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Prof Per Assmo from University West, Sweden and Prof Anthea Rhoda from the UFS signed a Memorandum of Understanding that will develop academic cooperation across fields such as research, student and academic exchanges, and collaborative projects.

The University of the Free State (UFS) has signed a Memorandum of Understanding (MOU) with University West, Sweden. Held at the UFS Business School on the Bloemfontein Campus, the event saw the signing of the agreement by Prof Anthea Rhoda, acting UFS Vice-Chancellor and Principal, and Prof Per Assmo, Deputy Vice-Chancellor for Internationalisation at University West. The partnership aims to develop academic cooperation across fields such as research, student and academic exchanges, and collaborative projects.

This MOU opens the door to a wide range of collaborative initiatives, including academic and researcher exchanges for the purposes of teaching, conducting lectures, conducting research, and exchanging expertise. Additionally, the MOU includes student exchange programmes, joint research projects, and the shared hosting of seminars and conferences.

Prof Rhoda shared her enthusiasm to incorporate work-integrated learning (WIL) more widely at the UFS. “We are looking at work-integrated learning as an extension of engaged scholarship. It is something that we're looking forward to expanding,” she said.

Building a connected community

Prof Assmo explained that their institution, though small, has a unique approach that focuses on both production technology and work-integrated learning – a teaching model that goes beyond internships to provide students with practical, hands-on experience. "For us, WIL is a research field and academic discipline in its own right," he said.

University West is also the only university in the world to offer a PhD specifically in WIL, a programme it spent 20 years developing.

“We want to collaborate with South Africa as a strategic partner,” he said. The University West is already actively working with several South African universities, including the UFS, the Central University of Technology, the University of the Western Cape, and Tshwane University of Technology. “This would be the core for us, where we collaborate and find different forms within research and education, not restricted to any faculty or field as such.”

His vision also includes forming a larger ‘Nordic hub’ of connections across Sweden, Norway, and the European Union, along with a ‘regional hub’ in Bloemfontein. This way, universities can share ideas and resources to build a stronger, more connected community for the future.

A need for work-integrated learning

A working example of this partnership between University West and the UFS is the collaborative focus on integrated learning between Prof Liezel Massyn, Associate Professor in the UFS Business School, and Prof Kristina Areskoug Josefsson, Professor in Work-integrated Learning and Health Science from University West. They have a mutual commitment to improve educational practices through international partnerships and to advance integrated learning strategies. Together, they have already co-authored a research article and presented their findings at five conferences this year.

Prof Massyn said she realised that there is a need for work-integrated learning, specifically in the UFS Business School. “Initially, I thought our students were working, so they didn't need the work-integrated learning component. I then realised it could actually add a lot more value.”

Prof Nicolene Barkhuizen, Director of the UFS Business School, highlighted how this venture aligns with the university’s Vision 130, which aims to expand the UFS’ global footprint. “This partnership is an optimisation of the collaboration to contribute to Vision 130, expanding our reach globally while bringing practical value locally. We are looking forward to a very fruitful collaboration,” she said.

Speaking on behalf of the Faculty of Economic and Management Sciences, acting Dean Prof Frans Prinsloo discussed the potential for future projects. “Now that we have this collaboration agreement, there are many opportunities we can explore further,” he stated.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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