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12 November 2024 | Story Jacky Tshokwe | Photo Supplied
Dr Mariana Erasmus
Dr Mariana Erasmus (Vice Director, CMBG) demonstrates some of the equipment in the newly established, state-of-the-art laboratories at the Centre for Mineral Biogeochemistry.

The University of the Free State (UFS) recently hosted a landmark event-the national launch of the South African Biogeochemistry Research Infrastructure Platform (BIOGRIP) - in the Centenary Complex on its Bloemfontein Campus. This significant occasion marked the establishment of the Centre for Mineral Biogeochemistry at the UFS and underscored South Africa’s growing commitment to biogeochemistry research.

Prof Anthea Rhoda welcomed the distinguished gathering of scientists, students, industry leaders, and stakeholders, highlighting the launch as a collaborative milestone in South Africa's scientific journey. In her address, Prof Rhoda emphasised the importance of the interdisciplinary nature of biogeochemistry, where biology, geology, and chemistry converge to offer insights into critical issues such as climate change, water quality, and soil health. She remarked on the necessity of collaboration, explaining that BIOGRIP’s platform, built on shared resources and expertise, exemplifies the power of uniting across institutional boundaries to accelerate impactful discoveries.

The programme featured insightful scientific talks by leading experts, each focusing on how biogeochemistry addresses key environmental issues such as sustainability and resource management. These presentations reinforced BIOGRIP’s commitment to advancing knowledge that can influence policy and improve practices.

Attendees were also given guided tours of the state-of-the-art laboratories in the Centre for Mineral Biogeochemistry, which provided a behind-the-scenes look at the advanced tools and methods employed in studying interactions between minerals, biology, and the environment. For many, this was a highlight, as they observed firsthand how biogeochemical research is conducted and contributes to soil health, pollution control, and environmental conservation.

The launch provided ample networking opportunities, fostering connections among academics, government representatives, industry professionals, and environmental organisations. Over a catered lunch, participants engaged in vibrant discussions about potential collaborations and the role of biogeochemistry in addressing South Africa’s environmental challenges.

The BIOGRIP national launch stands as a milestone event, not only for the UFS, but for the broader South African scientific community. With the establishment of this research platform, South Africa is well-positioned to tackle pressing environmental issues through innovative research and cross-sector collaboration. The event left attendees inspired and motivated, setting an optimistic tone for the future of biogeochemistry research in the region.

News Archive

Newly operational sequencing unit in genomics at UFS
2016-09-09

Description: Next Generation Sequencing  Tags: Next Generation Sequencing

Dr Martin Nyaga and his research assistant,
Tshidiso Mogotsi in the Next Generation
Sequencing Laboratory.
Photo: Charl Devenish

The Next Generation Sequencing (NGS) unit at the UFS was established as an interdisciplinary facility under the Directorate for Research Development, Faculty of Health Sciences and Faculty of Natural and Agricultural Sciences.

The aim of the NGS facility is to aid internal and external investigators undertaking studies on Deoxyribonucleic acid (DNA) sequencing, assembly and bioinformatics approaches using the more advanced Illumina MiSeq NGS platform.

The NGS unit became operational in 2016 and is managed by Dr Martin Nyaga and administered through the office of the Dean, Faculty of Health Sciences, under the leadership of Prof Gert Van Zyl. Dr Nyaga has vast experience in microbial genomics, having done his PhD in Molecular Virology.

He has worked and collaborated with globally recognised centres of excellence in Prokaryotic and Eukaryotic genomics, namely the J. Craig Venter Institute and the Laboratory of Viral Metagenomics, Rega Institute, among others.

The unit has undertaken several projects and successfully generated data on bacterial, viral and human genomes. Currently, work is ongoing on bacterial and fungal metagenomics studies through 16S rRNA sequencing.

In addition, the unit is also working on plasmid/insert sequencing and whole genome sequencing of animal and human rotaviruses. The unit has capacity to undertake other kinds of panels like the HLA, Pan-cancer and Tumor 15 sequencing, among others.

Several investigators from the UFS including but not limited to Prof Felicity Burt, Prof Wijnand Swart, Dr Frans O’Neil, Dr Trudi O'Neill, Dr Charlotte Boucher, Dr Marieka Gryzenhout and Dr Kamaldeen Baba are actively in collaboration with the NGS unit.

The unit has also invested in other specialised equipment such as the M220 Focused-ultrasonicator (Covaris), 2100 Bioanalyzer system (Agilent) and the real-time PCR cycler, the Rotor-Gene Q (Qiagen), which both the UFS and external investigators can use for their research.

Investigators working on molecular and related studies are encouraged to engage with Dr Nyaga on how they would like to approach their genomics projects at the UFS NGS unit. 

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