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29 November 2024 | Story Anthony Mthembu | Photo Tania Allan
Business School 25 Year Celebration
Some of the guests and staff members of the UFS Business School who attended the 25th anniversary celebration of the school.

To commemorate its 25th anniversary, the Business School at the University of the Free State (UFS) held a celebratory event on the UFS Bloemfontein Campus on 22 November 2024.

Prof Frans Prinsloo, acting Dean of the Faculty of Economic and Management Sciences (EMS) at the UFS who attended the event, said, “The occasion is not just a celebration of the passing of time, but it’s also an opportunity for us to reflect on the values, achievements, and aspirations that have shaped the journey of the UFS Business School.” The event, which was regarded as a ‘momentous milestone’, was also attended by Prof Nicolene Barkhuizen, Director of the UFS Business School, Prof Frederick Fourie and Prof Bennie Anderson – founding members of the Business School, as well as Prof Tienie Crous and Prof Hendri Kroukamp, who are former deans of EMS.

A walk down memory lane

In his opening address, Prof Prinsloo reflected on the growth of the Business School over the past 25 years and highlighted some of the achievements of the staff that make up the Business School. However, the highlight of the event for many in the audience was the trip down memory lane by the founding members of the Business School as well as the former deans of the faculty.

 In their address, Profs Fourie and Anderson shared some of their fondest memories and experiences as they worked towards putting together the Business School. For instance, Prof Fourie indicated that in order to ensure that the syllabus was of high quality, the founding members had to travel overseas and learn from several institutions, such as Harvard Business School.

In addition, Profs Fourie and Anderson spoke extensively about their pride in the Business Management and Leadership (BML) programme, offered by the Business School. According to Prof Fourie, the degree was the brainchild of Prof Anderson, who for several reasons wanted to consider working adults who might not have had experience in school learning. As such, they consider the BML programme as one of their most special achievements, given its impact. Furthermore, Prof Crous and Prof Kroukamp also shared their memories of being part of the institution, and specifically the Business School.

Forging ahead for another 25 years

In the pursuit of 25 more years, Prof Barkhuizen indicated that the school is aiming to achieve success with several projects. These include staff and student exchanges in order to optimise the experience of both stakeholders. “Even though we have a global reach, it is important for us to apply it locally,” she said. In addition, Prof Barkhuizen highlights that for the Business School to continue serving the needs of its unique student clientele, it needs to become more agile. As such, it will continuously reinvent its programmes with the input of its stakeholders. For instance, she indicated that the school is looking at implementing joint qualification offerings, among other things.

As the event ended, Prof Barkhuizen said that she was, “so proud of the progress made by the Business School; it has been a journey to get here, but this function today taught me to never give up hope and not to give up on one’s dreams”.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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