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29 October 2024 | Story Leonie Bolleurs | Photo Supplied
Thandi Mazibuko
Thandi Mazibuko, with her presentation: LED there be light, was the overall institutional winner in the PhD category and the runner-up in the national competition of this year’s 3MT competition.

The Centre for Graduate Support (CGS) recently (11 October 2024) hosted the annual institutional Three-Minute Thesis Competition (3MT), which was followed by the national competition (25 October). This year, the nationals took place on the UFS Bloemfontein Campus. According to Tshepiso Mokoena, responsible for Research Capacity Development in CGS, the participating master’s and PhD students gave well-prepared presentations. The competition aims to equip postgraduate students with valuable communication and presentation skills.

She says that postgraduate students are encouraged to do research that will benefit the community. “To do this, students should be able to communicate and present their research to a non-specialist audience. The 3MT competition trains and equips them with skills that they will use in their community and workplace,” she noted.

Overall PhD winner

The overall winner in the PhD category of the UFS competition was Thandi Mazibuko with her presentation: LED there be light. Thandi was also announced as the first runner-up at the national competition.

Growing up in Qwaqwa, Thandi’s passion for mathematics and the natural sciences led her to pursue a BSc Physics degree at the UFS in 2013, followed by an honours at the UFS. She then completed her MSc at the University of the Western Cape and worked as a science engagement intern at iThemba LABS in Cape Town, which inspired her to start a YouTube channel with more than 4 800 subscribers, called Thandisayensi. On this channel she uploads Physical Sciences videos for learners in grades 10-12.

Thandi states that she loves learning and being in learning environments; in 2022, she registered for a PhD in Solid State Physics under the supervision of Prof Hendrik Swart and Prof David Motaung.

Her research focuses on synthesising a phosphor material capable of emitting red, green, and blue light, which, when combined, creates the perception of white light. Thandi compared the research process to cooking, explaining how the preparation of phosphors resembles food preparation. She believes that relatable language, analogies, and storytelling are important tools in science communication.

Thandi says that this competition was a valuable platform to improve her science communication skills. “It is an interesting challenge to explain your work in 180 seconds to an audience with different backgrounds,” she said, adding that she is excited to represent the UFS at the national competition.

The other winners

Each department hosts its own 3MT competition, and the winners and runners-up in both the master’s and PhD categories then represent their faculty in the institutional competition.

The master’s category winners from other faculties were:

  • Faculty of Economic and Management Sciences: Evodia Mohoanyane with Does SI/tutoring work and what about it works? Evodia was also the overall winner in the institutional competition in the master’s category.
  • The Humanities: Yonwaba Matshobotiyana with Of Speaking and Visibility: Black Women Poets' Voices in South Africa
  • Health Sciences: Viwe Fokazi with Establishing a novel 3D doxorubicin-resistant triple-negative breast cancer spheroid model

In the PhD category, the winners were:

  • Economic and Management Sciences: Chrizaan Grobbelaar with The use of gamification to enhance retirement preparedness of millennials
  • The Humanities: Sheree Pretorius with The Psychometric Properties of the Prison Adjustment Questionnaire (PAQ) among South African Male Incarcerated Offenders

With Thandi, first runner-up of the institutional competition, Chrizaan, participated in the national 3MT competition. Universities such as the Nelson Mandela University, UNISA, University of KwaZulu-Natal, University of the Western Cape, University of Johannesburg, and the Central University of Technology were also present. 

News Archive

Nanotechnology breakthrough at UFS
2010-08-19

 Ph.D students, Chantel Swart and Ntsoaki Leeuw


Scientists at the University of the Free State (UFS) made an important breakthrough in the use of nanotechnology in medical and biological research. The UFS team’s research has been accepted for publication by the internationally accredited Canadian Journal of Microbiology.

The UFS study dissected yeast cells exposed to over-used cooking oil by peeling microscopically thin layers off the yeast cells through the use of nanotechnology.

The yeast cells were enlarged thousands of times to study what was going on inside the cells, whilst at the same time establishing the chemical elements the cells are composed of. This was done by making microscopically small surgical incisions into the cell walls.

This groundbreaking research opens up a host of new uses for nanotechnology, as it was the first study ever in which biological cells were surgically manipulated and at the same time elemental analysis performed through nanotechnology. According to Prof. Lodewyk Kock, head of the Division Lipid Biotechnology at the UFS, the study has far reaching implications for biological and medical research.

The research was the result of collaboration between the Department of Microbial, Biochemical and Food Biotechnology, the Department of Physics (under the leadership of Prof. Hendrik Swart) and the Centre for Microscopy (under the leadership of Prof.Pieter van Wyk).

Two Ph.D. students, Chantel Swart and Ntsoaki Leeuw, overseen by professors Kock and Van Wyk, managed to successfully prepare yeast that was exposed to over-used cooking oil (used for deep frying of food) for this first ever method of nanotechnological research.

According to Prof. Kock, a single yeast cell is approximately 5 micrometres long. “A micrometre is one millionth of a metre – in laymen’s terms, even less than the diameter of a single hair – and completely invisible to the human eye.”

Through the use of nanotechnology, the chemical composition of the surface of the yeast cells could be established by making a surgical incision into the surface. The cells could be peeled off in layers of approximately three (3) nanometres at a time to establish the effect of the oil on the yeast cell’s composition. A nanometre is one thousandth of a micrometre.

Each cell was enlarged by between 40 000 and 50 000 times. This was done by using the Department of Physics’ PHI700 Scanning Auger Nanoprobe linked to a Scanning Electron Microscope and Argon-etching. Under the guidance of Prof. Swart, Mss. Swart en Leeuw could dissect the surfaces of yeast cells exposed to over-used cooking oil. 

The study noted wart like outgrowths - some only a few nanometres in diameter – on the cell surfaces. Research concluded that these outgrowths were caused by the oil. The exposure to the oil also drastically hampered the growth of the yeast cells. (See figure 1)  

Researchers worldwide have warned about the over-usage of cooking oil for deep frying of food, as it can be linked to the cause of diseases like cancer. The over-usage of cooking oil in the preparation of food is therefore strictly regulated by laws worldwide.

The UFS-research doesn’t only show that over-used cooking oil is harmful to micro-organisms like yeast, but also suggests how nanotechnology can be used in biological and medical research on, amongst others, cancer cells.

 

Figure 1. Yeast cells exposed to over-used cooking oil. Wart like protuberances/ outgrowths (WP) is clearly visible on the surfaces of the elongated yeast cells. With the use of nanotechnology, it is possible to peel off the warts – some with a diameter of only a few nanometres – in layers only a few nanometres thick. At the same time, the 3D-structure of the warts as well as its chemical composition can be established.  

Media Release
Issued by: Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za  
18 August 2010
 

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