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29 October 2024 | Story André Damons | Photo Supplied
NRF Researchers 2024
First NRF rating: From top left: Dr Andronicus Akinyelu, Lecturer in the Department of Computer Science and Informatics, received his first Y2 rating, Dr Monique de Milander, Senior Lecturer in the Department of Exercise and Sport Sciences, obtained a C3 rating, while Dr Calvin D. Ullrich, Senior Lecturer in Interdisciplinary Theology: Historical and Constructive Theology, obtained a Y1 rating. Bottom left: Prof Maria Tsakeni, Associate Professor in the School of Mathematics, Natural Sciences, and Technology Education, Prof Matildie Wium, Associate Professor in the Odeion School of Music, and Dr Weldemichael Tesfuhuney, a senior lecturer in the Department of Soil, Crop, and Climate Sciences, all obtained a C2 rating.

The list of National Research Foundation (NRF)-rated researchers at the University of the Free State (UFS) is growing, with 22 researchers recently receiving their first NRF rating, and 14 others obtaining new ratings after re-evaluation. This list is expected to grow even more with results slowly filtering in.

Profs Jan van der Watt, Research Fellow in the Department of Old and New Testament Studies, and Felicity Burt from the Division of Virology and SARChI Research Chair in vector-borne and zoonotic pathogens, are the latest NRF B1 rated researchers. While this is Prof Van der Watt’s first NRF rating, Prof Burt has increased her NRF rating from B3 to B1. The UFS now has 10 B1 rated researchers.

In addition to the new rating of Profs Burt and Van der Watt, the UFS also boasts seven new C1 rated researchers, 14 new C2s, five new C3s, seven new Y2s and one Y1 and B3 rated researchers respectively.

Among the researchers who obtained their first NRF ratings are Dr Bimo Abraham Nkhata, Senior Lecturer at the Centre for Environmental Management; Dr Yolandi Schoeman, Senior Lecturer in the Centre for Mineral Biogeochemistry; and Dr Angélique Lewies, Senior Lecturer in the Department of Cardiothoracic Surgery, who has this year been nominated for the prestigious 2023/2024 NSTF-South32 Awards, popularly known as the “Science Oscars” of South Africa. Dr Nkhata obtained a NRF rating in the C2 category, while both Drs Schoeman and Lewies obtained a Y2 rating.

An honour to be among rated researchers

Other researchers who obtained their first NRF rating include Dr Monique de Milander, Senior Lecturer in the Department of Exercise and Sport Sciences, who obtained a C3 rating and Prof Maria Tsakeni, Associate Professor in the School of Mathematics, Natural Sciences, and Technology Education, who received a C2 rating.

Dr De Milander, a Kinderkineticist who works with the motor development of young children, says she was very surprised to obtain a C3 rating. “I feel honoured receiving this NRF rating. To know that other researchers are reading my work and finding it relevant. It takes a lot of dedication and patience, since this is an endurance race and not a sprint. You need to work many hours, read a lot of new articles and write the articles themselves.

“In addition, collecting the data is not always possible without the assistance of our students at the Department of Exercise and Sport Sciences as fieldworkers. I would like to acknowledge them because without them my research projects would not always be feasible. Furthermore, the publication process is also timeous, thus a lot of time elapses before you start to see the results of your work,” explains Dr De Milander.

According to her, the current project for her NRF rating is the assessment of motor development, attentional deficit hyperactive disorder, anthropometry and academic performance in low- and high-socio-economic primary school learners in Mangaung.

Prof Tsakeni, whose research focuses on the design and implementation of innovative instructional strategies and curriculum innovations in science classrooms, says she is honoured to be among the rated researchers. “The recognition motivates me to continue pushing myself to climb the ladder of rated researchers. The rating makes me feel affirmed to continue with my research work. I am grateful to the Faculty of Education, the UFS, and the NRF for giving me the opportunity and support.”

