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29 October 2024 | Story Leonie Bolleurs | Photo Supplied
Thandi Mazibuko
Thandi Mazibuko, with her presentation: LED there be light, was the overall institutional winner in the PhD category and the runner-up in the national competition of this year’s 3MT competition.

The Centre for Graduate Support (CGS) recently (11 October 2024) hosted the annual institutional Three-Minute Thesis Competition (3MT), which was followed by the national competition (25 October). This year, the nationals took place on the UFS Bloemfontein Campus. According to Tshepiso Mokoena, responsible for Research Capacity Development in CGS, the participating master’s and PhD students gave well-prepared presentations. The competition aims to equip postgraduate students with valuable communication and presentation skills.

She says that postgraduate students are encouraged to do research that will benefit the community. “To do this, students should be able to communicate and present their research to a non-specialist audience. The 3MT competition trains and equips them with skills that they will use in their community and workplace,” she noted.

Overall PhD winner

The overall winner in the PhD category of the UFS competition was Thandi Mazibuko with her presentation: LED there be light. Thandi was also announced as the first runner-up at the national competition.

Growing up in Qwaqwa, Thandi’s passion for mathematics and the natural sciences led her to pursue a BSc Physics degree at the UFS in 2013, followed by an honours at the UFS. She then completed her MSc at the University of the Western Cape and worked as a science engagement intern at iThemba LABS in Cape Town, which inspired her to start a YouTube channel with more than 4 800 subscribers, called Thandisayensi. On this channel she uploads Physical Sciences videos for learners in grades 10-12.

Thandi states that she loves learning and being in learning environments; in 2022, she registered for a PhD in Solid State Physics under the supervision of Prof Hendrik Swart and Prof David Motaung.

Her research focuses on synthesising a phosphor material capable of emitting red, green, and blue light, which, when combined, creates the perception of white light. Thandi compared the research process to cooking, explaining how the preparation of phosphors resembles food preparation. She believes that relatable language, analogies, and storytelling are important tools in science communication.

Thandi says that this competition was a valuable platform to improve her science communication skills. “It is an interesting challenge to explain your work in 180 seconds to an audience with different backgrounds,” she said, adding that she is excited to represent the UFS at the national competition.

The other winners

Each department hosts its own 3MT competition, and the winners and runners-up in both the master’s and PhD categories then represent their faculty in the institutional competition.

The master’s category winners from other faculties were:

  • Faculty of Economic and Management Sciences: Evodia Mohoanyane with Does SI/tutoring work and what about it works? Evodia was also the overall winner in the institutional competition in the master’s category.
  • The Humanities: Yonwaba Matshobotiyana with Of Speaking and Visibility: Black Women Poets' Voices in South Africa
  • Health Sciences: Viwe Fokazi with Establishing a novel 3D doxorubicin-resistant triple-negative breast cancer spheroid model

In the PhD category, the winners were:

  • Economic and Management Sciences: Chrizaan Grobbelaar with The use of gamification to enhance retirement preparedness of millennials
  • The Humanities: Sheree Pretorius with The Psychometric Properties of the Prison Adjustment Questionnaire (PAQ) among South African Male Incarcerated Offenders

With Thandi, first runner-up of the institutional competition, Chrizaan, participated in the national 3MT competition. Universities such as the Nelson Mandela University, UNISA, University of KwaZulu-Natal, University of the Western Cape, University of Johannesburg, and the Central University of Technology were also present. 

News Archive

#Women'sMonth: Save the children
2017-08-10

Description: Trudi O'Neill Tags: : rotaviruses, young children, Dr Trudi O’Neill, Department of Microbial, Biochemical and Food Biotechnology, vaccine 

Dr Trudi O’Neill, Senior lecturer in the Department of
Microbial, Biochemical and Food Biotechnology.
Photo: Anja Aucamp

Dr Trudi O’Neill, Senior lecturer in the Department of Microbial, Biochemical and Food Biotechnology, is conducting research on rotavirus vaccines.

Dr O’Neill was inspired to conduct research on this issue through her fascination with the virus. “The biology of rotaviruses, especially the genome structure and the virus’ interaction with the host, is fascinating.”

“In fact, it is estimated that, globally, ALL children will be infected with rotavirus before the age of five, irrespective of their socio-economic standing. However, infants and young children in poor countries are more vulnerable due to inadequate healthcare. The WHO estimates that approximately 215 000 deaths occur each year. This roughly equates to eight Airbus A380 planes, the largest commercial carrier with a capacity of approximately 500 seats, filled with only children under the age of five, crashing each week of every year.”

Alternative to expensive medicines 
“Currently, there are two vaccines that have been licensed for global use. However, these vaccines are expensive and poor countries, where the need is the greatest, are struggling to introduce them sustainably. It is therefore appealing to study rotaviruses, as it is scientifically challenging, but could at the same time have an impact on child health,” Dr O’Neill said.

The main focus of Dr O’Neill’s research is to develop a more affordable vaccine that can promote child vaccination in countries/areas that cannot afford the current vaccines.

All about a different approach 

When asked about the most profound finding of her research, Dr O’Neill responded: “It is not so much a finding, but rather the approach. My rotavirus research group is making use of yeast as vehicle to produce a sub-unit vaccine. These microbes are attractive, as they are relatively easy to manipulate and cheap to cultivate. Downstream production costs can therefore be reduced. The system we use was developed by my colleagues, Profs Koos Albertyn and Martie Smit, and allows for the potential use of any yeast. This enables us to screen a vast number of yeasts in order to identify the best yeast producer.”

Vaccination recently acquired a bad name in the media for its adverse side effects. As researcher, Dr O’Neill has this to say: “Vaccines save lives. By vaccinating your child, you don’t just protect your own child from a potentially deadly infection, but also other children in your community that might be too young to be vaccinated or have pre-existing health problems that prevents vaccination.” 

A future without rotavirus vaccination?

Dr O’Neill believes a future without rotavirus vaccination will be a major step backwards, as the impact of rotavirus vaccines has been profound. “Studies in Mexico and Malawi actually show a reduction in deaths. A colleague in Mozambique has commented on the empty hospital beds that amazed both clinicians and scientists only one year after the introduction of the vaccine in that country. Although many parents, mostly in developed countries, don’t have to fear dehydrating diarrhoea and potential hospitalisation of their babies due to rotavirus infection anymore, such an infection could still be a death sentence in countries that have not been able to introduce the vaccine in their national vaccination programmes,” she said. 

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