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05 November 2024 | Story Leonie Bolleurs | Photo Supplied
BOOTES-6 telescope station
The BOOTES-6 telescope station captured a South African sighting of the southern lights, a rare atmospheric phenomenon powered by solar activity.

The northern lights, with their vibrant displays of green, pink, and violet hues, have become a famous attraction in Nordic countries. But in early October, a rare sighting of the southern lights – or aurora australis – was reported in South Africa, surprising many.

Prof Pieter Meintjes, Professor in the Department of Physics at the University of the Free State (UFS), explains that both the northern and southern lights are the result of charged particles from coronal mass ejections (CMEs) on the sun, which are captured by Earth’s magnetic field. "The interaction between magnetic fields and charged particles, such as protons and electrons, is very interesting. The magnetic field forces these particles to spiral around the field lines, ultimately guiding them towards the magnetic poles. As these particles enter Earth’s atmosphere, they collide with atmospheric atoms, causing a beautiful glow. The colours of the aurora indicate which atoms are involved. Typically, hydrogen shines red, while oxygen and nitrogen produce a greenish-blue tinge," he says.

Observing the southern lights

When the display occurs above the northern magnetic pole, it is called the aurora borealis (northern lights) and can typically be observed over regions such as Alaska, Greenland, and the Nordic countries. Above the southern magnetic pole, it is known as aurora australis (southern lights), usually visible over places such as Antarctica and New Zealand. “In extreme cases – when gigantic mass ejections occurred – it can also be observed in mid-latitudes such as South Africa,” says Prof Meintjes.

This recent and rare South African sighting was also captured by the BOOTES-6 telescope station at Boyden Observatory, located just outside Bloemfontein. According to Prof Meintjes, the telescope station has an all-sky monitor – a camera constantly watching the sky for changes and monitoring, among others, cloud cover to ensure that the telescope is always safe from weather. While the monitor was taking photos of the night sky, Prof Alberto Castro-Tirado, a research professor at the Institute of Astrophysics of Andalusia in Spain, picked up the aurora.

The Institute of Astrophysics of Andalusia in Spain, in collaboration with the University College Dublin (UCD), is partnering with the UFS in a research-driven initiative involving the BOOTES-6 telescope station, installed in 2022 during the COVID-19 pandemic. Under a Memorandum of Understanding that was recently renewed for another five years, the UFS and UCD share approximately 30% of the telescope's observing time dedicated to UFS research.

“The DPRT telescope (Dolores Pérez-Ramírez telescope), named after a Spanish astronomer and lecturer at the University of Jaén, contributes significantly to our research, with publications resulting from contributions made by the telescope station and collaborators on gamma-ray bursts, occultations, and transient events co-authored by me and a colleague in the department, Dr Hendrik van Heerden,” notes Prof Meintjes.

Research-driven initiatives

Data from the telescope station is also used for their in-house projects and contributes significantly to the work of their PhD students that will be submitted in the next few years. This includes the PhD work of Helene Szegedi, who uses data from the BOOTES-6 telescope station to study cataclysmic variable systems – compact binaries that erupt regularly. Another PhD student, Joleen Barnard, studies blazar variability under the guidance of Prof Brian van Soelen. Blazars, explains Prof Meintjes, are the core of distant galaxies powered by supermassive black holes. These cosmic jets are pointed towards Earth, but fortunately, they are millions or billions of light years away; otherwise, their impact would be devastating to life on Earth.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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