She would like to upscale the impact of her research by engaging in large-scale studies, international comparative studies, international collaborations, and one day, be a visiting scholar at some prestigious universities.

“The innovations in science classrooms include integrating inquiry-based practical work, education for sustainable development (ESD) and STEM education. The instructional strategies include inquiry-based learning and integrating educational technologies in the classrooms,” says Prof Tsakeni.

Recognition for long-term academic work

Newly C2 rated researcher, Dr Weldemichael Tesfuhuney, a senior lecturer in the Department of Soil, Crop, and Climate Sciences, says: “As an agrometeorologist by profession, I feel a profound mix of pride and motivation after receiving NRF-rating recognition for my long-term academic work.

“This acknowledgment validates my years of dedication in understanding the intricate relationship between meteorology and agriculture. It boosts my confidence and reaffirms my commitment to advancing my academic and research goals.

“Such recognition is a pivotal moment for me; it serves as a powerful reminder of the impact of my research on agricultural practices, particularly in addressing the challenges posed by climate change in arid and semi-arid regions.”

Dr Tesfuhuney, whose research deepens understanding of how meteorological patterns affect agricultural practices, making a significant contribution to the field of Agrometeorology, has established a robust research portfolio focused on the challenges of meteorology and agriculture in arid and semi-arid regions. He has spearheaded several long-term research initiatives, including In-field Rainwater Harvesting (IRWH) techniques, intercropping practices, micrometeorology, and crop modelling simulations, all aimed at improving crop productivity for smallholder farming communities in rural areas.

Currently, Dr Tesfuhuney is expanding his research on underutilised crops in the region, focusing on how these crops can help smallholder farmers adapt to the impacts of climate change while improving nutritional security.

Work on the right track

Dr Calvin D. Ullrich, Senior Lecturer in Interdisciplinary Theology: Historical and Constructive Theology, who obtained a Y1 rating, says though there is much talk in South African academia about the necessity of an NRF rating which is not always positive (at least in the broader humanities), the NRF does have its strengths.

“I think it pushes one to critically consider one’s work as a whole; to reflect on its current shape and to identify lacuna within a broader trajectory. There is something generative about this process in and of itself. Feelings of relief but also of affirmation then: a rigorous peer-review system which acts as a metric, according to which one might be able to say, ‘my work is somehow on the right track’ — I think there is certainly value in that.”

According to Dr Ullrich, pursuing your research and making critical interventions into your field, means the rating can follow as a necessary consequence. Research for him, he continues, like most academics, is deeply personal and exhilarating, and so acquiring the rating can also be seen as just another internal aspect of the research process as opposed to being contingent to it.

He has several research projects currently in the research pipeline including smaller writing projects relating to eco-phenomenology and eco-theology and political theology in South Africa. A larger project, scheduled to begin later next year and continuing for the next three years (2025-2028), involves a more intense investigation of the social dimensions of ‘affects’ and how this could be deployed within the specific social context of faith communities.

It’s humbling

For Prof Matildie Wium, Associate Professor in the Odeion School of Music, her first C2 rating is not only an honour for her contribution to her field, but also a humbling moment, because the experience of applying for a rating makes clear how much room remains for growth.

Her research has two main focus areas: (a) 20th-century South African art music, studied from an analytical-hermeneutic perspective, and (b) the musical practices and experiences of mid-19th-century female opera singers in London, studied by means of archival documents.

“I am currently working on converting conference papers I had delivered recently into articles, mainly on the South African art music side of my endeavours. There are papers about Mimi Coertse (in collaboration with my colleague Dr Albertus Engelbrecht), Hubert du Plessis’s Opus 24 (in collaboration with my past student Dr Melissa Gerber), and Michael Mosoeu Moerane’s tone poem Fatshe la Heso under development.

“I am also co-writing a paper analysing some items from ethnomusicologist Gerhard Kubik’s archive of Àló (Yoruba storytelling) with my colleague Dr Joseph Kunnuji,” says Prof Wium.

