise, exemplifies the power of uniting across institutional boundaries to accelerate impactful discoveries.

The programme featured insightful scientific talks by leading experts, each focusing on how biogeochemistry addresses key environmental issues such as sustainability and resource management. These presentations reinforced BIOGRIP’s commitment to advancing knowledge that can influence policy and improve practices.

Attendees were also given guided tours of the state-of-the-art laboratories in the Centre for Mineral Biogeochemistry, which provided a behind-the-scenes look at the advanced tools and methods employed in studying interactions between minerals, biology, and the environment. For many, this was a highlight, as they observed firsthand how biogeochemical research is conducted and contributes to soil health, pollution control, and environmental conservation.

The launch provided ample networking opportunities, fostering connections among academics, government representatives, industry professionals, and environmental organisations. Over a catered lunch, participants engaged in vibrant discussions about potential collaborations and the role of biogeochemistry in addressing South Africa’s environmental challenges.

The BIOGRIP national launch stands as a milestone event, not only for the UFS, but for the broader South African scientific community. With the establishment of this research platform, South Africa is well-positioned to tackle pressing environmental issues through innovative research and cross-sector collaboration. The event left attendees inspired and motivated, setting an optimistic tone for the future of biogeochemistry research in the region.

News Archive

UFS cardiac team leading with project
2017-05-31

 Description: Cardiac team read more Tags: Cardiac team read more

Prof Peter Schultheiss of the Charité University in Berlin,
Germany, visited the Robert WM Frater Centre for
Cardiovascular Research at the UFS for a study regarding
cardiomyopathy, a significant cause of fatal heart failure
among Africans. From the left are Dr Glen Taylor,
Dr Danie Buys, Prof Makoali Makatoko,
Prof Schultheiss and Prof Francis Smit.
Photo: Rulanzen Martin

A team of cardiac doctors associated with the Robert WM Frater Cardiovascular Research Centre at the University of the Free State’s (UFS) Faculty of Health Sciences has commenced with a pioneering research project regarding idiopathic dilating cardiomyopathy.  

An Afrocentric research focus
Prof Francis Smit, Head of the Department of Cardiothoracic Surgery at the UFS and Head of the Frater Centre, describes dilating cardiomyopathy as a heart muscle disease that is quite common, particularly among people of African descent. The disease weakens the heart muscle, which in turn leads to heart failure.

“To date there is no curable treatment for this condition and 50% of patients that have shown heart failure, died within a period of five years. The causes of this condition have been unknown in the majority of patients. But over the past few years major strides have been made where virus infections of the heart muscle or myocarditis have been identified as a possible underlying cause. Various genetic diseases are also linked to it,” says Prof Smit.

International collaborations ensure success
According to Prof Smit, the project is being run in conjunction with Prof Heinz-Peter Schultheiss of the Charité University and the Institute for Cardiac Diagnostics and Therapy in Berlin, Germany.

“We have been working on the project over the past 18 months and I have twice visited Prof Schultheiss in Germany. He is now visiting us in Bloemfontein. We have established a collaborative project focused on patients in central South Africa”.
Prof Schultheiss is a world leader regarding the diagnosis, pathology and treatment of dilating cardiomyopathy, says Prof Smit.

“He brings a lifetime of research experience to Bloemfontein and is internationally renowned as the father of myocardial or heart muscle biopsies.

“His pioneering work on the discipline has led to diagnostic accuracy that has induced purposeful and personalised treatment of dilating cardiomyopathy and has brought about dramatic changes in some subsets of patients’ life expectancy and their cure.”

Solving problems close to home
According to Prof Mokoali Makatoko, Head of the Department of Cardiology, there are more than 1500 new cases of heart failure identified annually at the Universitas Academic Hospital, of which approximately 30% are attributed to cardiomyopathy. “With the use of endomyocardial biopsies the team hopes to treat viruses unique to Southern Africa as well as other underlying causes of dilating cardiomyopathy.”

Prof Stephen Brown, Head of Paediatric Cardiology at the Universitas Academic Hospital, says children suffering from this disease never reach a mature age and those under his supervision will also be undergoing these tests. Various other departments at the UFS will also participate in this project. Profs Makatoko and Brown did the first four endomyocardial biopsies under the management of Prof Schultheiss during the past week. The results will be available in the coming weeks after which the project will be officially launched and patient recruitment will start in earnest.

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