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07 November 2024 | Story André Damons | Photo Supplied
Implementation Science Workshop 2024
Building capacity for the use of implementation science. The Principal Investigators of the project; Dr Phindile Shangase from UFS, left, and Dr Lebogang Mogongoa from the Central University of Technology, with Dr Shalini Ahuja from King’s College London, centre, who facilitated the workshops.

The Division of Public Health at the University of the Free State (UFS) together with the Central University of Technology (CUT), held a successful workshop (first phase) for their project: Capacity building for the use of implementation science in various typologies in low- and middle-income countries for the prevention and/or management of the quadruple burden of disease.

According to the National Institute for Health as well as the World Health Organisation, implementation science supports innovative approaches to identifying, understanding, and overcoming barriers to the adoption, adaptation, integration, scale-up and sustainability of evidence-based interventions, tools, policies, and guidelines. Implementation research therefore pertains to gathering and analysing implementation evidence of effectiveness that determines if the intervention works in real-world circumstances.

The Principal Investigator at UFS is Dr Phindile Shangase from the Division of Public Health, supported by colleagues in the Division, as well as the CUT team, led by Dr Lebogang Mogongoa. The first phase of the project took place from 14-17 October 2024 with the first two days held at UFS.

In this co-funded project, UFS and CUT engage in partnership capacity building for academics and postgraduate students. At the UFS, the project is funded by the Office of the Deputy Vice-Chancellor: Research and Internationalisation and resulted from the CUT and UFS Joint Research Programme Research Grant 9th Call.

Contributing to evidence-based policies and practices

Dr Shangase says the workshops of this project were well attended by academics, researchers, postgraduate and postdoctoral students from different disciplines, and community organisations, including programme managers, as well as clinicians from the Department of Health. Other stakeholders and international students who could not travel for face-to-face interactions attended live on UFS YouTube.

Workshops were facilitated by Dr Shalini Ahuja from King’s College, London, who is an international expert and experienced in this field through engaging in research as well as field facilitation in various low- and middle-income countries.

Says Dr Shangase: “Implementation science is the study of methods and strategies to promote the systematic uptake of research findings. It contributes to evidence-based policies and practices and ensures that they are implemented effectively to achieve their intended outcomes, through the identification of barriers and facilitators to implementation. These strategies can therefore be integrated effectively into routine practice in healthcare, public health, and other fields.

“Reviewed studies indicate that the effectiveness of implementation research is noted in the identification and investigation of factors that address disparities in healthcare delivery and outcomes, including those within the health systems and in the population. In simple terms, the goal of implementation science is to understand how and why some interventions succeed while others fail, and to identify the best ways to integrate research-backed interventions into real-world settings for maximum impact and to ensure they continue to be used and remain effective over time,” says Dr Shangase.

Purpose of project

According to her, in the context of South Africa, implementation science has potential to assist in addressing the quadruple burden of disease which comprise of these colliding epidemics: maternal, newborn and child health; HIV/AIDS and tuberculosis (TB); non-communicable diseases (e.g. cardiovascular diseases, chronic respiratory diseases, cancers, and diabetes); and violence and injury.

The purpose of this project, explains Dr Shangase, is to capacitate academics and postgraduate students at the UFS and CUT as well as community stakeholders with knowledge and skills regarding the processes and factors involved in the successful integration of evidence-based public health improvement interventions into routine practice and policy.

“Implementation science offers a strategic, data-driven approach for South Africa, especially in addressing the country’s unique and complex healthcare challenges. These advantages stem from its focus on translating evidence-based interventions into real-world practice, addressing the quadruple burden of disease and helping overcome systemic obstacles to effective healthcare delivery.

“These advantages make implementation science a vital tool for improving health outcomes and achieving sustainable public health progress in South Africa.”

The next phase of this project is expected to be more innovative and takes place between February and March in 2025 with the inclusion of a multistakeholder team.

News Archive

Extending new discoveries in the deep subsurface – UFS paper published in Nature Communications
2015-11-30



Scanning electron microscopy of some of the Eukarya recovered from two different mines. (a) Dochmiotrema sp. (Plathyelminthes), (b) A. hemprichi (Annelida), (c) Mylonchulus brachyurus (Nematoda), (d) Amphiascoides (Arthropoda). Scale bar, 50 µm (a,b), 100 µm (c), 20 µm (d).

Following the discovery of the first Eukarya in the deep subsurface (Nature, 2010) by a research group from the Department of Microbial, Biochemical, and Food Biotechnology at the University of the Free State (UFS) and their international collaborators, intense interest has developed in understanding the diversity of more complex organisms living in these extreme environments.

Prof Gaetan Borgonie from Extreme Life Isyensya, together with a group of UFS researchers, took this research further, resulting in a paper on this research released in Nature Communications – impact factor 11.47.  This paper is an extension of the first reports of more complex life at great depths, and their abilities to survive these harsh conditions.

Ten authors from the UFS contributed with the array of expertise needed to define this discovery. The group was supported by staff from the different mining groups, long-term leading collaborators from the USA and Canada, and the idea specialist driver of the paper, Prof Borganie.

“After a sampling campaign that lasted more than two years, we identified that Platyhelminthes, Rotifera, Annelida and Arthropoda are thriving at 1.4 km depths in fissure water up to 12,000-years old in the South African mines of Driefontein and Kopanang,” said Prof Borgonie, who was appointed as associated researcher in the Department of Microbial, Biochemical, and Food Biotechnology.

This paper really opens a “can of worms” so to speak. According to Prof Esta van Heerden from the Department of Microbial, Biochemical and Food Biotechnology at the UFS they extended to define protozoa and fungi. “However, they are present in low numbers,” she said.

Characterisation of the different species reveals that many are opportunistic organisms. In house-adapted video equipment was used to film inside the fissure for the home of the organisms.

This is the first-known study to demonstrate the in situ distribution of biofilms on fissure rock faces using video documentation. Calculations suggest that food, not dissolved oxygen, is the limiting factor for population growth. The discovery of a group of complex multicellular organisms in the underground has important implications for the search for life on other planets in our solar system.

More articles

The strange beasts that live in solid rock deep underground
A microscopic ‘zoo’ is found deep, deep underground

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