Dedication, resilience, and strategic focus

Dr Andronicus Akinyelu, Lecturer in the Department of Computer Science and Informatics, called his first Y2 rating incredibly rewarding as it reaffirms his hard work and perseverance have not been in vain. “It also serves as a great source of motivation for me to continue pushing boundaries and striving for excellence in my academic and research pursuits. I am deeply grateful to God for this achievement. I am delighted to have been successful. It is an important milestone in my academic journey,” he says.

According to him, achieving an NRF rating requires a combination of dedication, resilience, and strategic focus. It involves publishing high-quality research in top-tier journals, supervising postgraduate students, and contributing significantly as a first or corresponding author on various projects.

“My research spans multiple cutting-edge areas, including machine learning, deep learning, computer vision, medical diagnosis, sustainable agriculture, and responsible artificial intelligence (AI). Currently, I’m collaborating with international researchers to develop deep-learning techniques that predict treatment responses in cancer patients.

“This research has the potential to significantly advance personalised medicine by enabling more accurate and timely interventions. Additionally, I am deeply committed to promoting responsible AI by developing frameworks and models that prioritise ethics in AI systems,” says Dr Akinyelu.

Prof Vasu Reddy, Deputy Vice-Chancellor of Research and Internationalisation says: “Congratulations to all our newly rated researchers. We are expecting more in the coming months as the results of applications slowly filter in. We are extremely proud of our rated researchers for the recognition they have received. This is in large part the result of their contribution to producing high-quality research. There are many benefits that accrue to our researchers who are rated, namely an investment in their scholarship, including UFS support, as well as opportunities to further enhance their academic trajectory.”

Other researchers who obtained their first NRF rating: 

  • Dr Ernie Langner (Department of Chemistry, C2)
  • Prof Danrè Strydom (Odeion School of Music, C3) 
  • Prof Lizemari Hugo (School of Nursing, Y2)
  • Prof V.R Clark (Director: Afromontane Research Unit, C1) 
  • Dr Clement Masakure (Department of History, C2)
  • Prof Mariette Reyneke (Department of Public Law, C2)
  • Dr Soumya Ghosh (Department of Genetics, C3)
  • Prof Patricks V Otomo (Department of Zoology and Entomology, C2)
  • Dr Tafadzwa Maramura (Department of Public Administration and Management, Y2)
  • Dr Yibeltal Terefe (Department of Mathematics and Applied Mathematics, C3)
  • Dr Bianca Naude (Department of Political Studies and Governance, Y2)
  • Dr Andronicus Akinyelu (Department of Computer Science and Informatics, Y2)
  • Dr Sogo Abolarin (Office of the Dean: Natural Sciences, Y2)

Researchers who obtained a new rating after re-evaluation: 

  • Prof Carlien Pohl-Albertyn (Microbiology and Biochemistry, went from a C2 to C1 rating)
  • Dr Kate Law (International Studies Group, C1 previously Y1)
  • Prof Paul Fouche (Department Psychology, C1 previously C3)
  • Prof Michelle Engelbrecht (Centre for Health Systems Research & Development, went from C3 to C2)
  • Dr Joseph Sempa (Department of Biostatistics, C3 previously Y2)
  • Prof Oliver Nyambi (Department of English, went from Y1 to C1)
  • Dr Marianne Conradie-Bekker (Department of Chemistry, went from Y2 to C2)
  • Dr Marieka Gryzenhout (Department of Genetics, C1 previously C2)
  • Prof Martin Nyaga (Next Generation Sequencing (NGS) Unit, previously held a Y2 now a B3)
  • Prof Botma Visser (Plant Sciences, went from C2 to C1)
  • Prof Kobus Schoeman (Practical and Missional Theology, went from C3 to C2)
  • Prof Louise Van Den Berg (Nutrition and Dietetics, C3 to C2)
  • Prof Christoph Gauert (Geology, went from C3 to C2) 

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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